• 6719 Citations
  • 44 h-Index
1985 …2020

Research output per year

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Research Output

Convenient method for surface modification by patching a freestanding anti-biofouling nanosheet

Fujie, T., Haniuda, H. & Takeoka, S., 2011 Jul 7, In : Journal of Materials Chemistry. 21, 25, p. 9112-9120 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Convenient method to purify hemoglobin

Sakai, H., Takeoka, S., Nishide, H. & Tsuchida, E., 1994 Jan, In : Artificial Cells, Blood Substitutes, and Biotechnology. 22, 3, p. 651-656 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Coordinative nanoporous polymers synthesized with hydrogen-bonded columnar liquid crystals

Ishihara, S., Furuki, Y., Hill, J. P., Ariga, K. & Takeoka, S., 2012 Oct 1, In : Journal of Nanoscience and Nanotechnology. 12, 10, p. 7885-7895 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Critical molecular weight effects in the aggregation of phospholipid vesicles triggered by water-soluble polymers and an integrated glycolipid

Takeoka, S., Sou, K., Arase, S., Ohgushi, T. & Tsuchida, E., 1996 Dec 2, In : Macromolecules. 29, 25, p. 8132-8136 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Decoration of fibrinogen γ-chain peptide on adenosine diphosphate-encapsulated liposomes enhances binding of the liposomes to activated platelets

Tokutomi, K., Tagawa, T., Korenaga, M., Chiba, M., Asai, T., Watanabe, N., Takeoka, S., Handa, M., Ikeda, Y. & Oku, N., 2011 Apr 4, In : International Journal of Pharmaceutics. 407, 1-2, p. 151-157 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Deformability and adhesive force of artificial platelets measured by atomic force microscopy

Wada, T., Okamura, Y., Takeoka, S., Sudo, R., Ikeda, Y. & Tanishita, K., 2009 Dec 1, In : Journal of Biorheology. 23, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Design of nanoparticles for infusing large amounts as artificial blood and their properties

Takeoka, S., 2005 Dec 1, p. 3042-3043. 2 p.

Research output: Contribution to conferencePaper

Destruction and Reconstitution of Polyphospholipid Vesicles with Size Memory

Takeoka, S., Ohgushi, T. & Tsuchida, E., 1995 Nov 1, In : Macromolecules. 28, 23, p. 7660-7666 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Detection of Lipopolysaccharide in Hemoglobin-Vesicles by Limulus Amebocyte Lysate Test with Kinetic-Turbidimetric Gel Clotting Analysis and Pretreatment of Surfactant

Sakai, H., Hisamoto, S., Fukutomi, I., Sou, K., Takeoka, S. & Tsuchida, E., 2004 Feb, In : Journal of Pharmaceutical Sciences. 93, 2, p. 310-321 12 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Developmental trend of artificial blood (artificial red blood cells)

Takeoka, S., 2005 Mar 1, In : Japan Medical Association Journal. 48, 3, p. 135-139 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Development of a ubiquitously transferrable silver-nanoparticle-loaded polymer nanosheet as an antimicrobial coating

Ito, K., Saito, A., Fujie, T., Miyazaki, H., Kinoshita, M., Saitoh, D., Ohtsubo, S. & Takeoka, S., 2016 Apr 1, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 3, p. 585-593 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Development of biodegradable nanosheets as nanoadhesive plaster

Takeoka, S., Okamura, Y., Fujie, T. & Fukui, Y., 2008 Dec 23, In : Pure and Applied Chemistry. 80, 11, p. 2259-2271 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Development of fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute

Okamura, Y., Takeoka, S., Eto, K., Maekawa, I., Fujie, T., Maruyama, H., Ikeda, Y. & Handa, M., 2009 Feb 16, In : Journal of Thrombosis and Haemostasis. 7, 3, p. 470-477 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Development of latanoprost-loaded biodegradable nanosheet as a new drug delivery system for glaucoma

Kashiwagi, K., Ito, K., Haniuda, H., Ohtsubo, S. & Takeoka, S., 2013 Aug 28, In : Investigative Ophthalmology and Visual Science. 54, 8, p. 5629-5637 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Disk-like assemblies of a synthetic glycolipid and their association with concanavalin A

Takeoka, S., Sou, K., Ohgushi, T. & Tsuchida, E., 1998 Jan 1, In : Supramolecular Science. 5, 1-2, p. 159-162 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation

Goda, N., Suzuki, K., Naito, M., Takeoka, S., Tsuchida, E., Ishimura, Y., Tamatani, T. & Suematsu, M., 1998 Feb 1, In : Journal of Clinical Investigation. 101, 3, p. 604-612 9 p.

Research output: Contribution to journalArticle

Open Access
241 Citations (Scopus)

Drift and fluctuating motion of artificial platelet during adhesion process near the wall

Tobimatsu, H., Paragon, A., Okamura, Y., Takeoka, S., Sudo, R. & Tanishita, K., 2010 Oct 22, 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech. p. 1075-1078 4 p. (IFMBE Proceedings; vol. 31 IFMBE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Drift and fluctuating motion of artificial platelets during the lateral transport and adhesion process near the wall

Tobimatsu, H., Paragon, A., Okamura, Y., Takeoka, S., Sudo, R., Ikeda, Y. & Tanishita, K., 2013 Jan 1, In : Journal of Biorheology. 26, 1-2, p. 11-20 10 p.

Research output: Contribution to journalArticle

Dual therapeutic action of antibiotic-loaded nanosheets for the treatment of gastrointestinal tissue defects

Fujie, T., Saito, A., Kinoshita, M., Miyazaki, H., Ohtsubo, S., Saitoh, D. & Takeoka, S., 2010 Aug 1, In : Biomaterials. 31, 24, p. 6269-6278 10 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Effective control of massive venous bleeding by "multioverlapping therapy" using polysaccharide nanosheets in a rabbit inferior vena cava injury model

Hagisawa, K., Saito, A., Kinoshita, M., Fujie, T., Otani, N., Shono, S., Park, Y. K. & Takeoka, S., 2013 Jul 1, In : Journal of Vascular Surgery: Venous and Lymphatic Disorders. 1, 3, p. 289-297 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effective Encapsulation of Proteins into Size-Controlled Phospholipid Vesicles Using Freeze-Thawing and Extrusion

Sou, K., Naito, Y., Endo, T., Takeoka, S. & Tsuchida, E., 2003 Sep 1, In : Biotechnology Progress. 19, 5, p. 1547-1552 6 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Effect of Hb-encapsulation with vesicles on H2O2 reaction and lipid peroxidation

Takeoka, S., Teramura, Y., Atoji, T. & Tsuchida, E., 2002 Nov 1, In : Bioconjugate Chemistry. 13, 6, p. 1302-1308 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Effect of Phase Transition on Photosensitized Radical Polymerization of Diene-Containing Lipids as Liposomes1

Ohno, H., Takeoka, S., Iwai, H. & Tsuchida, E., 1989 Jan 1, In : Macromolecules. 22, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
3 Citations (Scopus)

Effect of the nanoformulation of siRrNAa-lipid assemblies on their cellular uptake and immune stimulation

Kubota, K., Onishi, K., Sawaki, K., Li, T., Mitsuoka, K., Sato, T. & Takeoka, S., 2017 Jul 19, In : International Journal of Nanomedicine. 12, p. 5121-5133 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Effects of hemoglobin vesicles, a liposomal artificial oxygen carrier, on hematological responses, complement and anaphylactic reactions in rats

Abe, H., Azuma, H., Yamaguchi, M., Fujihara, M., Ikeda, H., Sakai, H., Takeoka, S. & Tsuchida, E., 2007 Mar 1, In : Artificial Cells, Blood Substitutes, and Biotechnology. 35, 2, p. 157-172 16 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro

Wakamoto, S., Fujihara, M., Abe, H., Yamaguchi, M., Azuma, H., Ikeda, H., Takeoka, S. & Tsuchida, E., 2005 Jun 15, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33, 2, p. 101-111 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Effects of poly(Ethyleneglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and rantes release in vitro

Wakamoto, S., Fujihara, M., Abe, H., Sakai, H., Takeoka, S., Tsuchida, E., Ikeda, H. & Ikebuchi, K., 2001 May 22, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 29, 3, p. 191-201 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on N-formyl-methionyl-leucyl-phenylalanine-induced responses of polymorphonuclear neutrophils in vitro

Ito, T., Fujihara, M., Abe, H., Yamaguchi, M., Wakamoto, S., Takeoka, S., Sakai, H., Tsuchida, E., Ikeda, H. & Ikebuchi, K., 2001 Dec 1, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 29, 6, p. 427-437 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effects of the pH-controlled hemoglobin vesicles by CO2 gas

Park, S., Kose, T., Hamasaki, M., Takeoka, S., Nishide, H. & Tsuchida, E., 1998 Jan 1, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 26, 5-6, p. 497-506 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Efficient differentiation and polarization of primary cultured neurons on poly(lactic acid) scaffolds with microgrooved structures

Otomo, A., Ueda, M. T., Fujie, T., Hasebe, A., Suematsu, Y., Okamura, Y., Takeoka, S., Hadano, S. & Nakagawa, S., 2020 Dec 1, In : Scientific reports. 10, 1, 6716.

Research output: Contribution to journalArticle

Open Access

Elastic kirigami patch for electromyographic analysis of the palm muscle during baseball pitching

Yamagishi, K., Nakanishi, T., Mihara, S., Azuma, M., Takeoka, S., Kanosue, K., Nagami, T. & Fujie, T., 2019 Dec 1, In : NPG Asia Materials. 11, 1, 80.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Elastomer-based MEMS optical interferometric transducers for highly sensitive surface stress sensing for biomolecular detection

Takahashi, K., Fujie, T., Teramoto, R., Takahashi, I., Sato, N., Takeoka, S. & Sawada, K., 2019 Jan 1, In : MRS Communications.

Research output: Contribution to journalArticle

Electropolymerization of pyrrole on a tantalum electrode

Yamamoto, K., Park, Y. S., Takeoka, S. & Tsuchida, E., 1991 Nov 25, In : Journal of Electroanalytical Chemistry. 318, 1-2, p. 171-181 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier

Sakai, H., Sato, A., Masuda, K., Takeoka, S. & Tsuchida, E., 2008 Jan 18, In : Journal of Biological Chemistry. 283, 3, p. 1508-1517 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Encapsulation of Hb into unsaturated lipid vesicles and γ‐ray polymerization

Sakai, H., Takeoka, S., Yokohama, H., Nishide, H. & Tsuchida, E., 1992, In : Polymers for Advanced Technologies. 3, 7, p. 389-394 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Enhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport

Li, T. & Takeoka, S., 2014 Jun 5, In : International Journal of Nanomedicine. 9, 1, p. 2849-2861 13 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Enhancement of hemostatic ability of dodecapeptide-conjugated phospholipid vesicles by encapsulation of a platelet aggregation-induced factor

Okamura, Y., Maekawa, I., Handa, M., Ikeda, Y. & Takeoka, S., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

Enzymatic elimination of hydrogen peroxide by a methemoglobin/L-tyrosine system

Atoji, T., Yatami, H., Aihara, M. & Takeoka, S., 2007 Nov 1, In : Artificial Cells, Blood Substitutes, and Biotechnology. 35, 6, p. 555-567 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Erratum: Virus inactivation in hemoglobin solution by heat treatment (Artificial Cells, Blood Subsitutes, and Immobilization Biotechnology (29:5) (381-388))

Abe, H., Ikebuchi, K., Hirayama, J., Fujihara, M., Takeoka, S., Sakai, H., Tsuchida, E. & Ikeda, H., 2002 Jan 1, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 30, 1, 1 p.

Research output: Contribution to journalComment/debate

Establishment of a total liquid ventilation system using saline-based oxygen micro/nano-bubble dispersions in rats

Kakiuchi, K., Matsuda, K., Harii, N., Sou, K., Aoki, J. & Takeoka, S., 2015 Sep 4, In : Journal of Artificial Organs. 18, 3, p. 220-227 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Evaluation of cationic assemblies constructed with amino acid based lipids for plasmid DNA delivery

Obata, Y., Suzuki, D. & Takeoka, S., 2008 May 1, In : Bioconjugate Chemistry. 19, 5, p. 1055-1063 9 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Evaluation of cationic liposomes composed of an amino acid-based lipid for neuronal transfection

Obata, Y., Ciofani, G., Raffa, V., Cuschieri, A., Menciassi, A., Dario, P. & Takeoka, S., 2010 Feb, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Evaluation of H2O2 elimination activity by methemoglobin / L-tyrosine and application to hemoglobin vesicles

Aihara, M., Atoji, T. & Takeoka, S., 2006 Dec 1. 1 p.

Research output: Contribution to conferencePaper

99 Citations (Scopus)

Evaluation of the capabilities of a hemoglobin vesicle as an artificial oxygen carrier in a rat exchange transfusion model

Izumi, Y., Sakai, H., Kose, T., Hamada, K., Takeoka, S., Yoshizu, A., Horinouchi, H., Kato, R., Nishide, H., Tsuchida, E. & Kobayashi, K., 1997 Aug 1, In : ASAIO Journal. 43, 4, p. 289-297 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Evaluation of the influence of ionization states and spacers in the thermotropic phase behaviour of amino acid-based cationic lipids and the transfection efficiency of their assemblies

Sarker, S. R., Arai, S., Murate, M., Takahashi, H., Takata, M., Kobayashi, T. & Takeoka, S., 2012 Jan 17, In : International Journal of Pharmaceutics. 422, 1-2, p. 364-373 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Evasion of the accelerated blood clearance phenomenon by polysarcosine coating of liposomes

Son, K., Ueda, M., Taguchi, K., Maruyama, T., Takeoka, S. & Ito, Y., 2020 Jun 10, In : Journal of Controlled Release. 322, p. 209-216 8 p.

Research output: Contribution to journalArticle

Extracellular pH imaging of a plant leaf with a polyelectrolyte multilayered nanosheet

Someya, D., Arai, S., Fujie, T. & Takeoka, S., 2018, In : RSC Advances. 8, 62, p. 35651-35657 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fabrication, Properties, and Biomedical Applications of Nanosheets

Fujie, T., Okamura, Y. & Takeoka, S., 2011 Jun 7, Functional Polymer Films. Wiley-VCH, Vol. 2. p. 907-931 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Citations (Scopus)