A study of magnetic drug delivery system using bulk high temperature superconducting magnet

Shigehiro Nishijima, Shin Ichi Takeda, Fumihito Mishima, Yasuhiko Tabata, Masaya Yamamoto, Jun Ichiro Joh, Hiroshi Iseki, Yoshihiro Muragaki, Akira Sasaki, Jun Kubota, Norihide Saho

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A magnetic drug delivery system (MDDS) has been studied to navigate and/or accumulate the magnetic seeded drug at a local diseased part in the human body. The bulk high temperature superconductors (HTS) are employed to control the drug because they would produce the required magnetic fields for MDDS. The trajectory of the ferromagnetic particles in the blood vessel was calculated and the possibility of the navigation of the drug is discussed. In the experiment the HTS (GdBaCuO) which produces the magnetic field of 4.5 T at the surface, was located 25 mm apart from the Y-shaped blood vessel. The drug navigation probability to the desired direction was confirmed to be higher than 80%. A rat experiment was also performed successfully using a permanent magnet. The possible MDDS system will be discussed.

Original languageEnglish
Article number4517321
Pages (from-to)874-877
Number of pages4
JournalIEEE Transactions on Applied Superconductivity
Volume18
Issue number2
DOIs
Publication statusPublished - 2008 Jun
Externally publishedYes

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Keywords

  • Bulk high temperature superconductor
  • Magnetic drug delivery system
  • Magnetic seeded drug
  • Nano-sized particle
  • Navigation of drag

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Physics and Astronomy (miscellaneous)

Cite this

Nishijima, S., Takeda, S. I., Mishima, F., Tabata, Y., Yamamoto, M., Joh, J. I., Iseki, H., Muragaki, Y., Sasaki, A., Kubota, J., & Saho, N. (2008). A study of magnetic drug delivery system using bulk high temperature superconducting magnet. IEEE Transactions on Applied Superconductivity, 18(2), 874-877. [4517321]. https://doi.org/10.1109/TASC.2008.921967