C-H alkenylation of azoles with enols and esters by nickel catalysis

Lingkui Meng, Yuko Kamada, Kei Muto, Junichiro Yamaguchi, Kenichiro Itami

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

Rather u(Ni)que: Two new C-H alkenylation reactions, that is C-H/CO alkenylation and decarbonylative C-H alkenylation, of azoles are uniquely catalyzed by Ni/dcype. These azole alkenylation reactions are successfully applied to the convergent formal synthesis of siphonazoleB.

Original languageEnglish
Pages (from-to)10048-10051
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number38
DOIs
Publication statusPublished - 2013 Sep 16
Externally publishedYes

Keywords

  • C-H activation
  • alkenes
  • heterocycles
  • natural products
  • nickel

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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