• 6597 Citations
  • 43 h-Index
1985 …2020

Research output per year

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Research Output

2008

NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers

Sakai, H., Sato, A., Sobolewski, P., Takeoka, S., Frangos, J. A., Kobayashi, K., Intaglietta, M. & Tsuchida, E., 2008 Oct 1, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1784, 10, p. 1441-1447 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2007

A hydrogen-bonded supramolecular hexagonal columnar liquid crystal composed of a tricarboxylic triphenylene and monopyridyl dendrons

Ishihara, S., Furuki, Y. & Takeoka, S., 2007 Feb 5, In : Chemistry Letters. 36, 2, p. 282-283 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Atropisomers of meso-conjugated uracyl porphyrin derivatives and their assembling structures

Arai, S., Niwa, D., Nishide, H. & Takeoka, S., 2007 Jan 4, In : Organic Letters. 9, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of hemoglobin vesicles, a liposomal artificial oxygen carrier, on hematological responses, complement and anaphylactic reactions in rats

Abe, H., Azuma, H., Yamaguchi, M., Fujihara, M., Ikeda, H., Sakai, H., Takeoka, S. & Tsuchida, E., 2007 Mar 1, In : Artificial Cells, Blood Substitutes, and Biotechnology. 35, 2, p. 157-172 16 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Enzymatic elimination of hydrogen peroxide by a methemoglobin/L-tyrosine system

Atoji, T., Yatami, H., Aihara, M. & Takeoka, S., 2007 Nov 1, In : Artificial Cells, Blood Substitutes, and Biotechnology. 35, 6, p. 555-567 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Prolonged hemostatic ability of polyethylene glycol-modified polymerized albumin particles carrying fibrinogen γ-chain dodecapeptide

Okamura, Y., Fujie, T., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2007 Jul 1, In : Transfusion. 47, 7, p. 1254-1262 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Rheological properties of hemoglobin vesicles (artificial oxygen carriers) suspended in a series of plasma-substitute solutions

Sakai, H., Sato, A., Takeoka, S. & Tsuchida, E., 2007 Jul 17, In : Langmuir. 23, 15, p. 8121-8128 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Selective uptake of surface-modified phospholipid vesicles by bone marrow macrophages in vivo

Sou, K., Goins, B., Takeoka, S., Tsuchida, E. & Phillips, W. T., 2007 Jun 1, In : Biomaterials. 28, 16, p. 2655-2666 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Synthesis of porphyrins bearing uracyl groups and their assembly induced by melamine derivatives

Arai, S., Ohshiro, H., Nishide, H. & Takeoka, S., 2007 Jun 1, In : Polymers for Advanced Technologies. 18, 6, p. 497-501 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Ubiquitous transference of a free-standing polysaccharide nanosheet with the development of a nano-adhesive plaster

Fujie, T., Okamura, Y. & Takeoka, S., 2007 Nov 5, In : Advanced Materials. 19, 21, p. 3549-3553 5 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)
2006

Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution: Degradation of HbV and erythropoiesis in a rat spleen for 2 weeks

Sakai, H., Horinouchi, H., Yamamoto, M., Ikeda, E., Takeoka, S., Takaori, M., Tsuchida, E. & Kobayashi, K., 2006 Mar 1, In : Transfusion. 46, 3, p. 339-347 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Analysis of ferrylHb radical reduction by L-tyrosine and its application to hemoglobin vesicles

Atoji, T., Yatami, H., Aihara, M., Tsuchida, E. & Takeoka, S., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

Enhancement of hemostatic ability of dodecapeptide-conjugated phospholipid vesicles by encapsulation of a platelet aggregation-induced factor

Okamura, Y., Maekawa, I., Handa, M., Ikeda, Y. & Takeoka, S., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

Evaluation of H2O2 elimination activity by methemoglobin / L-tyrosine and application to hemoglobin vesicles

Aihara, M., Atoji, T. & Takeoka, S., 2006 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Hemoglobin vesicles as a molecular assembly. Characteristics of preparation process and performances as artificial oxygen carriers

Sakai, H., Sou, K., Takeoka, S., Kobayashi, K. & Tsuchida, E., 2006 Dec 1, Blood Substitutes. Elsevier Ltd, p. 514-522 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Hemoglobin vesicles containing methemoglobin and L-tyrosine to suppress methemoglobin formation in vitro and in vivo

Atoji, T., Aihara, M., Sakai, H., Tsuchida, E. & Takeoka, S., 2006 Sep 1, In : Bioconjugate Chemistry. 17, 5, p. 1241-1245 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Host-guest assembly of pyridinium-conjugated calix[4]arene via cation-π interaction

Ishihara, S. & Takeoka, S., 2006 Jan 9, In : Tetrahedron Letters. 47, 2, p. 181-184 4 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Hydrogen-bonded hexagonal columnar liquid crystal composed of triphenylene and dendrons

Ishihara, S., Furuki, Y. & Takeoka, S., 2006 Dec 1, p. 3825-3826. 2 p.

Research output: Contribution to conferencePaper

Interaction of hemoglobin vesicles, a cellular-type artificial oxygen carrier, with human plasma: Effects on coagulation, kallikrein-kinin, and complement systems

Abe, H., Fujihara, M., Azuma, H., Ikeda, H., Ikebuchi, K., Takeoka, S., Tsuchida, E. & Harashima, H., 2006 Apr 1, In : Artificial Cells, Blood Substitutes, and Biotechnology. 34, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
28 Citations (Scopus)

O2-binding properties of albumin hybrid incorporating porphyrinatoiron having histidine derivative

Nakagawa, A., Komatsu, T., Tsuchida, E., Iiduka, M. & Takeoka, S., 2006 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Preparation and evaluation of o/w emulsions with an anionic lipid, containing lipophilic drug

Inenaga, S., Sou, K., Takeoka, S. & Tsuchida, E., 2006 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Kaiyama, K., Sato, I. & Takeoka, S., 2006 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Preparation of pH-sensitive liposomes composed of amino lipids and the release behavior of macromolecules from the liposomes

Obata, Y., Suzuki, D. & Takeoka, S., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

Preparation of protein-adsorbed microsheet using a hydrophilic/hydrophobic patterning substrate

Utsunomiya, S., Okamura, Y. & Takeoka, S., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Satoh, A., Sakai, H., Takeoka, S. & Tsuchida, E., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

The synthesis of meso-conjugated heterocycle porphyrins and their self-assembling structure

Arai, S., Niwa, D., Okamura, T., Nishide, H. & Takeoka, S., 2006 Dec 1, p. 2677-2678. 2 p.

Research output: Contribution to conferencePaper

The synthesis of meso conjugated heterocycle porphyrins and their self-assembly via hydrogen bonds

Arai, S., Niwa, D., Takeoka, S. & Nishide, H., 2006 Oct 19. 1 p.

Research output: Contribution to conferencePaper

2005

Analysis of self-assembly: Porphyrins with uracil and melamine derivatives

Arai, S., Niwa, D., Takeoka, S. & Nishide, H., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Circulatory half-life time of artificial red blood cell (hemoglobin-vesicles) and their distribution to metabolic organs

Sou, K., Goins, B., Phillips, W. T., Sakai, H., Takeoka, S. & Tsuchida, E., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Control of the surface modification of liposomes by poly(ethylene glycol)-lipids with different hydrophilic-hydrophobic balances

Kubota, K., Kanazawa, H., Hisamoto, S. & Takeoka, S., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Design of nanoparticles for infusing large amounts as artificial blood and their properties

Takeoka, S., 2005 Dec 1, p. 3042-3043. 2 p.

Research output: Contribution to conferencePaper

Developmental trend of artificial blood (artificial red blood cells)

Takeoka, S., 2005 Mar 1, In : Japan Medical Association Journal. 48, 3, p. 135-139 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro

Wakamoto, S., Fujihara, M., Abe, H., Yamaguchi, M., Azuma, H., Ikeda, H., Takeoka, S. & Tsuchida, E., 2005 Jun 15, In : Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33, 2, p. 101-111 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Haemostatic effects of fibrinogen y chain dodecapeptide-conjugates as platelet substitutes

Okamura, Y., Maekawa, I., Fujie, T., Takeoka, S., Handa, M. & Ikeda, Y., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Haemostatic effects of polymerized albumin particles carrying fibrinogen-γ chain dodecapeptide as platelet substitutes in vitro and in vivo

Okamura, Y., Fujie, T., Handa, M., Ikeda, Y. & Takeoka, S., 2005 Dec 1, p. 4933-4934. 2 p.

Research output: Contribution to conferencePaper

Hemostatic effects of fibrinogen γ-chain dodecapeptide-conjugated polymerized albumin particles in vitro and in vivo

Okamura, Y., Takeoka, S., Teramura, Y., Maruyama, H., Tsuchida, E., Handa, M. & Ikeda, Y., 2005 Jul 1, In : Transfusion. 45, 7, p. 1221-1228 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Hemostatic effects of phospholipid vesicles carrying fibrinogen γ chain dodecapeptide in vitro and in vivo

Okamura, Y., Maekawa, I., Teramura, Y., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2005 Nov 1, In : Bioconjugate Chemistry. 16, 6, p. 1589-1596 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Improvement of oxygen carrying ability of hemoglobin vesicles by H 2O 2 elimination system

Atoji, T., Aihara, M., Takeoka, S. & Tsuchida, E., 2005 Dec 1, p. 4927-4928. 2 p.

Research output: Contribution to conferencePaper

Ligand exchange of hemoglobin vesicle with the model device optimized its light response to gas-liquid boundary face more efficient

Suzuki, D., Takeoka, S., Sou, K. & Tsuchida, E., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue

Contaldo, C., Plock, J., Sakai, H., Takeoka, S., Tsuchida, E., Leunig, M., Banic, A. & Erni, D., 2005 Apr 1, In : Critical Care Medicine. 33, 4, p. 806-812 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Oxygen infusions (hemoglobin-vesicles and albumin-hemes) based on nano-molecular sciences

Tsuchida, E., Sakai, H., Komatsu, T., Takeoka, S., Huang, Y., Sou, K., Nakagawa, A., Teramura, Y. & Kobayashi, K., 2005 Feb 1, In : Polymers for Advanced Technologies. 16, 2-3, p. 73-83 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution

Cabrales, P., Sakai, H., Tsai, A. G., Takeoka, S., Tsuchida, E. & Intaglietta, M., 2005 Apr 1, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 4 57-4, p. H1885-H1892

Research output: Contribution to journalArticle

45 Citations (Scopus)

Pharmacokinetics properties of surface-modified vesicles

Sou, K., Coins, B., Phillips, W. T., Takeoka, S. & Tsuchida, E., 2005 Dec 1, p. 3046-3047. 2 p.

Research output: Contribution to conferencePaper

Physiologic capacity of reticuloendothelial system for degradation of Hb-vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days

Sakai, H., Sou, K., Takeoka, S., Horinouchi, H., Kobayashi, K. & Tsuchida, E., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Porphyrin capped with calix[4]arene derivative via hydrogen bonds

Arai, S., Ohkawa, H., Ishihara, S., Shibue, T., Takeoka, S. & Nishide, H., 2005, In : Bulletin of the Chemical Society of Japan. 78, 11, p. 2007-2013 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Preparation of pH-responsive liposomes with aminolipids

Obata, Y. & Takeoka, S., 2005 Dec 1, p. 4943-4944. 2 p.

Research output: Contribution to conferencePaper

Redox property of 3-dithiolthione-substituted polythiophene and its membrane

Takemura, I., Utsunomiya, S., Takeoka, S. & Nishide, H., 2005 Dec 1. 1 p.

Research output: Contribution to conferencePaper

Self-assembly of porphyrins with uracil and melamine derivatives

Arai, S., Niwa, D., Takeoka, S. & Nishide, H., 2005 Dec 1, p. 4913-4914. 2 p.

Research output: Contribution to conferencePaper