A miniature intraventricular axial flow blood pump that is introduced through the left ventricular apex

K. Yamazaki, Mitsuo Umezu, H. Koyanagi, M. Kitamura, K. Eishi, A. Kawai, O. Tagusari, H. Niinami, T. Akimoto, C. Nojiri, K. Tsuchiya, T. Mori, H. Iiyama, M. Endo

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A new intraventricular axial flow blood pump has been designed and developed as an implantable left ventricular assist device (LVAD). The pump consists of a tube housing (10 cm in length and 14 mm in diameter), a three-vane impeller combined with a guide vane, and a DC motor. This pump is introduced into the LV cavity through the LV apex, and the outlet cannula is passed antegrade across the aortic valve. Blood is withdrawn from the LV through the inlet ports at the pump base, and discharged into the ascending aorta. A pump flow of >8 L/min was obtained against 90 mmHg differential pressure in the mock circulatory system. In an acute dog model, this pump could produce a sufficient output of 200 ml/kg/min. In addition, the pump flow profile demonstrated a pulsatile pattern, although the rotation speed was fixed. This is mainly due to the changes in flow rate during a cardiac cycle-that is, during systole, the flow rate increases to the maximum, while the differential pressure between the LV and the aorta decreases to the minimum. Thus, this simple and compact axial flow blood pump can be a potential LVAD, with prompt accessibility and need for less invasive surgical procedures.

Original languageEnglish
JournalASAIO Journal
Volume38
Issue number3
Publication statusPublished - 1992
Externally publishedYes

Fingerprint

Axial flow
Heart-Assist Devices
Blood
Pumps
Aorta
Pressure
Systole
Left ventricular assist devices
Cardiovascular System
Aortic Valve
Dogs
Flow rate
DC motors

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering

Cite this

Yamazaki, K., Umezu, M., Koyanagi, H., Kitamura, M., Eishi, K., Kawai, A., ... Endo, M. (1992). A miniature intraventricular axial flow blood pump that is introduced through the left ventricular apex. ASAIO Journal, 38(3).

A miniature intraventricular axial flow blood pump that is introduced through the left ventricular apex. / Yamazaki, K.; Umezu, Mitsuo; Koyanagi, H.; Kitamura, M.; Eishi, K.; Kawai, A.; Tagusari, O.; Niinami, H.; Akimoto, T.; Nojiri, C.; Tsuchiya, K.; Mori, T.; Iiyama, H.; Endo, M.

In: ASAIO Journal, Vol. 38, No. 3, 1992.

Research output: Contribution to journalArticle

Yamazaki, K, Umezu, M, Koyanagi, H, Kitamura, M, Eishi, K, Kawai, A, Tagusari, O, Niinami, H, Akimoto, T, Nojiri, C, Tsuchiya, K, Mori, T, Iiyama, H & Endo, M 1992, 'A miniature intraventricular axial flow blood pump that is introduced through the left ventricular apex', ASAIO Journal, vol. 38, no. 3.
Yamazaki, K. ; Umezu, Mitsuo ; Koyanagi, H. ; Kitamura, M. ; Eishi, K. ; Kawai, A. ; Tagusari, O. ; Niinami, H. ; Akimoto, T. ; Nojiri, C. ; Tsuchiya, K. ; Mori, T. ; Iiyama, H. ; Endo, M. / A miniature intraventricular axial flow blood pump that is introduced through the left ventricular apex. In: ASAIO Journal. 1992 ; Vol. 38, No. 3.
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