Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women

Masaki Takahashi, Masashi Miyashita, Katsuhiko Suzuki, Seong Ryu Bae, Hyeonki Kim, Takuya Wakisaka, Yuji Matsui, Masao Takeshita, Koichi Yasunaga

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Elevated postprandial hyperglycaemia and oxidative stress increase the risks of type 2 diabetes and CVD. Green tea catechin possesses antidiabetic properties and antioxidant capacity. In the present study, we examined the acute and continuous effects of ingestion of catechin-rich green tea on postprandial hyperglycaemia and oxidative stress in healthy postmenopausal women. Participants were randomly assigned into the placebo (P, n 11) or green tea (GT, n 11) group. The GT group consumed a catechin-rich green tea (catechins 615 mg/350 ml) beverage per d for 4 weeks. The P group consumed a placebo (catechins 92 mg/350 ml) beverage per d for 4 weeks. At baseline and after 4 weeks, participants of each group consumed their designated beverages with breakfast and consumed lunch 3 h after breakfast. Venous blood samples were collected in the fasted state (0 h) and at 2, 4 and 6 h after breakfast. Postprandial glucose concentrations were 3 % lower in the GT group than in the P group (three-factor ANOVA, group × time interaction, P< 0·05). Serum concentrations of the derivatives of reactive oxygen metabolites increased after meals (P< 0·05), but no effect of catechin-rich green tea intake was observed. Conversely, serum postprandial thioredoxin concentrations were 5 % higher in the GT group than in the P group (three-factor ANOVA, group × time interaction, P< 0·05). These findings indicate that an acute ingestion of catechin-rich green tea has beneficial effects on postprandial glucose and redox homeostasis in postmenopausal women.

Original languageEnglish
Pages (from-to)1542-1550
Number of pages9
JournalBritish Journal of Nutrition
Volume112
Issue number9
DOIs
Publication statusPublished - 2014 Nov 14

Fingerprint

Thioredoxins
Catechin
Tea
Eating
Glucose
Breakfast
Serum
Beverages
Hyperglycemia
Analysis of Variance
Oxidative Stress
Placebos
Lunch
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Oxidation-Reduction
Meals
Homeostasis
Antioxidants
Oxygen

Keywords

  • Catechins
  • Postprandial antioxidant capacity
  • Postprandial glucose
  • Postprandial oxidative stress

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women. / Takahashi, Masaki; Miyashita, Masashi; Suzuki, Katsuhiko; Bae, Seong Ryu; Kim, Hyeonki; Wakisaka, Takuya; Matsui, Yuji; Takeshita, Masao; Yasunaga, Koichi.

In: British Journal of Nutrition, Vol. 112, No. 9, 14.11.2014, p. 1542-1550.

Research output: Contribution to journalArticle

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