Body mass-to-waist ratio strongly correlates with skeletal muscle volume in children

Megumi Ohta, Taishi Midorikawa, Yuki Hikihara, Shizuo Sakamoto, Yasuo Kawakami, Tetsuo Fukunaga, Hiroaki Kanehisa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose We hypothesized that body mass-to-waist ratio is strongly associated with the total-body skeletal muscle volume (SMV) in children. The purpose of the present study was to examine this hypothesis. Methods By using magnetic resonance imaging, total-body SMV (SMVMRI) was determined in 70 boys and 53 girls aged 6 to 12 years. Waist was measured at each of the level of umbilicus (Wumb) and the minimum circumference (Wmin), and the ratio of body mass to each of the two measured values was calculated (BM/Wumb and BM/Wmin, respectively). A single regression analysis was used to examine the relationships between SMVMRI and either BM/Wumb or BM/Wmin. On the basis of the obtained regression equations, SMVMRI was estimated and referred to as SMVBM/Wumb or SMVBM/Wmin. Results In both boys and girls, SMVMRI was highly correlated to BM/Wumb (r = 0.937 for boys and r = 0.939 for girls, P < 0.0001) and BM/Wmin (r = 0.915 and 0.942, P < 0.0001). R2 and the standard error of estimate for SMVBM/Wumb were 0.878 and 706.2 cm3, respectively, in boys and 0.882 and 825.3 cm3, respectively, in girls, and those for SMVBM/Wmin were 0.837 and 814.0 cm3, respectively, in boys and 0.888 and 804.1 cm3, respectively, in girls. In both boys and girls, there were no significant differences between SMVMRI and either SMVBM/Wumb or SMVBM/Wmin, without systematic errors in Band-Altman plots. There was no significant effect of model on the absolute values of the residuals in both boys and girls. Conclusion The current results indicate that body mass-to-waist ratio can be a convenient outcome measure for assessing the total-body skeletal muscle volume in children.

Original languageEnglish
Article numbere0177155
JournalPLoS One
Volume12
Issue number5
DOIs
Publication statusPublished - 2017 May 1

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waist
Muscle
skeletal muscle
Skeletal Muscle
Systematic errors
Magnetic resonance
Regression analysis
Imaging techniques
umbilicus
Umbilicus
magnetic resonance imaging
regression analysis
Regression Analysis
Magnetic Resonance Imaging
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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Body mass-to-waist ratio strongly correlates with skeletal muscle volume in children. / Ohta, Megumi; Midorikawa, Taishi; Hikihara, Yuki; Sakamoto, Shizuo; Kawakami, Yasuo; Fukunaga, Tetsuo; Kanehisa, Hiroaki.

In: PLoS One, Vol. 12, No. 5, e0177155, 01.05.2017.

Research output: Contribution to journalArticle

Ohta, Megumi ; Midorikawa, Taishi ; Hikihara, Yuki ; Sakamoto, Shizuo ; Kawakami, Yasuo ; Fukunaga, Tetsuo ; Kanehisa, Hiroaki. / Body mass-to-waist ratio strongly correlates with skeletal muscle volume in children. In: PLoS One. 2017 ; Vol. 12, No. 5.
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abstract = "Purpose We hypothesized that body mass-to-waist ratio is strongly associated with the total-body skeletal muscle volume (SMV) in children. The purpose of the present study was to examine this hypothesis. Methods By using magnetic resonance imaging, total-body SMV (SMVMRI) was determined in 70 boys and 53 girls aged 6 to 12 years. Waist was measured at each of the level of umbilicus (Wumb) and the minimum circumference (Wmin), and the ratio of body mass to each of the two measured values was calculated (BM/Wumb and BM/Wmin, respectively). A single regression analysis was used to examine the relationships between SMVMRI and either BM/Wumb or BM/Wmin. On the basis of the obtained regression equations, SMVMRI was estimated and referred to as SMVBM/Wumb or SMVBM/Wmin. Results In both boys and girls, SMVMRI was highly correlated to BM/Wumb (r = 0.937 for boys and r = 0.939 for girls, P < 0.0001) and BM/Wmin (r = 0.915 and 0.942, P < 0.0001). R2 and the standard error of estimate for SMVBM/Wumb were 0.878 and 706.2 cm3, respectively, in boys and 0.882 and 825.3 cm3, respectively, in girls, and those for SMVBM/Wmin were 0.837 and 814.0 cm3, respectively, in boys and 0.888 and 804.1 cm3, respectively, in girls. In both boys and girls, there were no significant differences between SMVMRI and either SMVBM/Wumb or SMVBM/Wmin, without systematic errors in Band-Altman plots. There was no significant effect of model on the absolute values of the residuals in both boys and girls. Conclusion The current results indicate that body mass-to-waist ratio can be a convenient outcome measure for assessing the total-body skeletal muscle volume in children.",
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AU - Ohta, Megumi

AU - Midorikawa, Taishi

AU - Hikihara, Yuki

AU - Sakamoto, Shizuo

AU - Kawakami, Yasuo

AU - Fukunaga, Tetsuo

AU - Kanehisa, Hiroaki

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AB - Purpose We hypothesized that body mass-to-waist ratio is strongly associated with the total-body skeletal muscle volume (SMV) in children. The purpose of the present study was to examine this hypothesis. Methods By using magnetic resonance imaging, total-body SMV (SMVMRI) was determined in 70 boys and 53 girls aged 6 to 12 years. Waist was measured at each of the level of umbilicus (Wumb) and the minimum circumference (Wmin), and the ratio of body mass to each of the two measured values was calculated (BM/Wumb and BM/Wmin, respectively). A single regression analysis was used to examine the relationships between SMVMRI and either BM/Wumb or BM/Wmin. On the basis of the obtained regression equations, SMVMRI was estimated and referred to as SMVBM/Wumb or SMVBM/Wmin. Results In both boys and girls, SMVMRI was highly correlated to BM/Wumb (r = 0.937 for boys and r = 0.939 for girls, P < 0.0001) and BM/Wmin (r = 0.915 and 0.942, P < 0.0001). R2 and the standard error of estimate for SMVBM/Wumb were 0.878 and 706.2 cm3, respectively, in boys and 0.882 and 825.3 cm3, respectively, in girls, and those for SMVBM/Wmin were 0.837 and 814.0 cm3, respectively, in boys and 0.888 and 804.1 cm3, respectively, in girls. In both boys and girls, there were no significant differences between SMVMRI and either SMVBM/Wumb or SMVBM/Wmin, without systematic errors in Band-Altman plots. There was no significant effect of model on the absolute values of the residuals in both boys and girls. Conclusion The current results indicate that body mass-to-waist ratio can be a convenient outcome measure for assessing the total-body skeletal muscle volume in children.

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