• 2587 Citations
  • 28 h-Index
19942019
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Research Output 1994 2019

  • 2587 Citations
  • 28 h-Index
  • 83 Article
  • 2 Review article
  • 1 Chapter
15 Citations (Scopus)

1,3-Rearrangement of ketene-N,O-acetals

Suzuki, T., Inui, M., Hosokawa, S. & Kobayashi, S., 2003 Apr 28, In : Tetrahedron Letters. 44, 18, p. 3713-3716 4 p.

Research output: Contribution to journalArticle

Lewis Acids
Acetals
Stereochemistry
Alkylation
Carbon
67 Citations (Scopus)

1,4-anti induction in C-glycosylation of pentose glycals

Hosokawa, S., Kirschbaum, B. & Isobe, M., 1998 Apr 2, In : Tetrahedron Letters. 39, 14, p. 1917-1920 4 p.

Research output: Contribution to journalArticle

Glycosylation
Pentoses
Stereoselectivity
Regioselectivity
Ions
1 Citation (Scopus)
Imides
Protonation
Lactones
Protons
Betula
11 Citations (Scopus)

Acetoxyl group directed cyclization promoted by SmI2: Directing group determined stereocomplementarity

Kan, T., Hosokawa, S., Nara, S., Tamiya, H., Shirahama, H. & Matsuda, F., 2004 Dec 10, In : Journal of Organic Chemistry. 69, 25, p. 8956-8958 3 p.

Research output: Contribution to journalArticle

Cyclization
Ketones
Alkenes
Aldehydes
Acetates
52 Citations (Scopus)
Acetals
Biological Products
Functional groups
3-hydroxybutanal

Bioinspired Synthesis of the Central Core of Halichonadin H: The Passerini Reaction in a Hypothetical Biosynthesis of Marine Natural Products

Ichikawa, Y., Yamasaki, T., Nakanishi, K., Udagawa, Y., Hosokawa, S. & Masuda, T., 2019 Jan 1, In : Synthesis (Germany). 51, 11, p. 2305-2310 6 p.

Research output: Contribution to journalArticle

Terpenes
Biosynthesis
Biological Products
Cyanides
Formaldehyde

C-Glycosidation of silylpropargyl alcohols into glucals

Saeeng, R., Hosokawa, S. & Isobe, M., 1997 Jan 1, In : Nippon Nogeikagaku Kaishi. 71, p. 110-119 10 p.

Research output: Contribution to journalArticle

Calcium Gluconate
Alcohols
13 Citations (Scopus)

Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages

Oshio, T., Kawashima, R., Kawamura, Y. I., Hagiwara, T., Mizutani, N., Okada, T., Otsubo, T., Inagaki-Ohara, K., Matsukawa, A., Haga, T., Kakuta, S., Iwakura, Y., Hosokawa, S. & Dohi, T., 2014 Apr 8, In : PLoS One. 9, 4, e94445.

Research output: Contribution to journalArticle

CCR Receptors
Macrophages
Peritoneal Macrophages
lipopolysaccharides
Lipopolysaccharides
2 Citations (Scopus)

Concise synthesis of 6-formylindolo[3,2-b]carbazole (FICZ)

Sekine, D., Okeda, S. & Hosokawa, S., 2014, In : Chemistry Letters. 43, 12, p. 1932-1934 3 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Cyclization
Ligands
6-formylindolo(3,2-b)carbazole
3-formylindole
14 Citations (Scopus)

Concise synthesis of reduced propionates by stereoselective reductions combined with the Kobayashi reaction

Nakamura, T., Harachi, M., Kano, T., Mukaeda, Y. & Hosokawa, S., 2013 Jun 21, In : Organic Letters. 15, 12, p. 3170-3173 4 p.

Research output: Contribution to journalArticle

Propionates
Antimalarials
synthesis
Isomers
isomers
15 Citations (Scopus)
Acetals
Biological Products
Lactic Acid
Carbon
Alcohols
98 Citations (Scopus)

Enantioselective total synthesis of convolutamydines B and E

Nakamura, T., Shirokawa, S. I., Hosokawa, S., Nakazaki, A. & Kobayashi, S., 2006 Feb 16, In : Organic Letters. 8, 4, p. 677-679 3 p.

Research output: Contribution to journalArticle

Isatin
synthesis
aldehydes
Aldehydes
configurations
2 Citations (Scopus)

Enzyme inhibitors, synthesis and approach to mechanism

Isobe, M., Tsuboi, K., Hosokawa, S., Bamba, M., Kira, K., Shibuya, S., Ohtani, I. I., Nishikawa, T. & Ichikawa, Y., 1997 Mar, In : Pure and Applied Chemistry. 69, 3, p. 401-406 6 p.

Research output: Contribution to journalArticle

Ciguatoxins
Phosphoprotein Phosphatases
Tetrodotoxin
Enzyme Inhibitors
Enzymes

Epoxide opening transformations in syntheses of acyclic polyketides

Hosokawa, S., 2017 Jan 1, Epoxides: Synthesis, Reactions and Uses. Nova Science Publishers, Inc., p. 1-55 55 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyketides
Epoxy Compounds
Epoxidation
Biological Products
Stereoisomerism
23 Citations (Scopus)

Highly efficient total synthesis of (+)-citreoviral

Murata, Y., Kamino, T., Aoki, T., Hosokawa, S. & Kobayashi, S., 2004 Jun 14, In : Angewandte Chemie - International Edition. 43, 24, p. 3175-3177 3 p.

Research output: Contribution to journalArticle

Imides
Alcohols
citreoviral
3-hydroxybutanal
6 Citations (Scopus)

Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives

Arayama, M., Nehira, T., Maeda, H., Tanaka, K., Miyagawa, H., Ueno, T., Hosokawa, S. & Hashimoto, M., 2015, In : Tetrahedron. 71, 29, p. 4788-4794 7 p.

Research output: Contribution to journalArticle

Helminthosporium
Ascomycota
Chirality
Biosynthetic Pathways
Cytotoxicity
87 Citations (Scopus)

Mirror image synthesis left ends of ciguatoxin and gambiertoxin 4b

Hosokawa, S. & Isobe, M., 1999 Jan 8, In : Journal of Organic Chemistry. 64, 1, p. 37-48 12 p.

Research output: Contribution to journalArticle

Ciguatoxins
Mirrors
Pentoses
Acetylene
Stereochemistry
57 Citations (Scopus)

Novel stereoselective construction of a quaternary carbon: Application to synthesis of the cyclopentenedione moiety of madindolines

Hosokawa, S., Sekiguchi, K., Enemoto, M. & Kobayashi, S., 2000 Aug 12, In : Tetrahedron Letters. 41, 33, p. 6429-6433 5 p.

Research output: Contribution to journalArticle

Alkylation
Condensation
Carbon
143 Citations (Scopus)

One pot synthesis of haloacetylenes from trimethylsilylacetylenes

Nishikawa, T., Shibuya, S., Hosokawa, S. & Isobe, M., 1994 Jul 1, In : Synlett. 1994, 7, p. 485-486 2 p.

Research output: Contribution to journalArticle

Functional groups
Substrates
esperamicin A1
57 Citations (Scopus)

Partial Synthesis of Ciguatoxin, an A/B/C Fragment

Hosokawa, S. & Isobe, M., 1996, In : Synlett. 1996, 4, p. 351-352 2 p.

Research output: Contribution to journalArticle

Ciguatoxins
Acetylene
Cyclization
Cations
Derivatives
12 Citations (Scopus)

Recent development of vinylogous Mukaiyama aldol reactions

Hosokawa, S., 2018 Jan 10, In : Tetrahedron Letters. 59, 2, p. 77-88 12 p.

Research output: Contribution to journalReview article

Polyketides
Biological Products
3-hydroxybutanal
88 Citations (Scopus)

Reductive decomplexation of biscobalthexacarbonyl acetylenes into olefins

Hosokawa, S. & Isobe, M., 1998 Apr 23, In : Tetrahedron Letters. 39, 17, p. 2609-2612 4 p.

Research output: Contribution to journalArticle

Acetylene
Alkynes
Alkenes
Derivatives
tributyltin
7 Citations (Scopus)

Remote Asymmetric Bromination Reaction with Vinylketene Silyl N,O-Acetal and Its Application to Total Synthesis of Pellasoren A

Sekiya, S., Okumura, M., Kubota, K., Nakamura, T., Sekine, D. & Hosokawa, S., 2017 May 5, In : Organic Letters. 19, 9, p. 2394-2397 4 p.

Research output: Contribution to journalArticle

Imides
bromination
acetals
Acetals
Halogenation
4 Citations (Scopus)
Acetals
Biological Products
Carbon
3-hydroxybutanal
ketene
6 Citations (Scopus)
Acetals
Polyketides
Biological Products
Functional groups
Imides
12 Citations (Scopus)

Remote asymmetric induction using acetate-type vinylketene silyl N,O-acetals

Sagawa, N., Sato, H. & Hosokawa, S., 2017 Jan 1, In : Organic Letters. 19, 1, p. 198-201 4 p.

Research output: Contribution to journalArticle

acetals
Acetals
adducts
acetates
induction
137 Citations (Scopus)

Remote asymmetric induction with vinylketene silyl N,O-acetal

Shirokawa, S. I., Kamiyama, M., Nakamura, T., Okada, M., Nakazaki, A., Hosokawa, S. & Kobayashi, S., 2004 Oct 27, In : Journal of the American Chemical Society. 126, 42, p. 13604-13605 2 p.

Research output: Contribution to journalArticle

Stereoselectivity
Acetals
Polyketides
3-hydroxybutanal
titanium tetrachloride
24 Citations (Scopus)

Stereochemical control of tertiary alcohol: Aldol condensation of lactate derivatives

Kamino, T., Murata, Y., Kawai, N., Hosokawa, S. & Kobayashi, S., 2001 Jul 30, In : Tetrahedron Letters. 42, 31, p. 5249-5252 4 p.

Research output: Contribution to journalArticle

Condensation
Lactic Acid
Alcohols
Derivatives
Stereochemistry
29 Citations (Scopus)

Stereocontrolled preparation of 1,2-diol with quaternary chiral center

Murata, Y., Kamino, T., Hosokawa, S. & Kobayashi, S., 2002 Nov 4, In : Tetrahedron Letters. 43, 45, p. 8121-8123 3 p.

Research output: Contribution to journalArticle

Lactates
Bearings (structural)
Stereochemistry
Titanium
Anions
123 Citations (Scopus)

Stereocontrolled synthesis and reactivity of sugar acetylenes

Isobe, M., Nishizawa, R., Hosokawa, S. & Nishikawa, T., 1998 Dec 21, In : Chemical Communications. 24, p. 2665-2676 12 p.

Research output: Contribution to journalArticle

Alkynes
Acetylene
Sugars
Cobalt
Derivatives
10 Citations (Scopus)

Stereoselective 1,5-rearrangement of vinylketene-N,O-acetals: Novel vinylogous Ferrier reaction

Inui, M., Hosokawa, S., Nakazaki, A. & Kobayashi, S., 2005 May 2, In : Tetrahedron Letters. 46, 18, p. 3245-3248 4 p.

Research output: Contribution to journalArticle

Lewis Acids
Acetals
Methylene Chloride
Ions
Experiments
14 Citations (Scopus)

Stereoselective acylation of the E, e -vinylketene silyl N, O -acetal and its application to the synthesis of khafrefungin

Takahashi, Y., Otsuka, M., Harachi, M., Mukaeda, Y. & Hosokawa, S., 2014 Aug 15, In : Organic Letters. 16, 16, p. 4106-4109 4 p.

Research output: Contribution to journalArticle

acylation
acetals
Acylation
Acetals
Anhydrides
10 Citations (Scopus)

Stereoselective Alkylation of the Vinylketene Silyl N,O-Acetal and Its Application to the Synthesis of Mycocerosic Acid

Nakamura, T., Kubota, K., Ieki, T. & Hosokawa, S., 2016 Jan 4, In : Organic Letters. 18, 1, p. 132-135 4 p.

Research output: Contribution to journalArticle

acetals
Acetals
alkylation
Alkylation
Iodides
31 Citations (Scopus)

Stereoselective construction of a quaternary carbon substituted with multifunctional groups: Application to the concise synthesis of (+)-ethosuximide

Abe, T., Suzuki, T., Sekiguchi, K., Hosokawa, S. & Kobayashi, S., 2003 Dec 22, In : Tetrahedron Letters. 44, 52, p. 9303-9305 3 p.

Research output: Contribution to journalArticle

Ethosuximide
Imides
Stereoselectivity
Carbonyl compounds
Iodides
7 Citations (Scopus)

Stereoselective Synthesis of Tabtoxinine-β-lactam by Using the Vinylogous Mukaiyama Aldol Reaction with Acetate-Type Vinylketene Silyl N,O-Acetal and α-Keto-β-lactam

Ejima, H., Wakita, F., Imamura, R., Kato, T. & Hosokawa, S., 2017 May 19, In : Organic Letters. 19, 10, p. 2530-2532 3 p.

Research output: Contribution to journalArticle

glutamine
Lactams
acetals
hydrogenolysis
Acetals
3 Citations (Scopus)

Stereoselective Synthesis of the C27-C48 Moiety of Aflastatin A by a Carbohydrate Strategy Using a Tin(II)-Mediated Aldol Reaction

Murakoshi, S. & Hosokawa, S., 2015 Oct 22, In : Synlett. 26, 17, p. 2437-2441 5 p., st-2015-u0570-l.

Research output: Contribution to journalArticle

Tin
Carbohydrates
Mannosides
Stereochemistry
Aldehydes
22 Citations (Scopus)

Syn-selective kobayashi aldol reaction using acetals

Tsukada, H., Mukaeda, Y. & Hosokawa, S., 2013 Feb 1, In : Organic Letters. 15, 3, p. 678-681 4 p.

Research output: Contribution to journalArticle

acetals
Acetals
Polyketides
Stereoselectivity
Lewis Acids
27 Citations (Scopus)

Syn-selective kobayashi aldol reaction using the E,E-vinylketene silyl N,O -acetal

Mukaeda, Y., Kato, T. & Hosokawa, S., 2012 Oct 19, In : Organic Letters. 14, 20, p. 5298-5301 4 p.

Research output: Contribution to journalArticle

acetals
Acetals
products
Polyketides
musculoskeletal system
9 Citations (Scopus)

Syn selective vinylogous mukaiyama aldol reaction using Z,EVinylketene N,O-acetal with acetals

Sagawa, N., Moriya, H. & Hosokawa, S., 2017 Jan 1, In : Organic Letters. 19, 1, p. 250-253 4 p.

Research output: Contribution to journalArticle

Imides
Polyketides
Stereoselectivity
acetals
Acetals
3 Citations (Scopus)

Synthesis and antileishmanial activity of the core structure of cristaxenicin A

Fumiyama, H., Sadayuki, T., Osada, Y., Goto, Y., Nakao, Y. & Hosokawa, S., 2016 Sep 1, In : Bioorganic and Medicinal Chemistry Letters. 26, 17, p. 4355-4357 3 p.

Research output: Contribution to journalArticle

Aldehydes
Cycloaddition
Cycloaddition Reaction
Ketones
Inhibitory Concentration 50
63 Citations (Scopus)

Synthesis and biological activity of sarcodictyins

Nicolaou, K. C., Kim, S., Pfefferkorn, J., Xu, J., Ohshima, T., Hosokawa, S., Vourloumis, D. & Li, T., 1998 Jun 5, In : Angewandte Chemie - International Edition. 37, 10, p. 1418-1421 4 p.

Research output: Contribution to journalArticle

Bioactivity
Antineoplastic Agents

Synthesis of 24,24-difluoro-1,3-cis-25-dihydroxy-19-norvitamin D3 derivatives and evaluation of their vitamin D receptor-binding affinity

Biswas, T., Akagi, Y., Usuda, K., Yasui, K., Shimizu, I., Okamoto, M., Uesugi, M., Hosokawa, S. & Nagasawa, K., 2016, In : Biological and Pharmaceutical Bulletin. 39, 8, p. 1387-1391 5 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Cholecalciferol
Inhibitory Concentration 50
1,25-dihydroxy-19-norvitamin D3

Synthesis of C3-C21 Segment of Aflastatin A Using Remote Asymmetric Induction Reactions

Murakoshi, S. & Hosokawa, S., 2019 Jan 1, (Accepted/In press) In : Organic Letters.

Research output: Contribution to journalArticle

Acetals
Alkylation
induction
synthesis
aflastatin A

Synthesis of diastereomers of 1,3-cis-25-dihydroxy-19-norvitamin D3

Usuda, K., Biswas, T., Yamaguchi, T., Akagi, Y., Yasui, K., Uesugi, M., Shimizu, I., Hosokawa, S. & Nagasawa, K., 2016, In : Chemical and Pharmaceutical Bulletin. 64, 8, p. 1190-1195 6 p.

Research output: Contribution to journalArticle

Quinic Acid
Benzoates
Nuclear magnetic resonance
Circular Dichroism
Experiments

Synthesis of the C1-C17 Segment of Bafilomycin N

Sato, H. & Hosokawa, S., 2019 Jan 1, In : Synlett. 30, 5, p. 577-580 4 p.

Research output: Contribution to journalArticle

Acetals
3-hydroxybutanal
semipinacol
105 Citations (Scopus)

Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin A

Nicolau, K. C., Xu, J. Y., Kim, S., Ohshima, T., Hosokawa, S. & Pfefferkorn, J., 1997, In : Journal of the American Chemical Society. 119, 46, p. 11353-11354 2 p.

Research output: Contribution to journalArticle

sarcodictyin A
eleutherobin
64 Citations (Scopus)

Synthesis of two Diastereoisomers of A/B Fragment of Ciguatoxin

Hosokawa, S. & Isobe, M., 1995 Nov 1, In : Synlett. 1995, 11, p. 1179-1180 2 p.

Research output: Contribution to journalArticle

Ciguatoxins
Pentoses
Acetylene
Hexoses
Cyclization
9 Citations (Scopus)

Synthetic studies on aculeximycin: Synthesis of C24-C40 segment by kobayashi aldolization and epoxide rearrangements

Kato, T., Sato, T., Kashiwagi, Y. & Hosokawa, S., 2015 May 1, In : Organic Letters. 17, 9, p. 2274-2277 4 p.

Research output: Contribution to journalArticle

epoxy compounds
Epoxy Compounds
Epoxidation
synthesis
epoxidation
7 Citations (Scopus)

Synthetic Studies on Grayanotoxins. Stereocontrolled Construction of CD-Ring of Grayanotoxins

Kan, T., Oikawa, M., Hosokawa, S., Yanagiya, M., Matsuda, F. & Shirahama, H., 1994 Oct 1, In : Synlett. 1994, 10, p. 805-808 4 p.

Research output: Contribution to journalArticle

Poisons
8 Citations (Scopus)

Synthetic Studies on Grayanotoxins Diastereofacially Selective Diels-Alder Reaction of 4-Benzyloxy-2-pentenoate

Kan, T., Oikawa, M., Hosokawa, S., Yanagiya, M., Matsuda, F. & Shirahama, H., 1994 Oct 1, In : Synlett. 1994, 10, p. 801-804 4 p.

Research output: Contribution to journalArticle

Poisons
Mirrors
1,3-butadiene