Absence of phosphatidylinositol phosphodiesterase in the head of a Drosophila visual mutant, norpA (no receptor potential A)

Tohru Yoshioka, Hiroko Inoue, Yoshiki Hotta

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Abstract

Phosphatidylinositol phosphodiesterase activity was found to be entirely absent in the head of the Drosophila visual mutant, norpA. It was also demonstrated that the enzyme activity was highly concentrated in the retinular cells of a normal head. Furthermore, the enzyme was revealed to be in a membrane bound form. In view of the present results and our previous work on the reduction of diacylglycerol kinase activity in the norpA mutant, phosphatidylinositol metabolism may play an important role in the generation of photoreceptor potentials.

Original languageEnglish
Pages (from-to)1251-1254
Number of pages4
JournalJournal of Biochemistry
Volume97
Issue number4
Publication statusPublished - 1985 Apr
Externally publishedYes

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ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology
  • Biochemistry

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