An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors

Hisashi Sugime, Takuya Ushiyama, Keita Nishimura, Yutaka Ohno, Suguru Noda

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A highly sensitive interdigitated electrode (IDE) with vertically aligned dense carbon nanotube forests directly grown on conductive supports was demonstrated by combining UV lithography and a low temperature chemical vapor deposition process (470 °C). The cyclic voltammetry (CV) measurements of K4[Fe(CN)6] showed that the redox current of the IDE with CNT forests (CNTF-IDE) reached the steady state much more quickly compared to that of conventional gold IDE (Au-IDE). The performance of the CNTF-IDE largely depended on the geometry of the electrodes (e.g. width and gap). With the optimum three-dimensional electrode structure, the anodic current was amplified by a factor of ∼18 and ∼67 in the CV and the chronoamperometry measurements, respectively. The collection efficiency, defined as the ratio of the cathodic current to the anodic current at steady state, was improved up to 97.3%. The selective detection of dopamine (DA) under the coexistence of l-ascorbic acid with high concentration (100 μM) was achieved with a linear range of 100 nM-100 μM, a sensitivity of 14.3 mA mol-1 L, and a limit of detection (LOD, S/N = 3) of 42 nM. Compared to the conventional carbon electrodes, the CNTF-IDE showed superior anti-fouling property, which is of significant importance for practical applications, with a negligible shift of the half-wave potential (ΔE1/2 < 1.4 mV) for repeated CV measurements of DA at high concentration (100 μM).

Original languageEnglish
Pages (from-to)3635-3642
Number of pages8
JournalAnalyst
Volume143
Issue number15
DOIs
Publication statusPublished - 2018 Aug 7

Fingerprint

Carbon Nanotubes
Biosensing Techniques
Biosensors
Carbon nanotubes
Electrodes
electrode
Ciliary Neurotrophic Factor
Cyclic voltammetry
Dopamine
Forests
carbon nanotube
Chronoamperometry
antifouling
Ascorbic acid
ascorbic acid
Fouling
Gold
Lithography
Ascorbic Acid
coexistence

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

Cite this

An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors. / Sugime, Hisashi; Ushiyama, Takuya; Nishimura, Keita; Ohno, Yutaka; Noda, Suguru.

In: Analyst, Vol. 143, No. 15, 07.08.2018, p. 3635-3642.

Research output: Contribution to journalArticle

Sugime, Hisashi ; Ushiyama, Takuya ; Nishimura, Keita ; Ohno, Yutaka ; Noda, Suguru. / An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors. In: Analyst. 2018 ; Vol. 143, No. 15. pp. 3635-3642.
@article{ad04147dcf234358b370071e8d5cdc4e,
title = "An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors",
abstract = "A highly sensitive interdigitated electrode (IDE) with vertically aligned dense carbon nanotube forests directly grown on conductive supports was demonstrated by combining UV lithography and a low temperature chemical vapor deposition process (470 °C). The cyclic voltammetry (CV) measurements of K4[Fe(CN)6] showed that the redox current of the IDE with CNT forests (CNTF-IDE) reached the steady state much more quickly compared to that of conventional gold IDE (Au-IDE). The performance of the CNTF-IDE largely depended on the geometry of the electrodes (e.g. width and gap). With the optimum three-dimensional electrode structure, the anodic current was amplified by a factor of ∼18 and ∼67 in the CV and the chronoamperometry measurements, respectively. The collection efficiency, defined as the ratio of the cathodic current to the anodic current at steady state, was improved up to 97.3{\%}. The selective detection of dopamine (DA) under the coexistence of l-ascorbic acid with high concentration (100 μM) was achieved with a linear range of 100 nM-100 μM, a sensitivity of 14.3 mA mol-1 L, and a limit of detection (LOD, S/N = 3) of 42 nM. Compared to the conventional carbon electrodes, the CNTF-IDE showed superior anti-fouling property, which is of significant importance for practical applications, with a negligible shift of the half-wave potential (ΔE1/2 < 1.4 mV) for repeated CV measurements of DA at high concentration (100 μM).",
author = "Hisashi Sugime and Takuya Ushiyama and Keita Nishimura and Yutaka Ohno and Suguru Noda",
year = "2018",
month = "8",
day = "7",
doi = "10.1039/c8an00528a",
language = "English",
volume = "143",
pages = "3635--3642",
journal = "The Analyst",
issn = "0003-2654",
publisher = "Royal Society of Chemistry",
number = "15",

}

TY - JOUR

T1 - An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors

AU - Sugime, Hisashi

AU - Ushiyama, Takuya

AU - Nishimura, Keita

AU - Ohno, Yutaka

AU - Noda, Suguru

PY - 2018/8/7

Y1 - 2018/8/7

N2 - A highly sensitive interdigitated electrode (IDE) with vertically aligned dense carbon nanotube forests directly grown on conductive supports was demonstrated by combining UV lithography and a low temperature chemical vapor deposition process (470 °C). The cyclic voltammetry (CV) measurements of K4[Fe(CN)6] showed that the redox current of the IDE with CNT forests (CNTF-IDE) reached the steady state much more quickly compared to that of conventional gold IDE (Au-IDE). The performance of the CNTF-IDE largely depended on the geometry of the electrodes (e.g. width and gap). With the optimum three-dimensional electrode structure, the anodic current was amplified by a factor of ∼18 and ∼67 in the CV and the chronoamperometry measurements, respectively. The collection efficiency, defined as the ratio of the cathodic current to the anodic current at steady state, was improved up to 97.3%. The selective detection of dopamine (DA) under the coexistence of l-ascorbic acid with high concentration (100 μM) was achieved with a linear range of 100 nM-100 μM, a sensitivity of 14.3 mA mol-1 L, and a limit of detection (LOD, S/N = 3) of 42 nM. Compared to the conventional carbon electrodes, the CNTF-IDE showed superior anti-fouling property, which is of significant importance for practical applications, with a negligible shift of the half-wave potential (ΔE1/2 < 1.4 mV) for repeated CV measurements of DA at high concentration (100 μM).

AB - A highly sensitive interdigitated electrode (IDE) with vertically aligned dense carbon nanotube forests directly grown on conductive supports was demonstrated by combining UV lithography and a low temperature chemical vapor deposition process (470 °C). The cyclic voltammetry (CV) measurements of K4[Fe(CN)6] showed that the redox current of the IDE with CNT forests (CNTF-IDE) reached the steady state much more quickly compared to that of conventional gold IDE (Au-IDE). The performance of the CNTF-IDE largely depended on the geometry of the electrodes (e.g. width and gap). With the optimum three-dimensional electrode structure, the anodic current was amplified by a factor of ∼18 and ∼67 in the CV and the chronoamperometry measurements, respectively. The collection efficiency, defined as the ratio of the cathodic current to the anodic current at steady state, was improved up to 97.3%. The selective detection of dopamine (DA) under the coexistence of l-ascorbic acid with high concentration (100 μM) was achieved with a linear range of 100 nM-100 μM, a sensitivity of 14.3 mA mol-1 L, and a limit of detection (LOD, S/N = 3) of 42 nM. Compared to the conventional carbon electrodes, the CNTF-IDE showed superior anti-fouling property, which is of significant importance for practical applications, with a negligible shift of the half-wave potential (ΔE1/2 < 1.4 mV) for repeated CV measurements of DA at high concentration (100 μM).

UR - http://www.scopus.com/inward/record.url?scp=85050777609&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85050777609&partnerID=8YFLogxK

U2 - 10.1039/c8an00528a

DO - 10.1039/c8an00528a

M3 - Article

AN - SCOPUS:85050777609

VL - 143

SP - 3635

EP - 3642

JO - The Analyst

JF - The Analyst

SN - 0003-2654

IS - 15

ER -