Building thermodynamic combinatorial libraries of quinine macrocycles

Stuart J. Rowan; Jeremy K M Sanders

Building thermodynamic combinatorial libraries of quinine macrocycles

Stuart J. Rowan, Jeremy K M Sanders^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

Thermodynamically-controlled transesterification of a predisposed cinchonidine building block with a more flexible extended quinine monomer leads to a combinatorial mixture of 11 macrocyclic receptors which is analysed by electrospray mass spectrometry; similar results with alkaloid-cholate mixtures demonstrate the generality of the approach.

Original language	English
Pages (from-to)	1407-1408
Number of pages	2
Journal	Chemical Communications
Issue number	15
Publication status	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

Cite this

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title = "Building thermodynamic combinatorial libraries of quinine macrocycles",

abstract = "Thermodynamically-controlled transesterification of a predisposed cinchonidine building block with a more flexible extended quinine monomer leads to a combinatorial mixture of 11 macrocyclic receptors which is analysed by electrospray mass spectrometry; similar results with alkaloid-cholate mixtures demonstrate the generality of the approach.",

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AU - Rowan, Stuart J.

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Building thermodynamic combinatorial libraries of quinine macrocycles

Abstract

ASJC Scopus subject areas

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