Acceleration of mounting behaviors in female rats by ibotenic acid lesions in the ventromedial hypothalamic nucleus

Takahiro Matsumoto, Korehito Yamanouchi

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    To clarify the role of the ventromedial (VMH) or dorsomedial (DMH) hypothalamic nucleus in regulating male sexual behavior in female rats, radiofrequency or ibotenic acid lesions were made in ovariectomized rats, and three behavioral tests in total were carried out after implantation of Silastic tubes containing testosterone. As a result, females with radiofrequency or ibotenic acid lesions in the VMH showed higher levels of mounting behavior than those in females with no brain surgery or with sham-operation. The incidence of intromissive pattern in females with ibotenic acid lesions but not in females with radiofrequency lesions was higher than those in other female control groups. In the group of radiofrequency lesions in the DMH, both frequencies of mounting and intromissive pattern were lower than those in control and sham groups. No ejaculatory pattern was seen in any of the female groups. These results indicate that neuronal cell bodies in the VMH, but not in the DMH, exert an inhibitory influence on mounting activity in female rats. Copyright (C) 2000 Elsevier Science Ireland Ltd.

    Original languageEnglish
    Pages (from-to)143-146
    Number of pages4
    JournalNeuroscience Letters
    Volume291
    Issue number3
    DOIs
    Publication statusPublished - 2000 Sep 22

    Fingerprint

    Ventromedial Hypothalamic Nucleus
    Ibotenic Acid
    Dimenhydrinate
    Dorsomedial Hypothalamic Nucleus
    Control Groups
    Sexual Behavior
    Testosterone

    Keywords

    • Female rat
    • Ibotenic acid
    • Mounting behavior
    • Ventromedial hypothalamic nucleus

    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this

    Acceleration of mounting behaviors in female rats by ibotenic acid lesions in the ventromedial hypothalamic nucleus. / Matsumoto, Takahiro; Yamanouchi, Korehito.

    In: Neuroscience Letters, Vol. 291, No. 3, 22.09.2000, p. 143-146.

    Research output: Contribution to journalArticle

    Matsumoto, Takahiro ; Yamanouchi, Korehito. / Acceleration of mounting behaviors in female rats by ibotenic acid lesions in the ventromedial hypothalamic nucleus. In: Neuroscience Letters. 2000 ; Vol. 291, No. 3. pp. 143-146.
    @article{c6675ea1f399423c8abd37dc27c7b026,
    title = "Acceleration of mounting behaviors in female rats by ibotenic acid lesions in the ventromedial hypothalamic nucleus",
    abstract = "To clarify the role of the ventromedial (VMH) or dorsomedial (DMH) hypothalamic nucleus in regulating male sexual behavior in female rats, radiofrequency or ibotenic acid lesions were made in ovariectomized rats, and three behavioral tests in total were carried out after implantation of Silastic tubes containing testosterone. As a result, females with radiofrequency or ibotenic acid lesions in the VMH showed higher levels of mounting behavior than those in females with no brain surgery or with sham-operation. The incidence of intromissive pattern in females with ibotenic acid lesions but not in females with radiofrequency lesions was higher than those in other female control groups. In the group of radiofrequency lesions in the DMH, both frequencies of mounting and intromissive pattern were lower than those in control and sham groups. No ejaculatory pattern was seen in any of the female groups. These results indicate that neuronal cell bodies in the VMH, but not in the DMH, exert an inhibitory influence on mounting activity in female rats. Copyright (C) 2000 Elsevier Science Ireland Ltd.",
    keywords = "Female rat, Ibotenic acid, Mounting behavior, Ventromedial hypothalamic nucleus",
    author = "Takahiro Matsumoto and Korehito Yamanouchi",
    year = "2000",
    month = "9",
    day = "22",
    doi = "10.1016/S0304-3940(00)01388-4",
    language = "English",
    volume = "291",
    pages = "143--146",
    journal = "Neuroscience Letters",
    issn = "0304-3940",
    publisher = "Elsevier Ireland Ltd",
    number = "3",

    }

    TY - JOUR

    T1 - Acceleration of mounting behaviors in female rats by ibotenic acid lesions in the ventromedial hypothalamic nucleus

    AU - Matsumoto, Takahiro

    AU - Yamanouchi, Korehito

    PY - 2000/9/22

    Y1 - 2000/9/22

    N2 - To clarify the role of the ventromedial (VMH) or dorsomedial (DMH) hypothalamic nucleus in regulating male sexual behavior in female rats, radiofrequency or ibotenic acid lesions were made in ovariectomized rats, and three behavioral tests in total were carried out after implantation of Silastic tubes containing testosterone. As a result, females with radiofrequency or ibotenic acid lesions in the VMH showed higher levels of mounting behavior than those in females with no brain surgery or with sham-operation. The incidence of intromissive pattern in females with ibotenic acid lesions but not in females with radiofrequency lesions was higher than those in other female control groups. In the group of radiofrequency lesions in the DMH, both frequencies of mounting and intromissive pattern were lower than those in control and sham groups. No ejaculatory pattern was seen in any of the female groups. These results indicate that neuronal cell bodies in the VMH, but not in the DMH, exert an inhibitory influence on mounting activity in female rats. Copyright (C) 2000 Elsevier Science Ireland Ltd.

    AB - To clarify the role of the ventromedial (VMH) or dorsomedial (DMH) hypothalamic nucleus in regulating male sexual behavior in female rats, radiofrequency or ibotenic acid lesions were made in ovariectomized rats, and three behavioral tests in total were carried out after implantation of Silastic tubes containing testosterone. As a result, females with radiofrequency or ibotenic acid lesions in the VMH showed higher levels of mounting behavior than those in females with no brain surgery or with sham-operation. The incidence of intromissive pattern in females with ibotenic acid lesions but not in females with radiofrequency lesions was higher than those in other female control groups. In the group of radiofrequency lesions in the DMH, both frequencies of mounting and intromissive pattern were lower than those in control and sham groups. No ejaculatory pattern was seen in any of the female groups. These results indicate that neuronal cell bodies in the VMH, but not in the DMH, exert an inhibitory influence on mounting activity in female rats. Copyright (C) 2000 Elsevier Science Ireland Ltd.

    KW - Female rat

    KW - Ibotenic acid

    KW - Mounting behavior

    KW - Ventromedial hypothalamic nucleus

    UR - http://www.scopus.com/inward/record.url?scp=0034703596&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0034703596&partnerID=8YFLogxK

    U2 - 10.1016/S0304-3940(00)01388-4

    DO - 10.1016/S0304-3940(00)01388-4

    M3 - Article

    C2 - 10984627

    AN - SCOPUS:0034703596

    VL - 291

    SP - 143

    EP - 146

    JO - Neuroscience Letters

    JF - Neuroscience Letters

    SN - 0304-3940

    IS - 3

    ER -