C-H alkenylation of azoles with enols and esters by nickel catalysis

Lingkui Meng, Yuko Kamada, Kei Muto, Junichiro Yamaguchi, Kenichiro Itami

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Rather u(Ni)que: Two new C-H alkenylation reactions, that is C-H/CO alkenylation and decarbonylative C-H alkenylation, of azoles are uniquely catalyzed by Ni/dcype. These azole alkenylation reactions are successfully applied to the convergent formal synthesis of siphonazoleB.

Original languageEnglish
Pages (from-to)10048-10051
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number38
DOIs
Publication statusPublished - 2013 Sep 16
Externally publishedYes

Fingerprint

Alkenylation
Azoles
Nickel
Catalysis
Esters
Carbon Monoxide

Keywords

  • alkenes
  • C-H activation
  • heterocycles
  • natural products
  • nickel

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

C-H alkenylation of azoles with enols and esters by nickel catalysis. / Meng, Lingkui; Kamada, Yuko; Muto, Kei; Yamaguchi, Junichiro; Itami, Kenichiro.

In: Angewandte Chemie - International Edition, Vol. 52, No. 38, 16.09.2013, p. 10048-10051.

Research output: Contribution to journalArticle

Meng, Lingkui ; Kamada, Yuko ; Muto, Kei ; Yamaguchi, Junichiro ; Itami, Kenichiro. / C-H alkenylation of azoles with enols and esters by nickel catalysis. In: Angewandte Chemie - International Edition. 2013 ; Vol. 52, No. 38. pp. 10048-10051.
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