Basic Fibroblast Growth Factor-Like Substance in Nuclei of Male Germ Cells Undergoing Meiosis

Katsushi Suzuki, Takayuki Kamei, Yoji Hakamata, Keiichiro Kikukawa, Kunio Shiota, Michio Takahashi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The presence of a basic fibroblast growth factor-like immunoreactive substance was demonstrated in the nuclei of germ cells at stages from spermatocyte to spermatid in adult rat testis by using immunohistochemistry with an antibody raised against a synthetic peptide corresponding to residues 1-10 of bovine basic fibroblast growth factor [1-146]. The fluorescence was very weak in the nuclei and cytoplasm of spermatogonia, Sertoli cells, and most of the interstitial compartments, except for capillary endothelial cells. This is the first study to demonstrate the presence of basic fibroblast growth factor-like immunoreactive material in the nuclei of haploid cells in vivo.

Original languageEnglish
Pages (from-to)728-731
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume198
Issue number2
DOIs
Publication statusPublished - 1991
Externally publishedYes

Fingerprint

Meiosis
Fibroblast Growth Factor 2
Germ Cells
Cells
Fibroblast Growth Factor 1
Spermatogonia
Spermatocytes
Spermatids
Sertoli Cells
Haploidy
Endothelial cells
Testis
Rats
Cytoplasm
Endothelial Cells
Fluorescence
Immunohistochemistry
Peptides
Antibodies

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Basic Fibroblast Growth Factor-Like Substance in Nuclei of Male Germ Cells Undergoing Meiosis. / Suzuki, Katsushi; Kamei, Takayuki; Hakamata, Yoji; Kikukawa, Keiichiro; Shiota, Kunio; Takahashi, Michio.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 198, No. 2, 1991, p. 728-731.

Research output: Contribution to journalArticle

Suzuki, Katsushi ; Kamei, Takayuki ; Hakamata, Yoji ; Kikukawa, Keiichiro ; Shiota, Kunio ; Takahashi, Michio. / Basic Fibroblast Growth Factor-Like Substance in Nuclei of Male Germ Cells Undergoing Meiosis. In: Proceedings of the Society for Experimental Biology and Medicine. 1991 ; Vol. 198, No. 2. pp. 728-731.
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