Abstract
Social interactions can be facilitated by action-outcome contingency, in which self-actions result in relevant responses from others. Research has indicated that the striatal reward system plays a role in generating action-outcome contingency signals. However, the neural mechanisms wherein signals regarding self-action and others' responses are integrated to generate the contingency signal remain poorly understood. We conducted a functional MRI study to test the hypothesis that brain activity representing the self modulates connectivity between the striatal reward system and sensory regions involved in the processing of others' responses. We employed a contingency task in which participants made the listener laugh by telling jokes. Participants reported more pleasure when greater laughter followed their own jokes than those of another. Self-relevant listener's responses produced stronger activation in the medial prefrontal cortex (mPFC). Laughter was associated with activity in the auditory cortex. The ventral striatum exhibited stronger activation when participants made listeners laugh than when another did. In physio-physiological interaction analyses, the ventral striatum showed interaction effects for signals extracted from the mPFC and auditory cortex. These results support the hypothesis that the mPFC, which is implicated in self-related processing, gates sensory input associated with others' responses during value processing in the ventral striatum.
| Original language | English |
|---|---|
| Journal | Neuroscience Research |
| DOIs | |
| Publication status | Accepted/In press - 2016 Dec 20 |
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Keywords
- Action-outcome contingency
- FMRI
- Reward system
- Self
- Social interaction
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Brain networks of social action-outcome contingency : The role of the ventral striatum in integrating signals from the sensory cortex and medial prefrontal cortex. / Sumiya, Motofumi; Koike, Takahiko; Okazaki, Shuntaro; Kitada, Ryo; Sadato, Norihiro.
In: Neuroscience Research, 20.12.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Brain networks of social action-outcome contingency
T2 - The role of the ventral striatum in integrating signals from the sensory cortex and medial prefrontal cortex
AU - Sumiya, Motofumi
AU - Koike, Takahiko
AU - Okazaki, Shuntaro
AU - Kitada, Ryo
AU - Sadato, Norihiro
PY - 2016/12/20
Y1 - 2016/12/20
N2 - Social interactions can be facilitated by action-outcome contingency, in which self-actions result in relevant responses from others. Research has indicated that the striatal reward system plays a role in generating action-outcome contingency signals. However, the neural mechanisms wherein signals regarding self-action and others' responses are integrated to generate the contingency signal remain poorly understood. We conducted a functional MRI study to test the hypothesis that brain activity representing the self modulates connectivity between the striatal reward system and sensory regions involved in the processing of others' responses. We employed a contingency task in which participants made the listener laugh by telling jokes. Participants reported more pleasure when greater laughter followed their own jokes than those of another. Self-relevant listener's responses produced stronger activation in the medial prefrontal cortex (mPFC). Laughter was associated with activity in the auditory cortex. The ventral striatum exhibited stronger activation when participants made listeners laugh than when another did. In physio-physiological interaction analyses, the ventral striatum showed interaction effects for signals extracted from the mPFC and auditory cortex. These results support the hypothesis that the mPFC, which is implicated in self-related processing, gates sensory input associated with others' responses during value processing in the ventral striatum.
AB - Social interactions can be facilitated by action-outcome contingency, in which self-actions result in relevant responses from others. Research has indicated that the striatal reward system plays a role in generating action-outcome contingency signals. However, the neural mechanisms wherein signals regarding self-action and others' responses are integrated to generate the contingency signal remain poorly understood. We conducted a functional MRI study to test the hypothesis that brain activity representing the self modulates connectivity between the striatal reward system and sensory regions involved in the processing of others' responses. We employed a contingency task in which participants made the listener laugh by telling jokes. Participants reported more pleasure when greater laughter followed their own jokes than those of another. Self-relevant listener's responses produced stronger activation in the medial prefrontal cortex (mPFC). Laughter was associated with activity in the auditory cortex. The ventral striatum exhibited stronger activation when participants made listeners laugh than when another did. In physio-physiological interaction analyses, the ventral striatum showed interaction effects for signals extracted from the mPFC and auditory cortex. These results support the hypothesis that the mPFC, which is implicated in self-related processing, gates sensory input associated with others' responses during value processing in the ventral striatum.
KW - Action-outcome contingency
KW - FMRI
KW - Reward system
KW - Self
KW - Social interaction
UR - http://www.scopus.com/inward/record.url?scp=85019962204&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019962204&partnerID=8YFLogxK
U2 - 10.1016/j.neures.2017.04.015
DO - 10.1016/j.neures.2017.04.015
M3 - Article
C2 - 28477977
AN - SCOPUS:85019962204
JO - Neuroscience Research
JF - Neuroscience Research
SN - 0168-0102
ER -