An overview of physical exercise and antioxidant supplementation influences on skeletal muscle oxidative stress

Shima Taherkhani, Kosar Valaei, Hamid Arazi*, Katsuhiko Suzuki

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

One of the essential injuries caused by moderate to high-intensity and short-duration physical activities is the overproduction of reactive oxygen species (ROS), damaging various body tissues such as skeletal muscle (SM). However, ROS is easily controlled by antioxidant defense systems during low to moderate intensity and long-term exercises. In stressful situations, antioxidant supplements are recommended to prevent ROS damage. We examined the response of SM to ROS generation during exercise using an antioxidant supplement treatment strategy in this study. The findings of this review research are paradoxical due to variances in antioxidant supplements dose and duration, intensity, length, frequency, types of exercise activities, and, in general, the lack of a regular exercise and nutrition strategy. As such, further research in this area is still being felt.

Original languageEnglish
Article number1528
JournalAntioxidants
Volume10
Issue number10
DOIs
Publication statusPublished - 2021 Oct

Keywords

  • Antioxi-dant supplementation
  • Oxidative stress
  • Physical activity
  • Reactive oxygen species
  • Skeletal muscle

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology
  • Clinical Biochemistry
  • Cell Biology

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