3D-Printable Biodegradable Polyester Tissue Scaffolds for Cell Adhesion

Justin M. Sirrine, Allison M. Pekkanen, Ashley M. Nelson, Nicholas A. Chartrain, Christopher B. Williams, Timothy Edward Long

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Additive manufacturing, or three-dimensional (3D) printing, has emerged as a viable technique for the production of vascularized tissue engineering scaffolds. In this report, a biocompatible and biodegradable poly(tri(ethylene glycol) adipate) dimethacrylate was synthesized and characterized for suitability in soft-tissue scaffolding applications. The polyester dimethacrylate exhibited highly efficient photocuring, hydrolyzability, and 3D printability in a custom microstereolithography system. The photocured polyester film demonstrated significantly improved cell attachment and viability as compared with controls. These results indicate promise of novel, printable polyesters for 3D patterned, vascularized soft-tissue engineering scaffolds.

Original languageEnglish
Pages (from-to)1409-1414
Number of pages6
JournalAustralian Journal of Chemistry
Volume68
Issue number9
DOIs
Publication statusPublished - 2015 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Sirrine, J. M., Pekkanen, A. M., Nelson, A. M., Chartrain, N. A., Williams, C. B., & Long, T. E. (2015). 3D-Printable Biodegradable Polyester Tissue Scaffolds for Cell Adhesion. Australian Journal of Chemistry, 68(9), 1409-1414. https://doi.org/10.1071/CH15327