@inproceedings{0fbbd546ddc443c099853c88cc7185e0,
title = "A visual analytics of geometric distances between amino acids and surface pockets of proteins",
abstract = "Protein is the major component of the organism. It has a unique three-dimensional structure determined by its amino acid sequence. A concave (pocket) on the surface of a protein is known to be the best target for a drug to react. We started analyzing how' drug ability' of proteins related to the location of amino acids in a pocket. For as tarter of the study, this paper presents a visualization tool for distance analysis between pockets and the amino acid residue. Provided that a protein surface is described by a triangular mesh, this tool first identifies pockets on the protein surface, specifies the deepest point and outer loops of the pocket, and calculates distances between atoms of an amino acid residue and the deepest point or the outer loops of the pocket. The tool then visualizes the statistics of the distance calculation results by poly line charts and the distribution by scatter plots. This paper proposes a biological interpretation of the visualization results.",
keywords = "Amino acid, Pocket identification, Protein, Visualization",
author = "Makiko Miyoshi and Ayaka Kaneko and Takayuki Itoh and Kei Yura",
year = "2014",
month = sep,
day = "18",
doi = "10.1109/IV.2014.38",
language = "English",
series = "Proceedings of the International Conference on Information Visualisation",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "164--169",
editor = "Marchese, {Francis T.} and Urska Cvek and Marjan Trutschl and Georges Grinstein and Anna Ursyn and Gilles Venturini and Wyeld, {Theodor G.} and Sarah Kenderdine and Fatma Bouali and Muhammad Sarfraz and Ebad Banissi and Bannatyne, {Mark W. McK.} and Vladimir Geroimenko and Sarah Kenderdine and Sarah Kenderdine",
booktitle = "Proceedings - 2014 18th International Conference on Information Visualisation",
note = "2014 18th International Conference on Information Visualisation: Visualisation, BioMedical Visualization, Visualisation on Built and Rural Environments and Geometric Modelling and Imaging, IV 2014 ; Conference date: 16-07-2014 Through 18-07-2014",
}