Application of visual evoked potentials for preoperative estimation of visual function in eyes with dense cataract

Hiroshi Mori*, Keiko Momose, Nobuyuki Nemoto, Fumio Okuyama, Yuichi Kimura, Motohiro Kiyosawa, Manabu Mochizuki

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Purpose: To determine whether the temporal frequency characteristics of the visual system as determined by visually evoked potentials (VEP) can be used for a preoperative estimation of the visual function in eyes with cataracts. Methods: Light stimuli driven by a pseudorandom binary sequence (PRBS) of 40950 ms duration were presented and EEG recordings were made from 13 control and 20 patients with cataracts preoperatively and 1 week after cataract operation. The first kernel of the PRBS-VEP was obtained as the first-order cross-correlation function between PRBS and PRBS-VEP. The Fourier transform of this function was used as the temporal frequency characteristic (TFC). Results: The mean ± standard deviation of the latency and amplitude of the VEP in normal controls were 110.8±4.3 ms and 2.01±0.67 μV, respectively. A high correlation (r>0.7) between the pre- and postoperative VEP waveform was obtained in 13 eyes (65%), and 14 eyes (70%) in the VEP-TFC curves. The sensitivity of the examination was 73%, 27%, and 91% for the latency, amplitude and TFC of the VEP, respectively. The specificity of the examination was 67%, 100%, and 89% for the same measures. Eleven of 12 eyes with abnormal TFC preoperatively showed retinal or optic nerve lesions postoperatively. False-negative results were seen in cases with delayed corneal edema. Conclusion: Postoperative visual function of patients with cataracts can be predicted by preoperative measurement of the TFC obtained by PRBS-VEP.

Original languageEnglish
Pages (from-to)915-922
Number of pages8
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume239
Issue number12
DOIs
Publication statusPublished - 2001 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint

Dive into the research topics of 'Application of visual evoked potentials for preoperative estimation of visual function in eyes with dense cataract'. Together they form a unique fingerprint.

Cite this