Alteration of local immunity in the oral cavity after endurance running

Takayuki Akimoto, Takao Akama, Koichi Sugiura, Mieko Tatsuno, Yasuko Koda, Takahiro Waku, Ichiro Kono

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

To investigate the effect of intense exercise on immunological factors in saliva, we measured secretory immunoglobulin A (sIgA), lactoferrin and fibronectin. We used a reliable saliva collection method that has already been reported. Timed saliva samples were obtained from 16 healthy young males. Samples were collected before, immediately after, 1 day after and 5 days after endurance running (42.195 km). The concentrations (μg/ml) of sIgA, lactoferrin and fibronectin were measured by ELISA, and the secretion rates (μg/min) of each were calculated. Immediately after the exercise, the concentration of total protein in saliva increased significantly, but the sIgA secretion rate decreased to 53%. The secretion rates of both lactoferrin and fibronectin did not change significantly. The local immune system plays an important role in mucosal surface defense against upper respiratory tract infection. The sIgA level in the oral cavity was temporarily decreased after intense exercise. A decreased sIgA secretion rate might partly explain the increased susceptibility to upper respiratory tract infection after endurance exercise.

Original languageEnglish
Pages (from-to)53-62
Number of pages10
JournalJapanese Journal of Physical Fitness and Sports Medicine
Volume47
Issue number1
Publication statusPublished - 1998 Feb
Externally publishedYes

Fingerprint

Secretory Immunoglobulin A
Mouth
Immunity
Saliva
Lactoferrin
Fibronectins
Respiratory Tract Infections
Immunologic Factors
Immune System
Enzyme-Linked Immunosorbent Assay
Proteins

Keywords

  • Endurance running
  • Fibronectin
  • Lactoferrin
  • Saliva
  • sIgA

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Alteration of local immunity in the oral cavity after endurance running. / Akimoto, Takayuki; Akama, Takao; Sugiura, Koichi; Tatsuno, Mieko; Koda, Yasuko; Waku, Takahiro; Kono, Ichiro.

In: Japanese Journal of Physical Fitness and Sports Medicine, Vol. 47, No. 1, 02.1998, p. 53-62.

Research output: Contribution to journalArticle

Akimoto, Takayuki ; Akama, Takao ; Sugiura, Koichi ; Tatsuno, Mieko ; Koda, Yasuko ; Waku, Takahiro ; Kono, Ichiro. / Alteration of local immunity in the oral cavity after endurance running. In: Japanese Journal of Physical Fitness and Sports Medicine. 1998 ; Vol. 47, No. 1. pp. 53-62.
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