An aptazyme-based molecular device that converts a small-molecule input into an RNA output

Shotaro Ayukawa, Yoko Sakai, Daisuke Kiga

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We describe the construction of an aptazyme-based molecular device that converts, through a cascade of reactions, a small-molecule input into output RNA strands. This device is applicable as an interface between a small molecule and a molecular system that accepts only nucleic acid input.

Original languageEnglish
Pages (from-to)7556-7558
Number of pages3
JournalChemical Communications
Volume48
Issue number61
DOIs
Publication statusPublished - 2012 Aug 7
Externally publishedYes

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RNA
Molecules
Nucleic acids
Nucleic Acids

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

An aptazyme-based molecular device that converts a small-molecule input into an RNA output. / Ayukawa, Shotaro; Sakai, Yoko; Kiga, Daisuke.

In: Chemical Communications, Vol. 48, No. 61, 07.08.2012, p. 7556-7558.

Research output: Contribution to journalArticle

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