• 6597 Citations
  • 43 h-Index
1985 …2020

Research output per year

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Research Output

2011

Fabrication, Properties, and Biomedical Applications of Nanosheets

Fujie, T., Okamura, Y. & Takeoka, S., 2011 Jun 7, Functional Polymer Films. Wiley-VCH, Vol. 2. p. 907-931 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Citations (Scopus)

Fluorescent "Turn-on" system utilizing a quencher-conjugated peptide for specific protein labeling of living cells

Arai, S., Yoon, S. I., Murata, A., Takabayashi, M., Wu, X., Lu, Y., Takeoka, S. & Ozaki, M., 2011 Jan 7, In : Biochemical and Biophysical Research Communications. 404, 1, p. 211-216 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Free-standing poly(l-lactic acid) nanofilms loaded with superparamagnetic nanoparticles

Taccola, S., Desii, A., Pensabene, V., Fujie, T., Saito, A., Takeoka, S., Dario, P., Menciassi, A. & Mattoli, V., 2011 May 3, In : Langmuir. 27, 9, p. 5589-5595 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Gas bioengineering using hemoglobin-vesicles for versatile clinical applications

Sakai, H., Takeoka, S. & Kobayashi, K., 2011 Jul 1, In : Current Pharmaceutical Design. 17, 22, p. 2352-2359 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Increased viscosity of hemoglobin-based oxygen carriers retards NO-binding when perfused through narrow gas-permeable tubes

Sakai, H., Okuda, N., Takeoka, S. & Tsuchida, E., 2011 Mar 1, In : Microvascular Research. 81, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Intravenous infusion of Hb-vesicles (artificial oxygen carriers) after repetitive blood exchange with a series of plasma expanders (water-soluble biopolymers) in a rat model

Sakai, H., Miyagawa, N., Horinouchi, H., Takeoka, S., Takaori, M., Tsuchida, E. & Kobayashi, K., 2011 Aug, In : Polymers for Advanced Technologies. 22, 8, p. 1216-1222 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)

Nabetani, T., Makino, A., Hullin-Matsuda, F., Hirakawa, T. A., Takeoka, S., Okino, N., Ito, M., Kobayashi, T. & Hirabayashi, Y., 2011 Jun, In : Journal of Lipid Research. 52, 6, p. 1294-1302 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Novel technique of overlaying a poly-L-lactic acid nanosheet for adhesion prophylaxis and fixation of intraperitoneal onlay polypropylene mesh in a rabbit model

Fujino, K., Kinoshita, M., Saitoh, A., Yano, H., Nishikawa, K., Fujie, T., Iwaya, K., Kakihara, M., Takeoka, S., Saitoh, D. & Tanaka, Y., 2011 Oct, In : Surgical Endoscopy. 25, 10, p. 3428-3436 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Ultrastructural analysis of thrombin-induced interaction between human platelets and liposomes carrying fibrinogen γ-chain dodecapeptide as a synthetic platelet substitute

Suzuki, H., Okamura, Y., Ikeda, Y., Takeoka, S. & Handa, M., 2011 Dec 1, In : Thrombosis Research. 128, 6, p. 552-559 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Ultra-thin conductive free-standing PEDOT/PSS nanofilms

Greco, F., Zucca, A., Taccola, S., Menciassi, A., Fujie, T., Haniuda, H., Takeoka, S., Dario, P. & Mattoli, V., 2011 Nov 21, In : Soft Matter. 7, 22, p. 10642-10650 9 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)
2010

Adhesion and proliferation of skeletal muscle cells on single layer poly(lactic acid) ultra-thin films

Ricotti, L., Taccola, S., Pensabene, V., Mattoli, V., Fujie, T., Takeoka, S., Menciassi, A. & Dario, P., 2010 Oct 1, In : Biomedical Microdevices. 12, 5, p. 809-819 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

A nano-fibrous assembly of collagen-hyaluronic acid for controlling cell-adhesive properties

Fujie, T., Furutate, S., Niwa, D. & Takeoka, S., 2010 Oct 7, In : Soft Matter. 6, 19, p. 4672-4676 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Construction of a 'turn-on' fluorescent probe system for His-tagged proteins

Murata, A., Arai, S., Yoon, S. I., Takabayashi, M., Ozaki, M. & Takeoka, S., 2010 Dec 1, In : Bioorganic and Medicinal Chemistry Letters. 20, 23, p. 6905-6908 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Drift and fluctuating motion of artificial platelet during adhesion process near the wall

Tobimatsu, H., Paragon, A., Okamura, Y., Takeoka, S., Sudo, R. & Tanishita, K., 2010 Oct 22, 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech. p. 1075-1078 4 p. (IFMBE Proceedings; vol. 31 IFMBE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dual therapeutic action of antibiotic-loaded nanosheets for the treatment of gastrointestinal tissue defects

Fujie, T., Saito, A., Kinoshita, M., Miyazaki, H., Ohtsubo, S., Saitoh, D. & Takeoka, S., 2010 Aug 1, In : Biomaterials. 31, 24, p. 6269-6278 10 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Evaluation of cationic liposomes composed of an amino acid-based lipid for neuronal transfection

Obata, Y., Ciofani, G., Raffa, V., Cuschieri, A., Menciassi, A., Dario, P. & Takeoka, S., 2010 Feb, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
95 Citations (Scopus)

Hemoglobin encapsulation in vesicles retards NO and CO binding and O 2 release when perfused through narrow gas-permeable tubes

Sakai, H., Okuda, N., Sato, A., Yamaue, T., Takeoka, S. & Tsuchida, E., 2010 Mar 1, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 3, p. H956-H965

Research output: Contribution to journalArticle

18 Citations (Scopus)

Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane properties and their hemostatic effects as a platelet substitute

Okamura, Y., Katsuno, S., Suzuki, H., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2010 Dec 20, In : Journal of Controlled Release. 148, 3, p. 373-379 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Sealing effect of a polysaccharide nanosheet for murine cecal puncture

Fujie, T., Kinoshita, M., Shono, S., Saito, A., Okamura, Y., Saitoh, D. & Takeoka, S., 2010 Jul 1, In : Surgery. 148, 1, p. 48-58 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Synthesis and self-assembling behavior of a porphyrin bearing multiple meso-conjugated barbiturates

Arai, S., Okamura, T. & Takeoka, S., 2010 Sep 29, In : Tetrahedron Letters. 51, 39, p. 5177-5180 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Visualization of liposomes carrying fibrinogen γ-chain dodecapeptide accumulated to sites of vascular injury using computed tomography

Okamura, Y., Eto, K., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2010 Apr 1, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 2, p. 391-396 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2009

Adhesive, flexible, and robust polysaccharide nanosheets integrated for tissue-defect repair

Fujie, T., Matsutani, N., Kinoshita, M., Okamura, Y., Saito, A. & Takeoka, S., 2009 Sep 24, In : Advanced Functional Materials. 19, 16, p. 2560-2568 9 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Biocompatibility study of hemoglobin vesicles, cellular-type artificial oxygen carriers, with human umbilical cord hematopoietic stem/progenitor cells using an in vitro expansion system

Yamaguchi, M., Fujihara, M., Wakamoto, S., Sakai, H., Takeoka, S., Tsuchida, E., Hamada, H., Azuma, H. & Ikeda, H., 2009 May 1, In : ASAIO Journal. 55, 3, p. 200-205 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Boron nitride nanotubes: A novel vector for targeted magnetic drug delivery

Ciofani, G., Raffa, V., Yu, J., Chen, Y., Obata, Y., Takeoka, S., Menciassi, A. & Cuschieri, A., 2009 Jun 1, In : Current Nanoscience. 5, 1, p. 33-38 6 p.

Research output: Contribution to journalReview article

70 Citations (Scopus)

Deformability and adhesive force of artificial platelets measured by atomic force microscopy

Wada, T., Okamura, Y., Takeoka, S., Sudo, R., Ikeda, Y. & Tanishita, K., 2009 Dec 1, In : Journal of Biorheology. 23, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Development of fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute

Okamura, Y., Takeoka, S., Eto, K., Maekawa, I., Fujie, T., Maruyama, H., Ikeda, Y. & Handa, M., 2009 Feb 16, In : Journal of Thrombosis and Haemostasis. 7, 3, p. 470-477 8 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Fabrication and characterization of ultra-thin magnetic films for biomedical applications

Mattoli, V., Pensabene, V., Fujie, T., Taccola, S., Menciassi, A., Takeoka, S. & Dario, P., 2009 Sep 1, In : Procedia Chemistry. 1, 1, p. 28-31 4 p.

Research output: Contribution to journalConference article

Open Access
14 Citations (Scopus)

Fabrication of free-standing albumin-nanosheets having heterosurfaces

Okamura, Y., Goto, T., Niwa, D., Fukui, Y., Otsuka, M., Motohashi, N., Osaka, T. & Takeoka, S., 2009 Apr 1, In : Journal of Biomedical Materials Research - Part A. 89, 1, p. 233-241 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Fluid resuscitation with artificial oxygen carriers in hemorrhaged rats: Profiles of hemoglobin-vesicle degradation and hematopoiesis for 14 days

Sakai, H., Seishi, Y., Obata, Y., Takeoka, S., Horinouichi, H., Tsuchida, E. & Kobayashi, K., 2009 Feb 1, In : Shock. 31, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Free-standing biodegradable poly(lactic acid) nanosheet for sealing operations in surgery

Okamura, Y., Kabata, K., Kinoshita, M., Saitoh, D. & Takeoka, S., 2009 Nov 20, In : Advanced Materials. 21, 43, p. 4388-4392 5 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Hydrodynamic transformation of a freestanding polymer nanosheet induced by a thermoresponsive surface

Fujie, T., Park, J. Y., Murata, A., Estillore, N. C., Tria, M. C. R., Takeoka, S. & Advincula, R. C., 2009 Jul 29, In : ACS Applied Materials and Interfaces. 1, 7, p. 1404-1413 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Influence of hemoglobin vesicles, cellular-type artificial oxygen carriers, on human umbilical cord blood hematopoietic progenitor cells in vitro

Yamaguchi, M., Fujihara, M., Wakamoto, S., Sakai, H., Takeoka, S., Tsuchida, E., Azuma, H. & Ikeda, H., 2009 Jan 1, In : Journal of Biomedical Materials Research - Part A. 88, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Magnetic nanosheet adhesion to mucosal tissue

Pensabene, V., Mattoli, V., Menciassi, A., Dario, P., Fujie, T. & Takeoka, S., 2009 Dec 1, 2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009. p. 403-407 5 p. 5394686. (2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Mechanism of flocculate formation of highly concentrated phospholipid vesicles suspended in a series of water-soluble biopolymers

Sakai, H., Sato, A., Takeoka, S. & Tsuchida, E., 2009 Aug 10, In : Biomacromolecules. 10, 8, p. 2344-2350 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Motion of polymerized albumin particles in a model arteriole in the presence of red blood cells

Tsuji, T., Takeoka, S., Okamura, Y., Sudo, R., Ikeda, Y. & Tanishita, K., 2009 Dec 1, In : Journal of Biorheology. 23, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel platelet substitutes: Disk-shaped biodegradable nanosheets and their enhanced effects on platelet aggregation

Okamura, Y., Fukui, Y., Kabata, K., Suzuki, H., Handa, M., Ikeda, Y. & Takeoka, S., 2009 Oct 21, In : Bioconjugate Chemistry. 20, 10, p. 1958-1965 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Peculiar flow patterns of RBCs suspended in viscous fluids and perfused through a narrow tube (25 μm)

Sakai, H., Sato, A., Okuda, N., Takeoka, S., Maeda, N. & Tsuchida, E., 2009 Aug 1, In : American Journal of Physiology - Heart and Circulatory Physiology. 297, 2, p. H583-H589

Research output: Contribution to journalArticle

14 Citations (Scopus)
43 Citations (Scopus)

Realization, characterization and functionalization of lipidic wrapped carbon nanotubes

Ciofani, G., Obata, Y., Sato, I., Okamura, Y., Raffa, V., Menciassi, A., Dario, P., Takeda, N. & Takeoka, S., 2009 Feb 1, In : Journal of Nanoparticle Research. 11, 2, p. 477-484 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
21 Citations (Scopus)

Systemic Administration of Hemoglobin Vesicle Elevates Tumor Tissue Oxygen Tension and Modifies Tumor Response to Irradiation

Yamamoto, M., Izumi, Y., Horinouchi, H., Teramura, Y., Sakai, H., Kohno, M., Watanabe, M., Kawamura, M., Adachi, T., Ikeda, E., Takeoka, S., Tsuchida, E. & Kobayashi, K., 2009 Jan 1, In : Journal of Surgical Research. 151, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2008

Development of biodegradable nanosheets as nanoadhesive plaster

Takeoka, S., Okamura, Y., Fujie, T. & Fukui, Y., 2008 Dec 23, In : Pure and Applied Chemistry. 80, 11, p. 2259-2271 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier

Sakai, H., Sato, A., Masuda, K., Takeoka, S. & Tsuchida, E., 2008 Jan 18, In : Journal of Biological Chemistry. 283, 3, p. 1508-1517 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Evaluation of cationic assemblies constructed with amino acid based lipids for plasmid DNA delivery

Obata, Y., Suzuki, D. & Takeoka, S., 2008 May 1, In : Bioconjugate Chemistry. 19, 5, p. 1055-1063 9 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Fabrication of free-standing nanoparticle-fused nanosheets and their hetero-modification using sacrificial film

Okamura, Y., Utsunomiya, S., Suzuki, H., Niwa, D., Osaka, T. & Takeoka, S., 2008 Apr 1, In : Colloids and Surfaces A: Physicochemical and Engineering Aspects. 318, 1-3, p. 184-190 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Haemostatic effects of polymerized albumin particles carrying fibrinogen γ-chain dodecapeptide as platelet substitutes in severely thrombocytopenic rabbits

Okamura, Y., Fujie, T., Nogawa, M., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2008 Jun 1, In : Transfusion Medicine. 18, 3, p. 158-166 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Helical arrangement of a hydrogen-bonded columnar liquid crystal induced by a centered triphenylene derivative bearing chiral side-chains

Ishihara, S., Furuki, Y. & Takeoka, S., 2008 Aug 1, In : Polymers for Advanced Technologies. 19, 8, p. 1097-1104 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Loading of curcumin into macrophages using lipid-based nanoparticles

Sou, K., Inenaga, S., Takeoka, S. & Tsuchida, E., 2008 Mar 20, In : International Journal of Pharmaceutics. 352, 1-2, p. 287-293 7 p.

Research output: Contribution to journalArticle

151 Citations (Scopus)

Magnetic driven alginate nanoparticles for targeted drug delivery

Ciofani, G., Raffa, V., Obata, Y., Menciassi, A., Dario, P. & Takeoka, S., 2008 May 1, In : Current Nanoscience. 4, 2, p. 212-218 7 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)