An enantioselective approach to (-)-platencin via catalytic asymmetric intramolecular cyclopropanation

Sho Hirai, Masahisa Nakada

    Research output: Contribution to journalArticle

    39 Citations (Scopus)

    Abstract

    This Letter describes an enantioselective approach to (-)-platencin. A uniquely functionalized chiral intermediate, which was prepared via the highly enantioselective catalytic asymmetric intramolecular cyclopropanation (CAIMCP) that we have developed, was successfully transformed to Nicolaou's intermediate in his total synthesis of (-)-platencin.

    Original languageEnglish
    Pages (from-to)5076-5079
    Number of pages4
    JournalTetrahedron Letters
    Volume51
    Issue number38
    DOIs
    Publication statusPublished - 2010

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    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    An enantioselective approach to (-)-platencin via catalytic asymmetric intramolecular cyclopropanation. / Hirai, Sho; Nakada, Masahisa.

    In: Tetrahedron Letters, Vol. 51, No. 38, 2010, p. 5076-5079.

    Research output: Contribution to journalArticle

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