Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex

Shuhei Murayama, Youichi Nakao, Shigeki Matsunaga

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.

Original languageEnglish
Pages (from-to)4186-4188
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number26
DOIs
Publication statusPublished - 2008 Jun 23
Externally publishedYes

Fingerprint

Pteridines
Cathepsin B
Porifera
Derivatives

Keywords

  • Cathepsin B
  • Inhibitor
  • Lumazine
  • Sponge

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex. / Murayama, Shuhei; Nakao, Youichi; Matsunaga, Shigeki.

In: Tetrahedron Letters, Vol. 49, No. 26, 23.06.2008, p. 4186-4188.

Research output: Contribution to journalArticle

Murayama, Shuhei ; Nakao, Youichi ; Matsunaga, Shigeki. / Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex. In: Tetrahedron Letters. 2008 ; Vol. 49, No. 26. pp. 4186-4188.
@article{4a11998ce8004ffdba1f61f57785470c,
title = "Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex",
abstract = "A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.",
keywords = "Cathepsin B, Inhibitor, Lumazine, Sponge",
author = "Shuhei Murayama and Youichi Nakao and Shigeki Matsunaga",
year = "2008",
month = "6",
day = "23",
doi = "10.1016/j.tetlet.2008.04.043",
language = "English",
volume = "49",
pages = "4186--4188",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "26",

}

TY - JOUR

T1 - Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex

AU - Murayama, Shuhei

AU - Nakao, Youichi

AU - Matsunaga, Shigeki

PY - 2008/6/23

Y1 - 2008/6/23

N2 - A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.

AB - A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.

KW - Cathepsin B

KW - Inhibitor

KW - Lumazine

KW - Sponge

UR - http://www.scopus.com/inward/record.url?scp=43849092308&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43849092308&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2008.04.043

DO - 10.1016/j.tetlet.2008.04.043

M3 - Article

VL - 49

SP - 4186

EP - 4188

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 26

ER -