Accurate polarity control and parallel alignment of actin filaments for myosin-powered transport systems

Makito Miyazaki, Kazuhiko Kinosita Jr. Jr., Katsuyuki Shiroguchi

    Research output: Contribution to journalArticle

    Abstract

    An actin filament is a micrometer-long biological filament, which serves as a track of transport systems in cells. The filament exhibits polarity while myosin transports a cargo along it unidirectionally. Here, we established a method to align many actin filaments parallel with each other on a substrate with uniform (>99%) polarity as assessed by myosin movements. This actin array is an ideal candidate for the construction of a nano-scale unidirectional transport system powered by myosin.

    Original languageEnglish
    Pages (from-to)8728-8733
    Number of pages6
    JournalRSC Advances
    Volume3
    Issue number23
    DOIs
    Publication statusPublished - 2013 Jun 21

    ASJC Scopus subject areas

    • Chemical Engineering(all)
    • Chemistry(all)

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