A case of anorexia nervosa with severe liver dysfunction and pancytopenia

M. Sakuramoto, M. Ohbayashi, M. Shimura, Shinobu Nomura, T. Kuboki, H. Suematsu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 18 year old girl was admitted to our hospital due to anorexia nervosa (AN) in March 1993. She hardly ate anything, and lost her weight from 27.8 kg to 25.8 kg in 10 days. On 15th day, she suffered from severe liver dysfunction due to malnutrition. On 21th day, GOT, GPT, LDH and ALP rose to 4,210 U/l, 2,482 U/l, 2,448 U/l and 1,920 U/l respectively. At the same time she showed pancytopenia. Peripheral WBC and Hb were reduced to 1,400/mm3 and 7.1 g/l respectively, indicating normochromic normocytic anemia. Platelet was also reduced to 2.9 x 104/mm3, but prothrombin time and active partial thromboplastin time were normal. She was treated with mainly intravenous hyperalimentation (IVH), then she recovered after about two months. Thereafter she was treated with combination of behavior therapy and psychotherapy and discharged after five months. AN sometimes complicates liver dysfunction, but a severe case is rare. We investigated some hypotheses of this mechanism referring to previous reports about severe liver dysfunction with AN. And we discussed the relationship between liver dysfunction and pancytopenia.

Original languageEnglish
Pages (from-to)291-296
Number of pages6
JournalJapanese Journal of Psychosomatic Medicine
Volume37
Issue number4
Publication statusPublished - 1997
Externally publishedYes

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Pancytopenia
Anorexia Nervosa
Liver Diseases
Partial Thromboplastin Time
Total Parenteral Nutrition
Behavior Therapy
Prothrombin Time
Malnutrition
Psychotherapy
Anemia
Blood Platelets
Weights and Measures

Keywords

  • anorexia nervosa
  • liver dysfunction
  • pancytopenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Sakuramoto, M., Ohbayashi, M., Shimura, M., Nomura, S., Kuboki, T., & Suematsu, H. (1997). A case of anorexia nervosa with severe liver dysfunction and pancytopenia. Japanese Journal of Psychosomatic Medicine, 37(4), 291-296.

A case of anorexia nervosa with severe liver dysfunction and pancytopenia. / Sakuramoto, M.; Ohbayashi, M.; Shimura, M.; Nomura, Shinobu; Kuboki, T.; Suematsu, H.

In: Japanese Journal of Psychosomatic Medicine, Vol. 37, No. 4, 1997, p. 291-296.

Research output: Contribution to journalArticle

Sakuramoto, M, Ohbayashi, M, Shimura, M, Nomura, S, Kuboki, T & Suematsu, H 1997, 'A case of anorexia nervosa with severe liver dysfunction and pancytopenia', Japanese Journal of Psychosomatic Medicine, vol. 37, no. 4, pp. 291-296.
Sakuramoto M, Ohbayashi M, Shimura M, Nomura S, Kuboki T, Suematsu H. A case of anorexia nervosa with severe liver dysfunction and pancytopenia. Japanese Journal of Psychosomatic Medicine. 1997;37(4):291-296.
Sakuramoto, M. ; Ohbayashi, M. ; Shimura, M. ; Nomura, Shinobu ; Kuboki, T. ; Suematsu, H. / A case of anorexia nervosa with severe liver dysfunction and pancytopenia. In: Japanese Journal of Psychosomatic Medicine. 1997 ; Vol. 37, No. 4. pp. 291-296.
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