• 2628 Citations
  • 28 h-Index
19942019
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Research Output 1994 2019

  • 2628 Citations
  • 28 h-Index
  • 83 Article
  • 2 Review article
  • 1 Chapter
1994
144 Citations (Scopus)

One pot synthesis of haloacetylenes from trimethylsilylacetylenes

Nishikawa, T., Shibuya, S., Hosokawa, S. & Isobe, M., 1994 Jul 1, In : Synlett. 1994, 7, p. 485-486 2 p.

Research output: Contribution to journalArticle

Functional groups
Substrates
esperamicin A1
7 Citations (Scopus)

Synthetic Studies on Grayanotoxins. Stereocontrolled Construction of CD-Ring of Grayanotoxins

Kan, T., Oikawa, M., Hosokawa, S., Yanagiya, M., Matsuda, F. & Shirahama, H., 1994 Oct 1, In : Synlett. 1994, 10, p. 805-808 4 p.

Research output: Contribution to journalArticle

Poisons
8 Citations (Scopus)

Synthetic Studies on Grayanotoxins Diastereofacially Selective Diels-Alder Reaction of 4-Benzyloxy-2-pentenoate

Kan, T., Oikawa, M., Hosokawa, S., Yanagiya, M., Matsuda, F. & Shirahama, H., 1994 Oct 1, In : Synlett. 1994, 10, p. 801-804 4 p.

Research output: Contribution to journalArticle

Poisons
Mirrors
1,3-butadiene
85 Citations (Scopus)

Total synthesis of (-)-grayanotoxin III

Kan, T., Hosokawa, S., Nara, S., Oikawa, M., Ito, S., Matsuda, F. & Shirahama, H., 1994, In : Journal of Organic Chemistry. 59, 19, p. 5532-5534 3 p.

Research output: Contribution to journalArticle

Diterpenes
Cyclization
grayanotoxin III
1995
64 Citations (Scopus)

Synthesis of two Diastereoisomers of A/B Fragment of Ciguatoxin

Hosokawa, S. & Isobe, M., 1995 Nov 1, In : Synlett. 1995, 11, p. 1179-1180 2 p.

Research output: Contribution to journalArticle

Ciguatoxins
Pentoses
Acetylene
Hexoses
Cyclization
1996
57 Citations (Scopus)

Partial Synthesis of Ciguatoxin, an A/B/C Fragment

Hosokawa, S. & Isobe, M., 1996, In : Synlett. 1996, 4, p. 351-352 2 p.

Research output: Contribution to journalArticle

Ciguatoxins
Acetylene
Cyclization
Cations
Derivatives
64 Citations (Scopus)

syn-trans fused bicyclic ether formation via acetylene-biscobalthexacarbonyl complex

Isobe, M., Hosokawa, S. & Kira, K., 1996, In : Chemistry Letters. 6, p. 473-474 2 p.

Research output: Contribution to journalArticle

Ciguatoxins
Marine Toxins
Acetylene
Ethers
Cyclization
1997

C-Glycosidation of silylpropargyl alcohols into glucals

Saeeng, R., Hosokawa, S. & Isobe, M., 1997 Jan 1, In : Nippon Nogeikagaku Kaishi. 71, p. 110-119 10 p.

Research output: Contribution to journalArticle

Calcium Gluconate
Alcohols
2 Citations (Scopus)

Enzyme inhibitors, synthesis and approach to mechanism

Isobe, M., Tsuboi, K., Hosokawa, S., Bamba, M., Kira, K., Shibuya, S., Ohtani, I. I., Nishikawa, T. & Ichikawa, Y., 1997 Mar, In : Pure and Applied Chemistry. 69, 3, p. 401-406 6 p.

Research output: Contribution to journalArticle

Ciguatoxins
Phosphoprotein Phosphatases
Tetrodotoxin
Enzyme Inhibitors
Enzymes
107 Citations (Scopus)

Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin A

Nicolau, K. C., Xu, J. Y., Kim, S., Ohshima, T., Hosokawa, S. & Pfefferkorn, J., 1997, In : Journal of the American Chemical Society. 119, 46, p. 11353-11354 2 p.

Research output: Contribution to journalArticle

sarcodictyin A
eleutherobin
113 Citations (Scopus)

Total synthesis of eleutherobin

Nicolaou, K. C., Van Delft, F., Ohshima, T., Vourloumis, D., Xu, J., Hosokawa, S., Pfefferkorn, J., Kim, S. & Li, T., 1997, In : Angewandte Chemie - International Edition in English. 36, 22, p. 2520-2524 5 p.

Research output: Contribution to journalArticle

Biological Products
Antineoplastic Agents
eleutherobin
1998
67 Citations (Scopus)

1,4-anti induction in C-glycosylation of pentose glycals

Hosokawa, S., Kirschbaum, B. & Isobe, M., 1998 Apr 2, In : Tetrahedron Letters. 39, 14, p. 1917-1920 4 p.

Research output: Contribution to journalArticle

Glycosylation
Pentoses
Stereoselectivity
Regioselectivity
Ions
88 Citations (Scopus)

Reductive decomplexation of biscobalthexacarbonyl acetylenes into olefins

Hosokawa, S. & Isobe, M., 1998 Apr 23, In : Tetrahedron Letters. 39, 17, p. 2609-2612 4 p.

Research output: Contribution to journalArticle

Acetylene
Alkynes
Alkenes
Derivatives
tributyltin
123 Citations (Scopus)

Stereocontrolled synthesis and reactivity of sugar acetylenes

Isobe, M., Nishizawa, R., Hosokawa, S. & Nishikawa, T., 1998 Dec 21, In : Chemical Communications. 24, p. 2665-2676 12 p.

Research output: Contribution to journalArticle

Alkynes
Acetylene
Sugars
Cobalt
Derivatives
64 Citations (Scopus)

Synthesis and biological activity of sarcodictyins

Nicolaou, K. C., Kim, S., Pfefferkorn, J., Xu, J., Ohshima, T., Hosokawa, S., Vourloumis, D. & Li, T., 1998 Jun 5, In : Angewandte Chemie - International Edition. 37, 10, p. 1418-1421 4 p.

Research output: Contribution to journalArticle

Bioactivity
Antineoplastic Agents
101 Citations (Scopus)

Total synthesis of eleutherobin and eleuthosides A and B

Nicolaou, K. C., Ohshima, T., Hosokawa, S., Van Delft, F. L., Vourloumis, D., Xu, J. Y., Pfefferkorn, J. & Kim, S., 1998 Sep 2, In : Journal of the American Chemical Society. 120, 34, p. 8674-8680 7 p.

Research output: Contribution to journalArticle

Glycosides
Esterification
Hydrogenation
Screening
Molecules
99 Citations (Scopus)

Total synthesis of sarcodictyins A and B

Nicolaou, K. C., Xu, J. Y., Kim, S., Pfefferkorn, J., Ohshima, T., Vourloumis, D. & Hosokawa, S., 1998 Sep 2, In : Journal of the American Chemical Society. 120, 34, p. 8661-8673 13 p.

Research output: Contribution to journalArticle

Esterification
Aldehydes
Anhydrides
Tubulin
Biological Products
1999
87 Citations (Scopus)

Mirror image synthesis left ends of ciguatoxin and gambiertoxin 4b

Hosokawa, S. & Isobe, M., 1999 Jan 8, In : Journal of Organic Chemistry. 64, 1, p. 37-48 12 p.

Research output: Contribution to journalArticle

Ciguatoxins
Mirrors
Pentoses
Acetylene
Stereochemistry
54 Citations (Scopus)

Total synthesis and chemical biology of the sarcodictyins

Nicolaou, K. C., Pfefferkorn, J., Xu, J., Winssinger, N., Ohshima, T., Kim, S., Hosokawa, S., Vourloumis, D., Van Delft, F. & Li, T., 1999 Sep, In : Chemical and Pharmaceutical Bulletin. 47, 9, p. 1199-1213 15 p.

Research output: Contribution to journalArticle

Diterpenes
Structure-Activity Relationship
Tubulin
Cytotoxicity
Paclitaxel

Total synthesis of sarcodictyins A and B: Solid- and solution-phase synthesis and biological evaluation of combinatorial sarcodictyin libraries

Nicolaou, K. C., Winssinger, N., Vourloumis, D., Ohshima, T., Kim, S., Pfefferkorn, J., Xu, J. Y., Li, T. & Hosokawa, S., 1999 Dec, In : Chemtracts. 12, 14, p. 1006-1012 7 p.

Research output: Contribution to journalArticle

Solid-Phase Synthesis Techniques
Libraries
2000
58 Citations (Scopus)

Novel stereoselective construction of a quaternary carbon: Application to synthesis of the cyclopentenedione moiety of madindolines

Hosokawa, S., Sekiguchi, K., Enemoto, M. & Kobayashi, S., 2000 Aug 12, In : Tetrahedron Letters. 41, 33, p. 6429-6433 5 p.

Research output: Contribution to journalArticle

Alkylation
Condensation
Carbon
29 Citations (Scopus)

Total synthesis of madindoline A

Hosokawa, S., Sekiguchi, K., Hayase, K., Hirukawa, Y. & Kobayashi, S., 2000 Aug 12, In : Tetrahedron Letters. 41, 33, p. 6435-6439 5 p.

Research output: Contribution to journalArticle

Skeleton
Aldehydes
Acids
Condensation
Derivatives
2001
24 Citations (Scopus)

Stereochemical control of tertiary alcohol: Aldol condensation of lactate derivatives

Kamino, T., Murata, Y., Kawai, N., Hosokawa, S. & Kobayashi, S., 2001 Jul 30, In : Tetrahedron Letters. 42, 31, p. 5249-5252 4 p.

Research output: Contribution to journalArticle

Condensation
Lactic Acid
Alcohols
Derivatives
Stereochemistry
16 Citations (Scopus)

Total synthesis of madindoline A

Hosokawa, S. & Kobayashi, S., 2001 Nov, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 59, 11, p. 1103-1108 6 p.

Research output: Contribution to journalArticle

Bearings (structural)
Amination
Alkylation
Aldehydes
Amines
2002
29 Citations (Scopus)

Stereocontrolled preparation of 1,2-diol with quaternary chiral center

Murata, Y., Kamino, T., Hosokawa, S. & Kobayashi, S., 2002 Nov 4, In : Tetrahedron Letters. 43, 45, p. 8121-8123 3 p.

Research output: Contribution to journalArticle

Lactates
Bearings (structural)
Stereochemistry
Titanium
Anions
2003
15 Citations (Scopus)

1,3-Rearrangement of ketene-N,O-acetals

Suzuki, T., Inui, M., Hosokawa, S. & Kobayashi, S., 2003 Apr 28, In : Tetrahedron Letters. 44, 18, p. 3713-3716 4 p.

Research output: Contribution to journalArticle

Lewis Acids
Acetals
Stereochemistry
Alkylation
Carbon
32 Citations (Scopus)

Stereoselective construction of a quaternary carbon substituted with multifunctional groups: Application to the concise synthesis of (+)-ethosuximide

Abe, T., Suzuki, T., Sekiguchi, K., Hosokawa, S. & Kobayashi, S., 2003 Dec 22, In : Tetrahedron Letters. 44, 52, p. 9303-9305 3 p.

Research output: Contribution to journalArticle

Ethosuximide
Imides
Stereoselectivity
Carbonyl compounds
Iodides
2004
11 Citations (Scopus)

Acetoxyl group directed cyclization promoted by SmI2: Directing group determined stereocomplementarity

Kan, T., Hosokawa, S., Nara, S., Tamiya, H., Shirahama, H. & Matsuda, F., 2004 Dec 10, In : Journal of Organic Chemistry. 69, 25, p. 8956-8958 3 p.

Research output: Contribution to journalArticle

Cyclization
Ketones
Alkenes
Aldehydes
Acetates
23 Citations (Scopus)

Highly efficient total synthesis of (+)-citreoviral

Murata, Y., Kamino, T., Aoki, T., Hosokawa, S. & Kobayashi, S., 2004 Jun 14, In : Angewandte Chemie - International Edition. 43, 24, p. 3175-3177 3 p.

Research output: Contribution to journalArticle

Imides
Alcohols
citreoviral
3-hydroxybutanal
139 Citations (Scopus)

Remote asymmetric induction with vinylketene silyl N,O-acetal

Shirokawa, S. I., Kamiyama, M., Nakamura, T., Okada, M., Nakazaki, A., Hosokawa, S. & Kobayashi, S., 2004 Oct 27, In : Journal of the American Chemical Society. 126, 42, p. 13604-13605 2 p.

Research output: Contribution to journalArticle

Stereoselectivity
Acetals
Polyketides
3-hydroxybutanal
titanium tetrachloride
2005
10 Citations (Scopus)

Stereoselective 1,5-rearrangement of vinylketene-N,O-acetals: Novel vinylogous Ferrier reaction

Inui, M., Hosokawa, S., Nakazaki, A. & Kobayashi, S., 2005 May 2, In : Tetrahedron Letters. 46, 18, p. 3245-3248 4 p.

Research output: Contribution to journalArticle

Lewis Acids
Acetals
Methylene Chloride
Ions
Experiments
49 Citations (Scopus)

The first total synthesis of trichostatin D

Hosokawa, S., Ogura, T., Togashi, H. & Tatsuta, K., 2005 Jan 10, In : Tetrahedron Letters. 46, 2, p. 333-337 5 p.

Research output: Contribution to journalArticle

Glycosylation
Acetals
trichostatin D
65 Citations (Scopus)

Total synthesis of selected bioactive natural products: Illustration of strategy and design

Tatsuta, K. & Hosokawa, S., 2005 Dec, In : Chemical Reviews. 105, 12, p. 4707-4729 23 p.

Research output: Contribution to journalArticle

Biological Products
Glycosylation
Nitrogen
2006
98 Citations (Scopus)

Enantioselective total synthesis of convolutamydines B and E

Nakamura, T., Shirokawa, S. I., Hosokawa, S., Nakazaki, A. & Kobayashi, S., 2006 Feb 16, In : Organic Letters. 8, 4, p. 677-679 3 p.

Research output: Contribution to journalArticle

Isatin
synthesis
aldehydes
Aldehydes
configurations
33 Citations (Scopus)

The first total synthesis and structural determination of actinopyrone A

Hosokawa, S., Yokota, K., Imamura, K., Suzuki, Y., Kawarasaki, M. & Tatsuta, K., 2006 Jul 24, In : Tetrahedron Letters. 47, 30, p. 5415-5418 4 p.

Research output: Contribution to journalArticle

Pyrones
Methylation
actinopyrone A
25 Citations (Scopus)

The first total synthesis and structural determination of lagunamycin

Hosokawa, S., Kuroda, S., Imamura, K. & Tatsuta, K., 2006 Aug 28, In : Tetrahedron Letters. 47, 35, p. 6183-6186 4 p.

Research output: Contribution to journalArticle

Condensation
Nuclear magnetic resonance
Oxidation
lagunamycin
25 Citations (Scopus)

Total syntheses of bioactive natural products from carbohydrates

Tatsuta, K. & Hosokawa, S., 2006 Jul, In : Science and Technology of Advanced Materials. 7, 5, p. 397-410 14 p.

Research output: Contribution to journalArticle

Carbohydrates
Biological Products
Molecules
Tetracycline
BE 54238B
20 Citations (Scopus)

Total syntheses of polyketide-derived bioactive natural products

Tatsuta, K. & Hosokawa, S., 2006, In : Chemical Record. 6, 4, p. 217-233 17 p.

Research output: Contribution to journalArticle

Polyketides
Biological Products
Polycyclic Compounds
Lactones
Tetracycline
33 Citations (Scopus)

Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A

Hosokawa, S., Seki, M., Fukuda, H. & Tatsuta, K., 2006 Apr 3, In : Tetrahedron Letters. 47, 14, p. 2439-2442 4 p.

Research output: Contribution to journalArticle

Antitubercular Antibiotics
Cycloaddition Reaction
Lactones
Anti-Bacterial Agents
ribonolactone
2007
18 Citations (Scopus)

The first total synthesis and structural determination of (+)-BE-52440A

Tatsuta, K., Suzuki, Y., Toriumi, T., Furuya, Y. & Hosokawa, S., 2007 Nov 5, In : Tetrahedron Letters. 48, 45, p. 8018-8021 4 p.

Research output: Contribution to journalArticle

Regioselectivity
Dimerization
Epoxy Compounds
Dimers
BE 52440 A
19 Citations (Scopus)

The first total synthesis and structural determination of TMC-66

Hosokawa, S., Fumiyama, H., Fukuda, H., Fukuda, T., Seki, M. & Tatsuta, K., 2007 Oct 8, In : Tetrahedron Letters. 48, 41, p. 7305-7308 4 p.

Research output: Contribution to journalArticle

Oxidative Coupling
Phenols
Copper
Electrons
TMC 66
16 Citations (Scopus)

The first total synthesis and structural determination of YCM1008A

Tatsuta, K., Yamaguchi, T., Tsuda, Y., Yamaguchi, Y., Hattori, N., Nagai, H. & Hosokawa, S., 2007 Jun 11, In : Tetrahedron Letters. 48, 24, p. 4187-4190 4 p.

Research output: Contribution to journalArticle

Pyridones
YCM 1008A
21 Citations (Scopus)

The first total synthesis of vinaxanthone, a fungus metabolite possessing multiple bioactivities

Tatsuta, K., Kasai, S., Amano, Y., Yamaguchi, T., Seki, M. & Hosokawa, S., 2007 Jan 5, In : Chemistry Letters. 36, 1, p. 10-11 2 p.

Research output: Contribution to journalArticle

Cycloaddition
Metabolites
Bioactivity
Fungi
Molecules
48 Citations (Scopus)

Total synthesis of khafrefungin using highly stereoselective vinylogous Mukaiyama aldol reaction

Shirokawa, S. I., Shinoyama, M., Ooi, I., Hosokawa, S., Nakazaki, A. & Kobayashi, S., 2007 Mar 1, In : Organic Letters. 9, 5, p. 849-852 4 p.

Research output: Contribution to journalArticle

acetals
Acetals
synthesis
Ketones
Dehydration
25 Citations (Scopus)

YCM1008A, a novel Ca2+-signaling inhibitor, produced by Fusarium sp. YCM1008

Koizumi, F., Fukumitsu, N., Zhao, J., Chanklan, R., Miyakawa, T., Kawahara, S., Iwamoto, S., Suzuki, M., Kakita, S., Rahayu, E. S., Hosokawa, S., Tatsuta, K. & Ichimura, M., 2007 Jul, In : Journal of Antibiotics. 60, 7, p. 455-458 4 p.

Research output: Contribution to journalArticle

Fusarium
Preclinical Drug Evaluations
Growth
Fermentation
Saccharomyces cerevisiae
2008
52 Citations (Scopus)
Acetals
Biological Products
Functional groups
3-hydroxybutanal
8 Citations (Scopus)

The first total synthesis and structural determination of TMC-264

Tatsuta, K., Furuyama, A., Yano, T., Suzuki, Y., Ogura, T. & Hosokawa, S., 2008 Jun 16, In : Tetrahedron Letters. 49, 25, p. 4036-4039 4 p.

Research output: Contribution to journalArticle

Pyrans
Lewis Acids
Halogenation
Cyclization
Nickel
23 Citations (Scopus)

Total synthesis of an anti-Helicobacter pylori agent, actinopyrone A

Hosokawa, S., Yokota, K., Imamura, K., Suzuki, Y., Kawarasaki, M. & Tatsuta, K., 2008 Sep 1, In : Chemistry - An Asian Journal. 3, 8-9, p. 1415-1421 7 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Organophosphonates
Sulfones
Stereochemistry
Ether
2009
15 Citations (Scopus)
Acetals
Biological Products
Lactic Acid
Carbon
Alcohols
16 Citations (Scopus)

The first total synthesis and structural determination of benzopyrenomycin

Hosokawa, S., Mukaeda, Y., Kawahara, R. & Tatsuta, K., 2009 Dec 2, In : Tetrahedron Letters. 50, 48, p. 6701-6704 4 p.

Research output: Contribution to journalArticle

Cyclization
Skeleton
benzopyrenomycin
benzanthrone
3-hydroxybutanal