Anti-hyperglycemic effects of sugar maple Acer saccharum and its constituent acertannin

Atsushi Honma, Tomoyuki Koyama, Kazunaga Yazawa

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

The anti-hyperglycemic effects of the leaves of sugar maple, Acer saccharum and purification and identification of the active compound were investigated. Extracts of the leaves showed a potent inhibitory effect on α-glucosidase in both in vivo and in vitro experiments. In vitro enzyme-inhibitory assay-guided fractionation of the crude extract gave active compound, acertannin (2,6-di-O-galloyl-1,5-anhydro-d-glucitol) by spectroscopic analysis. This is the first report that acertannin from A. saccharum may be used in diabetes care.

Original languageEnglish
Pages (from-to)390-394
Number of pages5
JournalFood Chemistry
Volume123
Issue number2
DOIs
Publication statusPublished - 2010 Nov 15
Externally publishedYes

Keywords

  • α-Glucosidase inhibitory effect
  • 2,6-di-O-galloyl-1,5-anhydro-d-glucitol
  • Acer saccharum
  • Acertannin
  • Diabetes mellitus

ASJC Scopus subject areas

  • Food Science
  • Analytical Chemistry

Fingerprint Dive into the research topics of 'Anti-hyperglycemic effects of sugar maple Acer saccharum and its constituent acertannin'. Together they form a unique fingerprint.

Cite this