A rotaxane-like complex with controlled-release characteristics

Sheng Hsien Chiu, Stuart J. Rowan, Stuart J. Cantrill, Peter T. Glink, Robin L. Garrell, J. Fraser Stoddart

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

(matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

Original languageEnglish
Pages (from-to)3631-3634
Number of pages4
JournalOrganic Letters
Volume2
Issue number23
Publication statusPublished - 2000 Nov 16
Externally publishedYes

Fingerprint

Rotaxanes
Crowns
Half-Life
Temperature
half life
polarity
dissociation
rings
matrices
temperature

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Chiu, S. H., Rowan, S. J., Cantrill, S. J., Glink, P. T., Garrell, R. L., & Stoddart, J. F. (2000). A rotaxane-like complex with controlled-release characteristics. Organic Letters, 2(23), 3631-3634.

A rotaxane-like complex with controlled-release characteristics. / Chiu, Sheng Hsien; Rowan, Stuart J.; Cantrill, Stuart J.; Glink, Peter T.; Garrell, Robin L.; Stoddart, J. Fraser.

In: Organic Letters, Vol. 2, No. 23, 16.11.2000, p. 3631-3634.

Research output: Contribution to journalArticle

Chiu, SH, Rowan, SJ, Cantrill, SJ, Glink, PT, Garrell, RL & Stoddart, JF 2000, 'A rotaxane-like complex with controlled-release characteristics', Organic Letters, vol. 2, no. 23, pp. 3631-3634.
Chiu SH, Rowan SJ, Cantrill SJ, Glink PT, Garrell RL, Stoddart JF. A rotaxane-like complex with controlled-release characteristics. Organic Letters. 2000 Nov 16;2(23):3631-3634.
Chiu, Sheng Hsien ; Rowan, Stuart J. ; Cantrill, Stuart J. ; Glink, Peter T. ; Garrell, Robin L. ; Stoddart, J. Fraser. / A rotaxane-like complex with controlled-release characteristics. In: Organic Letters. 2000 ; Vol. 2, No. 23. pp. 3631-3634.
@article{aa99c1c41f3b4ee69ca2e0935590db5c,
title = "A rotaxane-like complex with controlled-release characteristics",
abstract = "(matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a {"}threading-followed-by-stoppering{"} approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.",
author = "Chiu, {Sheng Hsien} and Rowan, {Stuart J.} and Cantrill, {Stuart J.} and Glink, {Peter T.} and Garrell, {Robin L.} and Stoddart, {J. Fraser}",
year = "2000",
month = "11",
day = "16",
language = "English",
volume = "2",
pages = "3631--3634",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "23",

}

TY - JOUR

T1 - A rotaxane-like complex with controlled-release characteristics

AU - Chiu, Sheng Hsien

AU - Rowan, Stuart J.

AU - Cantrill, Stuart J.

AU - Glink, Peter T.

AU - Garrell, Robin L.

AU - Stoddart, J. Fraser

PY - 2000/11/16

Y1 - 2000/11/16

N2 - (matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

AB - (matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

UR - http://www.scopus.com/inward/record.url?scp=0034676572&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034676572&partnerID=8YFLogxK

M3 - Article

VL - 2

SP - 3631

EP - 3634

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 23

ER -