Building thermodynamic combinatorial libraries of quinine macrocycles

Stuart J. Rowan, Jeremy K M Sanders

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Thermodynamically-controlled transesterification of a predisposed cinchonidine building block with a more flexible extended quinine monomer leads to a combinatorial mixture of 11 macrocyclic receptors which is analysed by electrospray mass spectrometry; similar results with alkaloid-cholate mixtures demonstrate the generality of the approach.

Original languageEnglish
Pages (from-to)1407-1408
Number of pages2
JournalChemical Communications
Issue number15
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Quinine
Thermodynamics
Cholates
Alkaloids
Transesterification
Mass spectrometry
Monomers
cinchonidine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Rowan, S. J., & Sanders, J. K. M. (1997). Building thermodynamic combinatorial libraries of quinine macrocycles. Chemical Communications, (15), 1407-1408.

Building thermodynamic combinatorial libraries of quinine macrocycles. / Rowan, Stuart J.; Sanders, Jeremy K M.

In: Chemical Communications, No. 15, 1997, p. 1407-1408.

Research output: Contribution to journalArticle

Rowan, Stuart J. ; Sanders, Jeremy K M. / Building thermodynamic combinatorial libraries of quinine macrocycles. In: Chemical Communications. 1997 ; No. 15. pp. 1407-1408.
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