A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma, Yoshiaki Takei, Atsushi Murata, Takafumi Inoue, Shinji Takeoka

    Research output: Contribution to journalArticle

    46 Citations (Scopus)

    Abstract

    Mitochondrial thermodynamics is the key to understand cellular activities related to homeostasis and energy balance. Here, we report the first ratiometric fluorescent molecular probe (Mito-RTP) that is selectively localized in the mitochondria and visualize the temperature. We confirmed that Mito-RTP could work as a ratiometric thermometer in a cuvette and living cells.

    Original languageEnglish
    Pages (from-to)6194-6197
    Number of pages4
    JournalChemical Communications
    Volume51
    Issue number28
    DOIs
    Publication statusPublished - 2015 Apr 11

    Fingerprint

    Molecular Probes
    Mitochondria
    Thermometers
    Energy balance
    Visualization
    Cells
    Thermodynamics
    Temperature

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis
    • Ceramics and Composites
    • Electronic, Optical and Magnetic Materials
    • Surfaces, Coatings and Films
    • Materials Chemistry
    • Metals and Alloys

    Cite this

    A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells. / Homma, Mitsumasa; Takei, Yoshiaki; Murata, Atsushi; Inoue, Takafumi; Takeoka, Shinji.

    In: Chemical Communications, Vol. 51, No. 28, 11.04.2015, p. 6194-6197.

    Research output: Contribution to journalArticle

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