A high-resolution passive droplet-phase sample sorter using multi-stage droplet transfer

Donghyun Yoon; Z. Xie; Daiki Tanaka; Tetsushi Sekiguchi; Shuichi Shoji

doi:10.1039/c7ra05556k

A high-resolution passive droplet-phase sample sorter using multi-stage droplet transfer

Donghyun Yoon, Z. Xie, Daiki Tanaka, Tetsushi Sekiguchi, Shuichi Shoji

Research Organization for Nano & Life Innovation

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

A fully passive volume-dependent droplet sorter is presented in this research. Repeated and multiple on-rail transfer of microdroplets in a cascade channel resulted in high resolution sorting of droplet-phase samples. Microdroplets with volumes of 0.89-3.26 nl were successfully sorted in eight steps, and a maximum sorting resolution of about 0.21 nl was obtained over three transfer stages. Line rails and dot rails employed in the cascading channels allowed volume-dependent droplet transfer, and shape recovery of the transferred droplet for the repeatable transfer, respectively. This simple device and method can be applied to droplet-based chemical or biological research.

Original language	English
Pages (from-to)	36750-36754
Number of pages	5
Journal	RSC Advances
Volume	7
Issue number	58
DOIs	https://doi.org/10.1039/c7ra05556k
Publication status	Published - 2017

Fingerprint

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

Cite this

Yoon, D., Xie, Z., Tanaka, D., Sekiguchi, T., & Shoji, S. (2017). A high-resolution passive droplet-phase sample sorter using multi-stage droplet transfer. RSC Advances, 7(58), 36750-36754. https://doi.org/10.1039/c7ra05556k

@article{e59bf9e90bc64b2d83b6c135b04b7e5b,

title = "A high-resolution passive droplet-phase sample sorter using multi-stage droplet transfer",

abstract = "A fully passive volume-dependent droplet sorter is presented in this research. Repeated and multiple on-rail transfer of microdroplets in a cascade channel resulted in high resolution sorting of droplet-phase samples. Microdroplets with volumes of 0.89-3.26 nl were successfully sorted in eight steps, and a maximum sorting resolution of about 0.21 nl was obtained over three transfer stages. Line rails and dot rails employed in the cascading channels allowed volume-dependent droplet transfer, and shape recovery of the transferred droplet for the repeatable transfer, respectively. This simple device and method can be applied to droplet-based chemical or biological research.",

author = "Donghyun Yoon and Z. Xie and Daiki Tanaka and Tetsushi Sekiguchi and Shuichi Shoji",

year = "2017",

doi = "10.1039/c7ra05556k",

language = "English",

volume = "7",

pages = "36750--36754",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "58",

}

TY - JOUR

T1 - A high-resolution passive droplet-phase sample sorter using multi-stage droplet transfer

AU - Yoon, Donghyun

AU - Xie, Z.

AU - Tanaka, Daiki

AU - Sekiguchi, Tetsushi

AU - Shoji, Shuichi

PY - 2017

Y1 - 2017

N2 - A fully passive volume-dependent droplet sorter is presented in this research. Repeated and multiple on-rail transfer of microdroplets in a cascade channel resulted in high resolution sorting of droplet-phase samples. Microdroplets with volumes of 0.89-3.26 nl were successfully sorted in eight steps, and a maximum sorting resolution of about 0.21 nl was obtained over three transfer stages. Line rails and dot rails employed in the cascading channels allowed volume-dependent droplet transfer, and shape recovery of the transferred droplet for the repeatable transfer, respectively. This simple device and method can be applied to droplet-based chemical or biological research.

AB - A fully passive volume-dependent droplet sorter is presented in this research. Repeated and multiple on-rail transfer of microdroplets in a cascade channel resulted in high resolution sorting of droplet-phase samples. Microdroplets with volumes of 0.89-3.26 nl were successfully sorted in eight steps, and a maximum sorting resolution of about 0.21 nl was obtained over three transfer stages. Line rails and dot rails employed in the cascading channels allowed volume-dependent droplet transfer, and shape recovery of the transferred droplet for the repeatable transfer, respectively. This simple device and method can be applied to droplet-based chemical or biological research.

UR - http://www.scopus.com/inward/record.url?scp=85026345981&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026345981&partnerID=8YFLogxK

U2 - 10.1039/c7ra05556k

DO - 10.1039/c7ra05556k

M3 - Article

AN - SCOPUS:85026345981

VL - 7

SP - 36750

EP - 36754

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 58

ER -

Access to Document

10.1039/c7ra05556k