TY - JOUR
T1 - Bioinformatics tools for lncRNA research
AU - Iwakiri, Junichi
AU - Hamada, Michiaki
AU - Asai, Kiyoshi
N1 - Funding Information:
This work was supported in part by MEXT KAKENHI (Grant-in-Aid for Young Scientists (A) Grant Number 24680031 for MH; Grant-in-Aid for Scientific Research (A) Grant Number 25240044 for MH and KA; Grant-in-Aid for Scientific Research on Innovative Areas Grant Number 221S0002 ) to KA.
Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Current experimental methods to identify the functions of a large number of the candidates of long non-coding RNAs (lncRNAs) are limited in their throughput. Therefore, it is essential to know which tools are effective for understanding lncRNAs so that reasonable speed and accuracy can be achieved. In this paper, we review the currently available bioinformatics tools and databases that are useful for finding non-coding RNAs and analyzing their structures, conservation, interactions, co-expressions and localization. This article is part of a Special Issue entitled: Clues to long noncoding RNA taxonomy1, edited by Dr. Tetsuro Hirose and Dr. Shinichi Nakagawa.
AB - Current experimental methods to identify the functions of a large number of the candidates of long non-coding RNAs (lncRNAs) are limited in their throughput. Therefore, it is essential to know which tools are effective for understanding lncRNAs so that reasonable speed and accuracy can be achieved. In this paper, we review the currently available bioinformatics tools and databases that are useful for finding non-coding RNAs and analyzing their structures, conservation, interactions, co-expressions and localization. This article is part of a Special Issue entitled: Clues to long noncoding RNA taxonomy1, edited by Dr. Tetsuro Hirose and Dr. Shinichi Nakagawa.
KW - Conservation
KW - Expression
KW - LncRNA
KW - Mapping
KW - Secondary structure
UR - http://www.scopus.com/inward/record.url?scp=84953352830&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84953352830&partnerID=8YFLogxK
U2 - 10.1016/j.bbagrm.2015.07.014
DO - 10.1016/j.bbagrm.2015.07.014
M3 - Review article
C2 - 26271403
AN - SCOPUS:84953352830
SN - 1874-9399
VL - 1859
SP - 23
EP - 30
JO - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
JF - Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
IS - 1
ER -