Anammox organism KSU-1 expresses a NirK-type copper-containing nitrite reductase instead of a NirS-type with cytochrome cd 1

Daisuke Hira, Hidehiro Toh, Catharina T. Migita, Hiroki Okubo, Takashi Nishiyama, Masahira Hattori, Kenji Furukawa, Takao Fujii

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Abstract

Anaerobic ammonium oxidation (anammox) and denitrification are two distinct microbial reactions relevant to the global nitrogen cycle. The proposed initial step of the anammox reactions, reduction of nitrite to nitric oxide, has been postulated to be identical to that in denitrification catalyzed by the dissimilatory nitrite reductase of the cytochrome cd 1-type. Here, we characterized the copper-containing nitrite reductase homolog encoded by nirK detected in the genome of an anammox bacterium strain KSU-1. We hypothesize that this NirK-type nitrite reductase, rather than a nitrite reductase of the cytochrome cd 1-type (NirS), is likely to catalyze nitrite reduction in anammox organism KSU-1.

Original languageEnglish
Pages (from-to)1658-1663
Number of pages6
JournalFEBS Letters
Volume586
Issue number11
DOIs
Publication statusPublished - 2012 Jun 4
Externally publishedYes

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Keywords

  • Anammox
  • Copper-containing nitrite reductase
  • Denitrification
  • Dissimilatory nitrite reductase

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Cell Biology
  • Genetics
  • Molecular Biology
  • Structural Biology

Cite this

Hira, D., Toh, H., Migita, C. T., Okubo, H., Nishiyama, T., Hattori, M., Furukawa, K., & Fujii, T. (2012). Anammox organism KSU-1 expresses a NirK-type copper-containing nitrite reductase instead of a NirS-type with cytochrome cd 1 FEBS Letters, 586(11), 1658-1663. https://doi.org/10.1016/j.febslet.2012.04.041