A nano-fibrous assembly of collagen-hyaluronic acid for controlling cell-adhesive properties

Toshinori Fujie, Sho Furutate, Daisuke Niwa, Shinji Takeoka

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We report an artificially fabricated extracellular matrix (ECM)-like nanostructure, which utilizes self-assembly of collagen and hyaluronic acid in a quasi two-dimensional space of tens-of-nm thickness, displaying different cellular adhesive characteristics depending on the structural properties between the fibril and non-fibril elements. This nano-fibrous assembly will facilitate a mechano-biological approach for the development of tissue-engineering scaffolds.

Original languageEnglish
Pages (from-to)4672-4676
Number of pages5
JournalSoft Matter
Volume6
Issue number19
DOIs
Publication statusPublished - 2010 Oct 7

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

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