Abstract
A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.
| Original language | English |
|---|---|
| Pages (from-to) | 4186-4188 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue number | 26 |
| DOIs | |
| Publication status | Published - 2008 Jun 23 |
| Externally published | Yes |
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Keywords
- Cathepsin B
- Inhibitor
- Lumazine
- Sponge
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex. / Murayama, Shuhei; Nakao, Youichi; Matsunaga, Shigeki.
In: Tetrahedron Letters, Vol. 49, No. 26, 23.06.2008, p. 4186-4188.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex
AU - Murayama, Shuhei
AU - Nakao, Youichi
AU - Matsunaga, Shigeki
PY - 2008/6/23
Y1 - 2008/6/23
N2 - A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.
AB - A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.
KW - Cathepsin B
KW - Inhibitor
KW - Lumazine
KW - Sponge
UR - http://www.scopus.com/inward/record.url?scp=43849092308&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43849092308&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2008.04.043
DO - 10.1016/j.tetlet.2008.04.043
M3 - Article
VL - 49
SP - 4186
EP - 4188
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 26
ER -