• 1352 Citations
  • 21 h-Index
19972019
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Research Output 1997 2019

  • 1352 Citations
  • 21 h-Index
  • 56 Article
  • 2 Chapter
2019
1 Citation (Scopus)

DNA polymerase (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse

Wang, Z., Song, Y., Li, S., Kurian, S., Xiang, R., Chiba, T. & Wu, X., 2019 Jan 1, In : Journal of Biological Chemistry. 294, 11, p. 3909-3919 11 p.

Research output: Contribution to journalArticle

Oncology
Double-Stranded DNA Breaks
DNA-Directed DNA Polymerase
Joining
Repair
2 Citations (Scopus)

ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures

Li, S., Lu, H., Wang, Z., Hu, Q., Wang, H., Xiang, R., Chiba, T. & Wu, X., 2019 Jun 28, In : Food Science and Human Wellness. 16, p. 63-78 16 p.

Research output: Contribution to journalArticle

Open Access
Double-Stranded DNA Breaks
DNA repair
DNA
AT Rich Sequence
G-Quadruplexes
2015
6 Citations (Scopus)

Chronological analysis of caloric restriction-induced alteration of fatty acid biosynthesis in white adipose tissue of rats

Okita, N., Tsuchiya, T., Fukushima, M., Itakura, K., Yuguchi, K., Narita, T., Hashizume, Y., Sudo, Y., Chiba, T., Shimokawa, I. & Higami, Y., 2015 Mar 1, In : Experimental Gerontology. 63, p. 59-66 8 p.

Research output: Contribution to journalArticle

Caloric Restriction
White Adipose Tissue
Biosynthesis
Rats
Fatty Acids

Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect

Kamohara, R., Yamaza, H., Tsuchiya, T., Komatsu, T., Park, S., Hayashi, H., Chiba, T., Mori, R., Otabe, S., Yamada, K., Nagayasu, T. & Shimokawa, I., 2015 Apr 1, In : Experimental Gerontology. 64, p. 46-54 9 p.

Research output: Contribution to journalArticle

Physiological Stress
Adiponectin
Nutrition
Tumors
Genes
33 Citations (Scopus)

The life-extending effect of dietary restriction requires Foxo3 in mice

Shimokawa, I., Komatsu, T., Hayashi, N., Kim, S. E., Kawata, T., Park, S., Hayashi, H., Yamaza, H., Chiba, T. & Mori, R., 2015 Aug 1, In : Aging Cell. 14, 4, p. 707-709 3 p.

Research output: Contribution to journalArticle

Neoplasms
Forkhead Transcription Factors
11 Citations (Scopus)

Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction

Kim, S. E., Mori, R., Komatsu, T., Chiba, T., Hayashi, H., Park, S., Sugawa, M. D., Dencher, N. A. & Shimokawa, I., 2015 Jun 1, In : Age. 37, 3

Research output: Contribution to journalArticle

Electron Transport Complex IV
3T3 Cells
Oxidoreductases
Up-Regulation
NF-E2-Related Factor 2
2014
18 Citations (Scopus)

A key role for neuropeptide y in lifespan extension and cancer suppression via dietary restriction

Chiba, T., Tamashiro, Y., Park, D., Kusudo, T., Fujie, R., Komatsu, T., Kim, S. E., Park, S., Hayashi, H., Mori, R., Yamashita, H., Chung, H. Y. & Shimokawa, I., 2014 Mar 31, In : Scientific Reports. 4, 4517.

Research output: Contribution to journalArticle

Neuropeptide Y
Neuropeptides
Physiological Adaptation
Neoplasms
Physiological Phenomena
19 Citations (Scopus)

NPY antagonism reduces adiposity and attenuates age-related imbalance of adipose tissue metabolism

Park, S., Fujishita, C., Komatsu, T., Kim, S. E., Chiba, T., Mori, R. & Shimokawa, I., 2014 Dec 1, In : FASEB Journal. 28, 12, p. 5337-5348 12 p.

Research output: Contribution to journalArticle

Neuropeptide Y
Adiposity
Metabolism
Adipose Tissue
Tissue
2013
15 Citations (Scopus)

Caloric restriction-Associated remodeling of rat white adipose tissue: Effects on the growth hormone/insulin-like growth factor-1 axis, sterol regulatory element binding protein-1, and macrophage infiltration

Chujo, Y., Fujii, N., Okita, N., Konishi, T., Narita, T., Yamada, A., Haruyama, Y., Tashiro, K., Chiba, T., Shimokawa, I. & Higami, Y., 2013 Aug, In : Age. 35, 4, p. 1143-1156 14 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Caloric Restriction
White Adipose Tissue
Somatomedins
Growth Hormone

Food and Longevity Genes

Shimokawa, I. & Chiba, T., 2013, Bioactive Food as Dietary Interventions for the Aging Population. Elsevier Inc., p. 61-70 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Food
Genes
genes
2012
24 Citations (Scopus)

Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint

Lee, A. Y. L., Chiba, T., Truong, L. N., Cheng, A. N., Do, J., Cho, M. J., Chen, L. & Wu, X., 2012 Jan 20, In : Journal of Biological Chemistry. 287, 4, p. 2531-2543 13 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
Ataxia Telangiectasia
Phosphotransferases
Phosphorylation
Proteins
9 Citations (Scopus)

Protein reporter bioassay systems for the phenotypic screening of candidate drugs: A mouse platform for anti-aging drug screening

Chiba, T., Tsuchiya, T., Mori, R. & Shimokawa, I., 2012 Feb, In : Sensors. 12, 2, p. 1648-1656 9 p.

Research output: Contribution to journalArticle

bioassay
Preclinical Drug Evaluations
Bioassay
Drug Discovery
Biological Assay
2011
3 Citations (Scopus)

Acute stress response modified by modest inhibition of growth hormone axis: A potential machinery of the anti-aging effect of calorie restriction

Komatsu, T., Trindade, L. S., Chiba, T., Hayashi, H., Henmi, T., Ushiroda, Y., Mori, R. & Shimokawa, I., 2011 Mar, In : Mechanisms of Ageing and Development. 132, 3, p. 103-109 7 p.

Research output: Contribution to journalArticle

Growth Hormone
Insulin-Like Growth Factor I
Transgenic Rats
Acute-Phase Reaction
Transcription Factor AP-1
1 Citation (Scopus)

Down-regulation of hepatic AMP-activated protein kinase and up-regulation of CREB coactivator CRTC2 for gluconeogenesis under calorie-restricted conditions at a young age

Trindade, L. S., Park, S. J., Komatsu, T., Yamaza, H., Hayashi, H., Mori, R., Chiba, T., Shimokawa, I. & Kuramoto, K., 2011, In : Acta Medica Nagasakiensia. 55, 2, p. 85-92 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Gluconeogenesis
Up-Regulation
Down-Regulation
Sirolimus
2 Citations (Scopus)

Modest inhibition of the growth hormone axis does not affect mitochondrial reactive oxygen species generation or redox state, unlike calorie restriction

Hayashida, T., Komatsu, T., Henmi, Y., Yanagihara-Ota, K., Kim, A. R., Chiba, T., Goto, S., Chung, H. Y. & Shimokawa, I., 2011 Oct, In : Geriatrics and Gerontology International. 11, 4, p. 496-503 8 p.

Research output: Contribution to journalArticle

Growth Hormone
Oxidation-Reduction
Reactive Oxygen Species
Glutathione Disulfide
Liver
25 Citations (Scopus)

Release of TNF-α from macrophages is mediated by small GTPase Rab37

Mori, R., Ikematsu, K., Kitaguchi, T., Kim, S. E., Okamoto, M., Chiba, T., Miyawaki, A., Shimokawa, I. & Tsuboi, T., 2011 Nov, In : European Journal of Immunology. 41, 11, p. 3230-3239 10 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Macrophages
Skin
Small Interfering RNA
Membrane Fusion Proteins
2010
9 Citations (Scopus)

Development of a bioassay to screen for chemicals mimicking the anti-aging effects of calorie restriction

Chiba, T., Tsuchiya, T., Komatsu, T., Mori, R., Hayashi, H., Shimano, H., Spindler, S. R. & Shimokawa, I., 2010 Oct 15, In : Biochemical and Biophysical Research Communications. 401, 2, p. 213-218 6 p.

Research output: Contribution to journalArticle

Caloric Restriction
Bioassay
Biological Assay
Aging of materials
Hepatocyte Nuclear Factor 4
13 Citations (Scopus)

Development of calorie restriction mimetics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases

Chiba, T., Tsuchiya, T., Komatsu, T., Mori, R., Hayashi, H. & Shimokawa, I., 2010, In : Current Genomics. 11, 8, p. 562-567 6 p.

Research output: Contribution to journalArticle

Neurodegenerative Diseases
Obesity
Phytochemicals
Adipokines
Hunger
46 Citations (Scopus)

FoxO1 is involved in the antineoplastic effect of calorie restriction

Yamaza, H., Komatsu, T., Wakita, S., Kijogi, C., Park, S., Hayashi, H., Chiba, T., Mori, R., Furuyama, T., Mori, N. & Shimokawa, I., 2010 Jun, In : Aging Cell. 9, 3, p. 372-382 11 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Oxidative Stress
Genes
Body Weight Changes
Liver
29 Citations (Scopus)

SIRT1 regulates thyroid-stimulating hormone release by enhancing PIP5Kγ activity through deacetylation of specific lysine residues in mammals

Akieda-Asai, S., Zaima, N., Ikegami, K., Kahyo, T., Yao, I., Hatanaka, T., Iemura, S. I., Sugiyama, R., Yokozeki, T., Eishi, Y., Koike, M., Ikeda, K., Chiba, T., Yamaza, H., Shimokawa, I., Song, S. Y., Matsuno, A., Mizutani, A., Sawabe, M., Chao, M. V. & 8 others, Tanaka, M., Kanaho, Y., Natsume, T., Sugimura, H., Date, Y., Mcburney, M. W., Guarente, L. & Setou, M., 2010, In : PLoS One. 5, 7, e11755.

Research output: Contribution to journalArticle

thyrotropin
Mammals
phosphatidylinositols
Thyrotropin
Metabolism
2009
1 Citation (Scopus)

A transgenic dwarf rat strain as a tool for the study of immunosenescence in aging rats and the effect of calorie restriction

Shimokawa, I., Utsuyama, M., Komatsu, T., Yamaza, H. & Chiba, T., 2009, Handbook on Immunosenescence: Basic Understanding and Clinical Applications. Springer Netherlands, p. 131-144 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Transgenic Rats
Growth Hormone
Immune System
Lymphocyte Subsets
Laboratory Animals
4 Citations (Scopus)

Divergent regulation of adipose tissue metabolism by calorie restriction and inhibition of growth hormone signaling

Park, S., Komatsu, T., Hayashi, H., Trindade, L. S., Yamaza, H., Chiba, T. & Shimokawa, I., 2009 Oct, In : Experimental Gerontology. 44, 10, p. 646-652 7 p.

Research output: Contribution to journalArticle

Enzyme inhibition
Metabolism
Growth Hormone
Adipose Tissue
Rats
14 Citations (Scopus)

Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: Implications for longevity

Chiba, T., Inoue, D., Mizuno, A., Komatsu, T., Fujita, S., Kubota, H., Luisa Tagliaro, M., Park, S., Trindade, L. S., Hayashida, T., Hayashi, H., Yamaza, H., Higami, Y. & Shimokawa, I., 2009 Mar, In : Neurobiology of Aging. 30, 3, p. 474-482 9 p.

Research output: Contribution to journalArticle

Insulin Receptor Substrate Proteins
Hypothalamus
Brain
Insulin-Like Growth Factor I
Insulin
22 Citations (Scopus)

Similar metabolic responses to calorie restriction in lean and obese Zucker rats

Chiba, T., Komatsu, T., Nakayama, M., Adachi, T., Tamashiro, Y., Hayashi, H., Yamaza, H., Higami, Y. & Shimokawa, I., 2009 Oct 15, In : Molecular and Cellular Endocrinology. 309, 1-2, p. 17-25 9 p.

Research output: Contribution to journalArticle

Zucker Rats
Rats
Insulin
Neuropeptide Y
Insulin Resistance
2008
10 Citations (Scopus)

Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 2008 Dec, In : Age. 30, 4, p. 293-302 10 p.

Research output: Contribution to journalArticle

White Adipose Tissue
Protein Kinase C
Insulin
Glucose
Facilitative Glucose Transport Proteins
12 Citations (Scopus)

Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis

Hayashi, H., Yamaza, H., Komatsu, T., Park, S., Chiba, T., Higami, Y., Nagayasu, T. & Shimokawa, I., 2008 Sep, In : Experimental Gerontology. 43, 9, p. 827-832 6 p.

Research output: Contribution to journalArticle

Quadriceps Muscle
Somatomedins
Growth Hormone
Rats
Chemical activation
34 Citations (Scopus)

Longevity genes: Insights from calorie restriction and genetic longevity models

Shimokawa, I., Chiba, T., Yamaza, H. & Komatsu, T., 2008 Nov 30, In : Molecules and Cells. 26, 5, p. 427-435 9 p.

Research output: Contribution to journalArticle

Genetic Models
Genes
Somatomedins
Food
Growth Hormone
43 Citations (Scopus)

Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8

Komatsu, T., Chiba, T., Yamaza, H., Yamashita, K., Shimada, A., Hoshiyama, Y., Henmi, T., Ohtani, H., Higami, Y., de Cabo, R., Ingram, D. K. & Shimokawa, I., 2008 Apr, In : Experimental Gerontology. 43, 4, p. 339-346 8 p.

Research output: Contribution to journalArticle

Nutrition
Learning
Diet
Data storage equipment
Chemical analysis
21 Citations (Scopus)

Pituitary growth hormone suppression reduces resistin expression and enhances insulin effectiveness: Relationship with caloric restriction

Chiba, T., Yamaza, H., Komatsu, T., Nakayama, M., Fujita, S., Hayashi, H., Higami, Y. & Shimokawa, I., 2008 Jun, In : Experimental Gerontology. 43, 6, p. 595-600 6 p.

Research output: Contribution to journalArticle

Resistin
Caloric Restriction
Growth Hormone
Insulin
Insulin-Like Growth Factor I
2007
32 Citations (Scopus)

Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver

To, K., Yamaza, H., Komatsu, T., Hayashida, T., Hayashi, H., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 2007 Nov, In : Experimental Gerontology. 42, 11, p. 1063-1071 9 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Liver
Rats
Down-Regulation
Quadriceps Muscle
10 Citations (Scopus)

Identification of differentially expressed genes in senescence-accelerated mouse testes by suppression subtractive hybridization analysis

Chiba, T., Yao, J., Higami, Y., Shimokawa, I., Hosokawa, M. & Higuchi, K., 2007 Feb, In : Mammalian Genome. 18, 2, p. 105-112 8 p.

Research output: Contribution to journalArticle

Testis
Down-Regulation
Spermatogenesis
Genes
Cyclic AMP Response Element Modulator
7 Citations (Scopus)

Identification of fasting-induced genes in the rat hypothalamus: Relationship with neuroprotection

Chiba, T., Fujita, S., Kubota, H., Inoue, D., Mizuno, A., Komatsu, T., Yamaza, H., Higami, Y. & Shimokawa, I., 2007 Nov, In : Annals of the New York Academy of Sciences. 1119, 1, p. 216-226 11 p.

Research output: Contribution to journalArticle

Hypothalamus
Rats
Fasting
Cell Death
Genes
29 Citations (Scopus)

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: Regulation of plasma adiponectin and leptin

Yamaza, H., Komatsu, T., To, K., Toyama, H., Chiba, T., Higami, Y. & Shimokawa, I., 2007 Jan, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 62, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

Caloric Restriction
Adiponectin
Somatomedins
Leptin
Transgenic Rats
13 Citations (Scopus)
Insulin-Like Growth Factor I
Growth Hormone
Rodentia
Insulin
Caloric Restriction
55 Citations (Scopus)

The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted

Liu, E., Lee, A. Y. L., Chiba, T., Olson, E., Sun, P. & Wu, X., 2007 Nov 19, In : Journal of Cell Biology. 179, 4, p. 643-657 15 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
Ataxia Telangiectasia
Licensure
Single-Stranded DNA
DNA
2006
17 Citations (Scopus)

Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle

Park, S., Komatsu, T., Hayashi, H., Yamaza, H., Chiba, T., Higami, Y., Kuramoto, K. & Shimokawa, I., 2006 Sep, In : Experimental Gerontology. 41, 9, p. 837-845 9 p.

Research output: Contribution to journalArticle

Muscle
Rats
Skeletal Muscle
Insulin
Glucose
13 Citations (Scopus)

Effect of leptin on hypothalamic gene expression in calorie-restricted rats

Komatsu, T., Chiba, T., Yamaza, H., To, K., Toyama, H., Higami, Y. & Shimokawa, I., 2006 Sep, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 9, p. 890-898 9 p.

Research output: Contribution to journalArticle

Leptin
Arcuate Nucleus of Hypothalamus
Gene Expression
Agouti-Related Protein
Neuropeptide Y
20 Citations (Scopus)

Hepatic gene expression profile of lipid metabolism in rats: Impact of caloric restriction and growth hormone/insulin-like growth factor-1 suppression

Higami, Y., Tsuchiya, T., Chiba, T., Yamaza, H., Muraoka, I., Hirose, M., Komatsu, T. & Shimokawa, I., 2006 Nov, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 11, p. 1099-1110 12 p.

Research output: Contribution to journalArticle

Caloric Restriction
Somatomedins
Transcriptome
Lipid Metabolism
Growth Hormone
2005
17 Citations (Scopus)

Acute stress response in calorie-restricted rats to lipopolysaccharide- induced inflammation

Tsuchiya, T., Higami, Y., Komatsu, T., Tanaka, K., Honda, S., Yamaza, H., Chiba, T., Ayabe, H. & Shimokawa, I., 2005 May, In : Mechanisms of Ageing and Development. 126, 5, p. 568-579 12 p.

Research output: Contribution to journalArticle

Liver
Lipopolysaccharides
Rats
Genes
Inflammation
2004
26 Citations (Scopus)

A transgenic dwarf rat model as a tool for the study of calorie restriction and aging

Yamaza, H., Komatsu, T., Chiba, T., Toyama, H., To, K., Higami, Y. & Shimokawa, I., 2004 Feb, In : Experimental Gerontology. 39, 2, p. 269-272 4 p.

Research output: Contribution to journalArticle

Transgenic Rats
Rats
Aging of materials
Insulin
Transgenes
6 Citations (Scopus)

Expression of DNase gamma during Fas-independent apoptotic DNA fragmentation in rodent hepatocytes

Higami, Y., Tsuchiya, T., To, K., Chiba, T., Yamaza, H., Shiokawa, D., Tanuma, S. I. & Shimokawa, I., 2004 Jun, In : Cell and Tissue Research. 316, 3, p. 403-407 5 p.

Research output: Contribution to journalArticle

Deoxyribonucleases
DNA Fragmentation
Hepatocytes
Rodentia
DNA
16 Citations (Scopus)

Mouse testis transcriptome reveled using serial analysis of gene expression

Yao, J., Chiba, T., Sakai, J., Hirose, K., Yamamoto, M., Hada, A., Kuramoto, K., Higuchi, K. & Mori, M., 2004 Jun, In : Mammalian Genome. 15, 6, p. 433-451 19 p.

Research output: Contribution to journalArticle

Transcriptome
Testis
Gene Expression
Seminiferous Epithelium
Oligospermia
69 Citations (Scopus)

SV40 T antigen interacts with Nbs1 to disrupt DNA replication control

Wu, X., Avni, D., Chiba, T., Yan, F., Zhao, Q., Lin, Y., Heng, H. & Livingston, D., 2004 Jun 1, In : Genes and Development. 18, 11, p. 1305-1316 12 p.

Research output: Contribution to journalArticle

Nijmegen Breakage Syndrome
Simian virus 40
Viral Tumor Antigens
DNA Replication
Chromosomal Instability
2003
20 Citations (Scopus)

Effects of caloric restriction on gene expression in the arcuate nucleus

Shimokawa, I., Fukuyama, T., Yanagihara-Outa, K., Tomita, M., Komatsu, T., Higami, Y., Tuchiya, T., Chiba, T. & Yamaza, Y., 2003 Jan, In : Neurobiology of Aging. 24, 1, p. 117-123 7 p.

Research output: Contribution to journalArticle

Caloric Restriction
Arcuate Nucleus of Hypothalamus
Gene Expression
Cyclophilins
Growth Hormone-Releasing Hormone
93 Citations (Scopus)

Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction.

Shimokawa, I., Higami, Y., Tsuchiya, T., Otani, H., Komatsu, T., Chiba, T. & Yamaza, H., 2003, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1108-1109 2 p.

Research output: Contribution to journalArticle

Caloric Restriction
Somatomedins
Life Expectancy
Growth Hormone
Transgenes
2002
47 Citations (Scopus)

Anti-aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling

Chiba, T., Yamaza, H., Higami, Y. & Shimokawa, I., 2002 Nov 15, In : Microscopy Research and Technique. 59, 4, p. 317-324 8 p.

Research output: Contribution to journalArticle

anti-aging properties
Caloric Restriction
leptin
adipose tissues
adipose tissue
25 Citations (Scopus)

Lifespan extension by caloric restriction: An aspect of energy metabolism

Yamaza, H., Chiba, T., Higami, Y. & Shimokawa, I., 2002 Nov 15, In : Microscopy Research and Technique. 59, 4, p. 325-330 6 p.

Research output: Contribution to journalArticle

Caloric Restriction
gluconeogenesis
gene silencing
metabolism
energy metabolism
91 Citations (Scopus)

Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model

Shimokawa, I., Higami, Y., Utsuyama, M., Tuchiya, T., Komatsu, T., Chiba, T. & Yamaza, H., 2002, In : American Journal of Pathology. 160, 6, p. 2259-2265 7 p.

Research output: Contribution to journalArticle

Transgenic Rats
Somatomedins
Life Expectancy
Growth Hormone
Transgenes
2001
14 Citations (Scopus)

Extrahepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis

Fu, L., Matsuyama, I., Chiba, T., Xing, Y., Korenaga, T., Guo, Z., Fu, X., Nakayama, J., Mori, M. & Higuchi, K., 2001, In : Journal of Histochemistry and Cytochemistry. 49, 6, p. 739-747 9 p.

Research output: Contribution to journalArticle

Apolipoprotein A-II
Amyloidosis
Amyloid
Messenger RNA
Epithelial Cells
85 Citations (Scopus)

Transmission of mouse senile amyloidosis

Xing, Y., Nakamura, A., Chiba, T., Kogishi, K., Matsushita, T., Li, F., Guo, Z., Hosokawa, M., Mori, M. & Higuchi, K., 2001, In : Laboratory Investigation. 81, 4, p. 493-499 7 p.

Research output: Contribution to journalArticle

Amyloidosis
Amyloid
Apolipoproteins A
Feces
Amyloid Plaques