Analysis of Functional Groups of Porphyrins by Collision-Induced Dissociation Mass Spectrometry/Mass Spectrometry

Toshimichi Shibue, Hisashi Kambe, Hiroyuki Nishide, Yoko Ohashi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Collision-induced dissociation mass spectrometry/mass spectrometry (CID-MS/MS) was effective for estimating the substituent groups of porphyrin. The substituents of the porphyrin plane, which form the pathway for an oxygen-binding reaction, are essential for its oxygen-binding affinity. The CID-MS/MS of 5, 1 0,1 5-tris(ο-pivalamidophenyl)monoaminoporphyrinatocobalt and 5, 10, 15, 20-tetrakis(o-pivalamidophenyl)porphyrinatocopper was measured, and their fragmentations were studied using Bj E-constant and B(l—E)1/2E-constant linked-scan techniques. These CID-MS/MS spectra clearly show that the substituent group represents the eliminations of the alkyl and acyl radicals from the molecular ions. Thus, the CID-MS/MS technique has been proven to be useful for characterizing porphyrin substituents.

Original languageEnglish
Pages (from-to)793-796
Number of pages4
JournalAnalytical Sciences
Volume11
Issue number5
DOIs
Publication statusPublished - 1995

Keywords

  • B(l—E)/E-constant linked-scan
  • B/E-constant linked-scan
  • collision-induced dissociation mass spectrometry/mass spectrometry
  • mass spectrometry
  • Porphyrin

ASJC Scopus subject areas

  • Analytical Chemistry

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