A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation.

Xiaowei Lu, Mariko Tsukune, Hiroki Watanabe, Nozomu Yamazaki, Yosuke Isobe, Y. Kobayashi, Tomoyuki Miyashita, Masakatsu G. Fujie

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.

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Viscoelasticity
Ablation
Coagulation
Radio
Liver
Tissue
Temperature
Rheometers
Liver Neoplasms
Least-Squares Analysis
Mean square error
Needles
Data acquisition
Electrodes
Imaging techniques

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

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title = "A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation.",
abstract = "Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.",
author = "Xiaowei Lu and Mariko Tsukune and Hiroki Watanabe and Nozomu Yamazaki and Yosuke Isobe and Y. Kobayashi and Tomoyuki Miyashita and Fujie, {Masakatsu G.}",
year = "2012",
language = "English",
volume = "2012",
pages = "187--190",
journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",
issn = "1557-170X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

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TY - JOUR

T1 - A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation.

AU - Lu, Xiaowei

AU - Tsukune, Mariko

AU - Watanabe, Hiroki

AU - Yamazaki, Nozomu

AU - Isobe, Yosuke

AU - Kobayashi, Y.

AU - Miyashita, Tomoyuki

AU - Fujie, Masakatsu G.

PY - 2012

Y1 - 2012

N2 - Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.

AB - Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.

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