A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation

Xiaowei Lu, Mariko Tsukune, Hiroki Watanabe, Nozomu Yamazaki, Yosuke Isobe, Yo Kobayashi, Tomoyuki Miyashita, Masakatsu G. Fujie

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.

    Original languageEnglish
    Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
    Pages187-190
    Number of pages4
    DOIs
    Publication statusPublished - 2012
    Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA
    Duration: 2012 Aug 282012 Sep 1

    Other

    Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
    CitySan Diego, CA
    Period12/8/2812/9/1

    Fingerprint

    Viscoelasticity
    Ablation
    Coagulation
    Radio
    Liver
    Tissue
    Temperature
    Rheometers
    Liver Neoplasms
    Least-Squares Analysis
    Mean square error
    Needles
    Data acquisition
    Electrodes
    Imaging techniques

    ASJC Scopus subject areas

    • Computer Vision and Pattern Recognition
    • Signal Processing
    • Biomedical Engineering
    • Health Informatics

    Cite this

    Lu, X., Tsukune, M., Watanabe, H., Yamazaki, N., Isobe, Y., Kobayashi, Y., ... Fujie, M. G. (2012). A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 187-190). [6345902] https://doi.org/10.1109/EMBC.2012.6345902

    A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation. / Lu, Xiaowei; Tsukune, Mariko; Watanabe, Hiroki; Yamazaki, Nozomu; Isobe, Yosuke; Kobayashi, Yo; Miyashita, Tomoyuki; Fujie, Masakatsu G.

    Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. p. 187-190 6345902.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Lu, X, Tsukune, M, Watanabe, H, Yamazaki, N, Isobe, Y, Kobayashi, Y, Miyashita, T & Fujie, MG 2012, A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS., 6345902, pp. 187-190, 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012, San Diego, CA, 12/8/28. https://doi.org/10.1109/EMBC.2012.6345902
    Lu X, Tsukune M, Watanabe H, Yamazaki N, Isobe Y, Kobayashi Y et al. A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. p. 187-190. 6345902 https://doi.org/10.1109/EMBC.2012.6345902
    Lu, Xiaowei ; Tsukune, Mariko ; Watanabe, Hiroki ; Yamazaki, Nozomu ; Isobe, Yosuke ; Kobayashi, Yo ; Miyashita, Tomoyuki ; Fujie, Masakatsu G. / A method for deriving the coagulation boundary of liver tissue using a relational model of viscoelasticity and temperature in radio frequency ablation. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2012. pp. 187-190
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    abstract = "Recently radiofrequency (RF) ablation has become increasingly important in treating liver cancers. RF ablation is ordinarily conducted using elastographic imaging to monitor the ablation procedure and the temperature of the electrode needle is displayed on the RF generator. However, the coagulation boundary of liver tissue in RF ablation is unclear and unconfident. This can lead to both excessive and insufficient RF ablation thereby diminishing the advantages of the procedure. In the present study, we developed a method for determining the coagulation boundary of liver tissue in RF ablation. To investigate this boundary we used the mechanical characteristics of biochemical components as an indicator of coagulation to produce a relational model for viscoelasticity and temperature. This paper presents the data acquisition procedures for the viscoelasticity characteristics and the analytical method used for the coagulation model. We employed a rheometer to measure the viscoelastic characteristics of liver tissue. To determine the model functional relationship between viscoelasticity and temperature, we used a least-square method and the minimum root mean square error was calculated to optimize the model functional relations. The functional relation between temperature and viscoelasticity was linear and non-linear in different temperature regions. The boundary between linear and non-linear functional relation was 58.0°C.",
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    AU - Yamazaki, Nozomu

    AU - Isobe, Yosuke

    AU - Kobayashi, Yo

    AU - Miyashita, Tomoyuki

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