Abstract
Over 200 strains of marine purple photosynthetic bacteria were isolated. Two strains showed antibiotic activity towards Saccharomyces cerevisiae and were tentatively identified as Chromatium purpuratum. Crude antibiotic, prepared by solvent extraction, showed a broad antimicrobial spectrum. The highest activity was found in the chromatophore fraction. Chromatographic separation of purified light harvesting complex from one strain, NKPB 031704, showed the presence of two separate pigmented compounds which were responsible for antimicrobial activity. Our findings reveal the unexpected ability of photosynthetic bacteria to produce broad spectrum antibiotics. In addition, this is the first example of intracellular localization of antibiotic activity in a marine bacterium.
| Original language | English |
|---|---|
| Pages (from-to) | 301-305 |
| Number of pages | 5 |
| Journal | FEMS Microbiology Letters |
| Volume | 84 |
| Issue number | 3 |
| Publication status | Published - 1991 Dec 1 |
| Externally published | Yes |
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Keywords
- Antibiotic
- Chromatium
- Chromatophore
- Marine bacteria
- Photosynthetic bacteria
- Purple sulfur photosynthetic bacteria
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
- Genetics
Cite this
Antibiotic production by the marine photosynthetic bacterium Chromatium purpuratum NKPB 031704 : localization of activity to the chromatophores. / Burgess, J. Grant; Miyashita, Hideaki; Sudo, Hiroaki; Matsunaga, Tadashi.
In: FEMS Microbiology Letters, Vol. 84, No. 3, 01.12.1991, p. 301-305.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antibiotic production by the marine photosynthetic bacterium Chromatium purpuratum NKPB 031704
T2 - localization of activity to the chromatophores
AU - Burgess, J. Grant
AU - Miyashita, Hideaki
AU - Sudo, Hiroaki
AU - Matsunaga, Tadashi
PY - 1991/12/1
Y1 - 1991/12/1
N2 - Over 200 strains of marine purple photosynthetic bacteria were isolated. Two strains showed antibiotic activity towards Saccharomyces cerevisiae and were tentatively identified as Chromatium purpuratum. Crude antibiotic, prepared by solvent extraction, showed a broad antimicrobial spectrum. The highest activity was found in the chromatophore fraction. Chromatographic separation of purified light harvesting complex from one strain, NKPB 031704, showed the presence of two separate pigmented compounds which were responsible for antimicrobial activity. Our findings reveal the unexpected ability of photosynthetic bacteria to produce broad spectrum antibiotics. In addition, this is the first example of intracellular localization of antibiotic activity in a marine bacterium.
AB - Over 200 strains of marine purple photosynthetic bacteria were isolated. Two strains showed antibiotic activity towards Saccharomyces cerevisiae and were tentatively identified as Chromatium purpuratum. Crude antibiotic, prepared by solvent extraction, showed a broad antimicrobial spectrum. The highest activity was found in the chromatophore fraction. Chromatographic separation of purified light harvesting complex from one strain, NKPB 031704, showed the presence of two separate pigmented compounds which were responsible for antimicrobial activity. Our findings reveal the unexpected ability of photosynthetic bacteria to produce broad spectrum antibiotics. In addition, this is the first example of intracellular localization of antibiotic activity in a marine bacterium.
KW - Antibiotic
KW - Chromatium
KW - Chromatophore
KW - Marine bacteria
KW - Photosynthetic bacteria
KW - Purple sulfur photosynthetic bacteria
UR - http://www.scopus.com/inward/record.url?scp=0025998819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025998819&partnerID=8YFLogxK
M3 - Article
C2 - 1804763
AN - SCOPUS:0025998819
VL - 84
SP - 301
EP - 305
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
SN - 0378-1097
IS - 3
ER -