A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Mitsumasa Homma, Yoshiaki Takei, Atsushi Murata, Takafumi Inoue, Shinji Takeoka

    Research output: Contribution to journalArticlepeer-review

    65 Citations (Scopus)

    Abstract

    Mitochondrial thermodynamics is the key to understand cellular activities related to homeostasis and energy balance. Here, we report the first ratiometric fluorescent molecular probe (Mito-RTP) that is selectively localized in the mitochondria and visualize the temperature. We confirmed that Mito-RTP could work as a ratiometric thermometer in a cuvette and living cells.

    Original languageEnglish
    Pages (from-to)6194-6197
    Number of pages4
    JournalChemical Communications
    Volume51
    Issue number28
    DOIs
    Publication statusPublished - 2015 Apr 11

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis
    • Ceramics and Composites
    • Electronic, Optical and Magnetic Materials
    • Surfaces, Coatings and Films
    • Materials Chemistry
    • Metals and Alloys

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