Aplysinoplides A-C, cytotoxic sesterterpenes from the marine sponge Aplysinopsis digitata

Reiko Ueoka, Yoichi Nakao, Shinobu Fujii, Rob W.M. Van Soest, Shigeki Matsunaga

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20 Citations (Scopus)


Three sesterterpenoids, aplysinoplides A-C (1-3), were isolated from the marine sponge Aplysinopsis digitata. Their structures were determined on the basis of spectroscopic data. They exhibited cytotoxic activity against P388 mouse leukemia cells.

Original languageEnglish
Pages (from-to)1089-1091
Number of pages3
JournalJournal of Natural Products
Issue number6
Publication statusPublished - 2008 Jun 1


ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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