TY - JOUR
T1 - A real-time assessment of the effect of exercise in chronic fatigue syndrome
AU - Yoshiuchi, Kazuhiro
AU - Cook, Dane B.
AU - Ohashi, Kyoko
AU - Kumano, Hiroaki
AU - Kuboki, Tomifusa
AU - Yamamoto, Yoshiharu
AU - Natelson, Benjamin H.
N1 - Funding Information:
This study was supported by NIH AI-32247 (BHN). This material is the result of work supported with resources and use of facilities at the VA New Jersey Health Care System (VANJHCS), East Orange, NJ.
PY - 2007/12/5
Y1 - 2007/12/5
N2 - Patients with chronic fatigue syndrome (CFS) report substantial symptom worsening after exercise. However, the time course over which this develops has not been explored. Therefore, the objective of this study was to investigate the influence of exercise on subjective symptoms and on cognitive function in CFS patients in natural settings using a computerized ecological momentary assessment method, which allowed us to track the effects of exercise within and across days. Subjects were 9 female patients with CFS and 9 healthy women. A watch-type computer was used to collect real-time data on physical and psychological symptoms and cognitive function for 1week before and 2weeks after a maximal exercise test. For each variable, we investigated temporal changes after exercise using multilevel modeling. Following exercise, physical symptoms did get worse but not until a five-day delay in CFS patients. Despite this, there was no difference in the temporal pattern of changes in psychological symptoms or in cognitive function after exercise between CFS patients and controls. In conclusion, physical symptoms worsened after several days delay in patients with CFS following exercise while psychological symptoms or cognitive function did not change after exercise.
AB - Patients with chronic fatigue syndrome (CFS) report substantial symptom worsening after exercise. However, the time course over which this develops has not been explored. Therefore, the objective of this study was to investigate the influence of exercise on subjective symptoms and on cognitive function in CFS patients in natural settings using a computerized ecological momentary assessment method, which allowed us to track the effects of exercise within and across days. Subjects were 9 female patients with CFS and 9 healthy women. A watch-type computer was used to collect real-time data on physical and psychological symptoms and cognitive function for 1week before and 2weeks after a maximal exercise test. For each variable, we investigated temporal changes after exercise using multilevel modeling. Following exercise, physical symptoms did get worse but not until a five-day delay in CFS patients. Despite this, there was no difference in the temporal pattern of changes in psychological symptoms or in cognitive function after exercise between CFS patients and controls. In conclusion, physical symptoms worsened after several days delay in patients with CFS following exercise while psychological symptoms or cognitive function did not change after exercise.
KW - Chronic fatigue syndrome
KW - Ecological momentary assessment
KW - Multilevel modeling
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U2 - 10.1016/j.physbeh.2007.07.001
DO - 10.1016/j.physbeh.2007.07.001
M3 - Article
C2 - 17655887
AN - SCOPUS:36048971662
SN - 0031-9384
VL - 92
SP - 963
EP - 968
JO - Physiology and Behavior
JF - Physiology and Behavior
IS - 5
ER -