Multi-view video can provide users a 3-D and virtual reality perception by its multiple viewing angles. In recent years, the depth image-based rendering (DIBR) is generally used to synthesize virtual view images in free viewpoint television (FTV) and three-dimensional (3-D) video. In order to conceal the zero-region more accurately and improve the quality of virtual view synthesized frame, an integrated Hole-filling Algorithm for View Synthesis is proposed in this paper. It contains five parts: the different regions distinguishing algorithm, foreground and background boundary detection, the texture image isophotes detection, the textural and structural isophotes prediction algorithm, the in-painting algorithm with gradient priority order. Based on the texture isophotes prediction with geometrical principle and the in-painting algorithm with gradient priority order, the boundary information of the foreground is much clearer and the texture information in the zero-region can be concealed much more accurately than the previous work. The vision quality mainly depends on the distortion of the structural information. Through the experimental results, the proposed algorithm not only improves the objective quality of the virtual image, but also improves the subjective quality of the virtual image a lot, and the human vision quality is also improved obviously based on the subjective results. Especially, it ensures the boundary contours of the foreground objects and the textural and the structural information.