Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex

Shuhei Murayama; Yoichi Nakao; Shigeki Matsunaga

doi:10.1016/j.tetlet.2008.04.043

Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex

Shuhei Murayama, Yoichi Nakao, Shigeki Matsunaga

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.

Original language	English
Pages (from-to)	4186-4188
Number of pages	3
Journal	Tetrahedron Letters
Volume	49
Issue number	26
DOIs	https://doi.org/10.1016/j.tetlet.2008.04.043
Publication status	Published - 2008 Jun 23
Externally published	Yes

Keywords

Cathepsin B
Inhibitor
Lumazine
Sponge

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2008.04.043

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title = "Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex",

abstract = "A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.",

keywords = "Cathepsin B, Inhibitor, Lumazine, Sponge",

author = "Shuhei Murayama and Yoichi Nakao and Shigeki Matsunaga",

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AU - Murayama, Shuhei

AU - Nakao, Yoichi

AU - Matsunaga, Shigeki

PY - 2008/6/23

Y1 - 2008/6/23

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KW - Inhibitor

KW - Lumazine

KW - Sponge

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JO - Tetrahedron Letters

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