Background factors influencing postgastrectomy syndromes after various types of gastrectomy

Shinichi Kinami, Masazumi Takahashi, Takashi Urushihara, Masami Ikeda, Masashi Yoshida, Yoshikazu Uenosono, Atsushi Oshio, Yoshimi Suzukamo, Masanori Terashima, Yasuhiro Kodera, Koji Nakada

Research output: Contribution to journalArticle

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Abstract

BACKGROUND Postgastrectomy syndromes (PGS) after curative gastrectomy for gastric cancer are influenced by not only gastrectomy type but also by background factors. Recently, a nationwide PGS study was performed using the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire. AIM To determine the influence of each background factor on PGS for each gastrectomy type using PGS assessment study (PGSAS) data as an additional analysis. METHODS The data of 2368 patients were obtained from the PGSAS. This included patients undergoing distal gastrectomy (DG) with Billroth I reconstruction, DG with Roux-en-Y reconstruction, total gastrectomy with Roux-en-Y, proximal gastrectomy, pylorus-preserving gastrectomy (PPG), and local resection. Multiple regression analysis was performed to explore the independent effects of each background factor on the main outcome measures (MOMs) of PGSAS-45 for each gastrectomy type. The background factors included postoperative period, age, sex, surgical approach (laparoscopic or open), and the status of the celiac branch of the vagal nerve. RESULTS The MOMs of DG and PPG were highly affected by background factors, whereas those of total gastrectomy with Roux-en-Y, proximal gastrectomy, and local resection were not. Worse PGS were found in females, whereas a longer postoperative period alleviated some of the MOMs. For DG and PPG, a laparoscopic approach and preservation of the celiac branch improved several MOMs. CONCLUSION Various background factors affected PGS, and their influence varied with the type of gastrectomy performed. Laparoscopic surgery and celiac branch preservation can improve PGS in patients undergoing DG and PPG.

Original languageEnglish
Pages (from-to)1111-1120
Number of pages10
JournalWorld Journal of Clinical Cases
Volume6
Issue number16
DOIs
Publication statusPublished - 2018 Dec 1

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Postgastrectomy Syndromes
Gastrectomy
Pylorus
Outcome Assessment (Health Care)
Abdomen
Postoperative Period

Keywords

  • Gastrectomy
  • Gastric cancer
  • Postgastrectomy syndrome
  • Postgastrectomy Syndrome Assessment Scale-45

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kinami, S., Takahashi, M., Urushihara, T., Ikeda, M., Yoshida, M., Uenosono, Y., ... Nakada, K. (2018). Background factors influencing postgastrectomy syndromes after various types of gastrectomy. World Journal of Clinical Cases, 6(16), 1111-1120. https://doi.org/10.12998/wjcc.v6.i16.1111

Background factors influencing postgastrectomy syndromes after various types of gastrectomy. / Kinami, Shinichi; Takahashi, Masazumi; Urushihara, Takashi; Ikeda, Masami; Yoshida, Masashi; Uenosono, Yoshikazu; Oshio, Atsushi; Suzukamo, Yoshimi; Terashima, Masanori; Kodera, Yasuhiro; Nakada, Koji.

In: World Journal of Clinical Cases, Vol. 6, No. 16, 01.12.2018, p. 1111-1120.

Research output: Contribution to journalArticle

Kinami, S, Takahashi, M, Urushihara, T, Ikeda, M, Yoshida, M, Uenosono, Y, Oshio, A, Suzukamo, Y, Terashima, M, Kodera, Y & Nakada, K 2018, 'Background factors influencing postgastrectomy syndromes after various types of gastrectomy' World Journal of Clinical Cases, vol. 6, no. 16, pp. 1111-1120. https://doi.org/10.12998/wjcc.v6.i16.1111
Kinami, Shinichi ; Takahashi, Masazumi ; Urushihara, Takashi ; Ikeda, Masami ; Yoshida, Masashi ; Uenosono, Yoshikazu ; Oshio, Atsushi ; Suzukamo, Yoshimi ; Terashima, Masanori ; Kodera, Yasuhiro ; Nakada, Koji. / Background factors influencing postgastrectomy syndromes after various types of gastrectomy. In: World Journal of Clinical Cases. 2018 ; Vol. 6, No. 16. pp. 1111-1120.
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abstract = "BACKGROUND Postgastrectomy syndromes (PGS) after curative gastrectomy for gastric cancer are influenced by not only gastrectomy type but also by background factors. Recently, a nationwide PGS study was performed using the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire. AIM To determine the influence of each background factor on PGS for each gastrectomy type using PGS assessment study (PGSAS) data as an additional analysis. METHODS The data of 2368 patients were obtained from the PGSAS. This included patients undergoing distal gastrectomy (DG) with Billroth I reconstruction, DG with Roux-en-Y reconstruction, total gastrectomy with Roux-en-Y, proximal gastrectomy, pylorus-preserving gastrectomy (PPG), and local resection. Multiple regression analysis was performed to explore the independent effects of each background factor on the main outcome measures (MOMs) of PGSAS-45 for each gastrectomy type. The background factors included postoperative period, age, sex, surgical approach (laparoscopic or open), and the status of the celiac branch of the vagal nerve. RESULTS The MOMs of DG and PPG were highly affected by background factors, whereas those of total gastrectomy with Roux-en-Y, proximal gastrectomy, and local resection were not. Worse PGS were found in females, whereas a longer postoperative period alleviated some of the MOMs. For DG and PPG, a laparoscopic approach and preservation of the celiac branch improved several MOMs. CONCLUSION Various background factors affected PGS, and their influence varied with the type of gastrectomy performed. Laparoscopic surgery and celiac branch preservation can improve PGS in patients undergoing DG and PPG.",
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AU - Takahashi, Masazumi

AU - Urushihara, Takashi

AU - Ikeda, Masami

AU - Yoshida, Masashi

AU - Uenosono, Yoshikazu

AU - Oshio, Atsushi

AU - Suzukamo, Yoshimi

AU - Terashima, Masanori

AU - Kodera, Yasuhiro

AU - Nakada, Koji

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N2 - BACKGROUND Postgastrectomy syndromes (PGS) after curative gastrectomy for gastric cancer are influenced by not only gastrectomy type but also by background factors. Recently, a nationwide PGS study was performed using the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire. AIM To determine the influence of each background factor on PGS for each gastrectomy type using PGS assessment study (PGSAS) data as an additional analysis. METHODS The data of 2368 patients were obtained from the PGSAS. This included patients undergoing distal gastrectomy (DG) with Billroth I reconstruction, DG with Roux-en-Y reconstruction, total gastrectomy with Roux-en-Y, proximal gastrectomy, pylorus-preserving gastrectomy (PPG), and local resection. Multiple regression analysis was performed to explore the independent effects of each background factor on the main outcome measures (MOMs) of PGSAS-45 for each gastrectomy type. The background factors included postoperative period, age, sex, surgical approach (laparoscopic or open), and the status of the celiac branch of the vagal nerve. RESULTS The MOMs of DG and PPG were highly affected by background factors, whereas those of total gastrectomy with Roux-en-Y, proximal gastrectomy, and local resection were not. Worse PGS were found in females, whereas a longer postoperative period alleviated some of the MOMs. For DG and PPG, a laparoscopic approach and preservation of the celiac branch improved several MOMs. CONCLUSION Various background factors affected PGS, and their influence varied with the type of gastrectomy performed. Laparoscopic surgery and celiac branch preservation can improve PGS in patients undergoing DG and PPG.

AB - BACKGROUND Postgastrectomy syndromes (PGS) after curative gastrectomy for gastric cancer are influenced by not only gastrectomy type but also by background factors. Recently, a nationwide PGS study was performed using the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire. AIM To determine the influence of each background factor on PGS for each gastrectomy type using PGS assessment study (PGSAS) data as an additional analysis. METHODS The data of 2368 patients were obtained from the PGSAS. This included patients undergoing distal gastrectomy (DG) with Billroth I reconstruction, DG with Roux-en-Y reconstruction, total gastrectomy with Roux-en-Y, proximal gastrectomy, pylorus-preserving gastrectomy (PPG), and local resection. Multiple regression analysis was performed to explore the independent effects of each background factor on the main outcome measures (MOMs) of PGSAS-45 for each gastrectomy type. The background factors included postoperative period, age, sex, surgical approach (laparoscopic or open), and the status of the celiac branch of the vagal nerve. RESULTS The MOMs of DG and PPG were highly affected by background factors, whereas those of total gastrectomy with Roux-en-Y, proximal gastrectomy, and local resection were not. Worse PGS were found in females, whereas a longer postoperative period alleviated some of the MOMs. For DG and PPG, a laparoscopic approach and preservation of the celiac branch improved several MOMs. CONCLUSION Various background factors affected PGS, and their influence varied with the type of gastrectomy performed. Laparoscopic surgery and celiac branch preservation can improve PGS in patients undergoing DG and PPG.

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