Absence of diglyceride kinase activity in the photoreceptor cells of Drosophila mutants

Tohru Yoshioka, Hiroko Inoue, Yoshiki Hotta

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Diglyceride kinase (DG) activity was found to be almost absent in the photoreceptor cells of Drosophila vision mutants, norpA (no receptor potential A). Other enzymes related to the phosphatidic acid (PA) metabolism, such as monoacyl-glycerophosphate acyltransferase and PA phosphatase, were normal in the mutant. The deficiency in PA content in the retinular cells of norpA, demonstrated by 32P incorporation in vivo is, therefore, due to abnormal reduction in DG kinase activity. The DG kinase was found to be localized in the retinular cell by assaying its activity in the mutants rdgA (receptor cells degenerated) and sine oculis (compound eyes absent).

Original languageEnglish
Pages (from-to)389-395
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume119
Issue number1
DOIs
Publication statusPublished - 1984 Feb 29
Externally publishedYes

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Diacylglycerol Kinase
Photoreceptor Cells
Drosophila
Phosphatidic Acids
Glycerol-3-Phosphate O-Acyltransferase
Phosphotransferases
Phosphatidate Phosphatase
Metabolism
Enzymes

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Absence of diglyceride kinase activity in the photoreceptor cells of Drosophila mutants. / Yoshioka, Tohru; Inoue, Hiroko; Hotta, Yoshiki.

In: Biochemical and Biophysical Research Communications, Vol. 119, No. 1, 29.02.1984, p. 389-395.

Research output: Contribution to journalArticle

Yoshioka, Tohru ; Inoue, Hiroko ; Hotta, Yoshiki. / Absence of diglyceride kinase activity in the photoreceptor cells of Drosophila mutants. In: Biochemical and Biophysical Research Communications. 1984 ; Vol. 119, No. 1. pp. 389-395.
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