A novel method to develop an animal model of depression using a small mobile robot

Hiroyuki Ishii, Qing Shi, Shogo Fumino, Shinichiro Konno, Shinichi Kinoshita, Satoshi Okabayashi, Naritoshi Iida, Hiroshi Kimura, Yu Tahara, Shigenobu Shibata, Atsuo Takanishi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Robotics is contributing to studies on animal behavior. Mobile robots are actually used as devices to give external stimulus to animals in several experiments. We consider that this approach can be applied to studies in psychic medicine. In psychic medicine, all new drugs are evaluated in experiments using animal models of mental disorder before using it in clinical practice. However, conventional animal models have some problems in the construct validity. The animal models should be developed through the method which is consistently associated with the theory of the mental disorders while many of conventional models had been developed by genetic manipulations or surgical operations on nerve system. We considered that a novel animal model could be developed by stress exposure using a small mobile robot. We then implemented this method to the experimental system which had been developed in our past study. An experiment was conducted using the system, and the method was then verified. Therefore, we conclude that the animal model of depression developed by proposed method, exposing continuous attack by the robot in immature period and interactive attack in mature period, can be a novel animal model of depression.

Original languageEnglish
Pages (from-to)61-69
Number of pages9
JournalAdvanced Robotics
Volume27
Issue number1
DOIs
Publication statusPublished - 2013 Jan 1

Fingerprint

Mobile robots
Animals
Medicine
Experiments
Robotics
Robots

Keywords

  • animal behavior and mental disorder
  • bio-inspired design
  • mobile robot

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Human-Computer Interaction
  • Computer Science Applications
  • Hardware and Architecture
  • Software

Cite this

A novel method to develop an animal model of depression using a small mobile robot. / Ishii, Hiroyuki; Shi, Qing; Fumino, Shogo; Konno, Shinichiro; Kinoshita, Shinichi; Okabayashi, Satoshi; Iida, Naritoshi; Kimura, Hiroshi; Tahara, Yu; Shibata, Shigenobu; Takanishi, Atsuo.

In: Advanced Robotics, Vol. 27, No. 1, 01.01.2013, p. 61-69.

Research output: Contribution to journalArticle

Ishii, H, Shi, Q, Fumino, S, Konno, S, Kinoshita, S, Okabayashi, S, Iida, N, Kimura, H, Tahara, Y, Shibata, S & Takanishi, A 2013, 'A novel method to develop an animal model of depression using a small mobile robot', Advanced Robotics, vol. 27, no. 1, pp. 61-69. https://doi.org/10.1080/01691864.2013.752319
Ishii, Hiroyuki ; Shi, Qing ; Fumino, Shogo ; Konno, Shinichiro ; Kinoshita, Shinichi ; Okabayashi, Satoshi ; Iida, Naritoshi ; Kimura, Hiroshi ; Tahara, Yu ; Shibata, Shigenobu ; Takanishi, Atsuo. / A novel method to develop an animal model of depression using a small mobile robot. In: Advanced Robotics. 2013 ; Vol. 27, No. 1. pp. 61-69.
@article{9b3e214977c54905b12d8041b693ded9,
title = "A novel method to develop an animal model of depression using a small mobile robot",
abstract = "Robotics is contributing to studies on animal behavior. Mobile robots are actually used as devices to give external stimulus to animals in several experiments. We consider that this approach can be applied to studies in psychic medicine. In psychic medicine, all new drugs are evaluated in experiments using animal models of mental disorder before using it in clinical practice. However, conventional animal models have some problems in the construct validity. The animal models should be developed through the method which is consistently associated with the theory of the mental disorders while many of conventional models had been developed by genetic manipulations or surgical operations on nerve system. We considered that a novel animal model could be developed by stress exposure using a small mobile robot. We then implemented this method to the experimental system which had been developed in our past study. An experiment was conducted using the system, and the method was then verified. Therefore, we conclude that the animal model of depression developed by proposed method, exposing continuous attack by the robot in immature period and interactive attack in mature period, can be a novel animal model of depression.",
keywords = "animal behavior and mental disorder, bio-inspired design, mobile robot",
author = "Hiroyuki Ishii and Qing Shi and Shogo Fumino and Shinichiro Konno and Shinichi Kinoshita and Satoshi Okabayashi and Naritoshi Iida and Hiroshi Kimura and Yu Tahara and Shigenobu Shibata and Atsuo Takanishi",
year = "2013",
month = "1",
day = "1",
doi = "10.1080/01691864.2013.752319",
language = "English",
volume = "27",
pages = "61--69",
journal = "Advanced Robotics",
issn = "0169-1864",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

TY - JOUR

T1 - A novel method to develop an animal model of depression using a small mobile robot

AU - Ishii, Hiroyuki

AU - Shi, Qing

AU - Fumino, Shogo

AU - Konno, Shinichiro

AU - Kinoshita, Shinichi

AU - Okabayashi, Satoshi

AU - Iida, Naritoshi

AU - Kimura, Hiroshi

AU - Tahara, Yu

AU - Shibata, Shigenobu

AU - Takanishi, Atsuo

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Robotics is contributing to studies on animal behavior. Mobile robots are actually used as devices to give external stimulus to animals in several experiments. We consider that this approach can be applied to studies in psychic medicine. In psychic medicine, all new drugs are evaluated in experiments using animal models of mental disorder before using it in clinical practice. However, conventional animal models have some problems in the construct validity. The animal models should be developed through the method which is consistently associated with the theory of the mental disorders while many of conventional models had been developed by genetic manipulations or surgical operations on nerve system. We considered that a novel animal model could be developed by stress exposure using a small mobile robot. We then implemented this method to the experimental system which had been developed in our past study. An experiment was conducted using the system, and the method was then verified. Therefore, we conclude that the animal model of depression developed by proposed method, exposing continuous attack by the robot in immature period and interactive attack in mature period, can be a novel animal model of depression.

AB - Robotics is contributing to studies on animal behavior. Mobile robots are actually used as devices to give external stimulus to animals in several experiments. We consider that this approach can be applied to studies in psychic medicine. In psychic medicine, all new drugs are evaluated in experiments using animal models of mental disorder before using it in clinical practice. However, conventional animal models have some problems in the construct validity. The animal models should be developed through the method which is consistently associated with the theory of the mental disorders while many of conventional models had been developed by genetic manipulations or surgical operations on nerve system. We considered that a novel animal model could be developed by stress exposure using a small mobile robot. We then implemented this method to the experimental system which had been developed in our past study. An experiment was conducted using the system, and the method was then verified. Therefore, we conclude that the animal model of depression developed by proposed method, exposing continuous attack by the robot in immature period and interactive attack in mature period, can be a novel animal model of depression.

KW - animal behavior and mental disorder

KW - bio-inspired design

KW - mobile robot

UR - http://www.scopus.com/inward/record.url?scp=84873733364&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873733364&partnerID=8YFLogxK

U2 - 10.1080/01691864.2013.752319

DO - 10.1080/01691864.2013.752319

M3 - Article

AN - SCOPUS:84873733364

VL - 27

SP - 61

EP - 69

JO - Advanced Robotics

JF - Advanced Robotics

SN - 0169-1864

IS - 1

ER -