C-H Borylation of Arenes: Steric-controlled Para-selectivity and Application to Molecular Nanocarbons

Yasutomo Segawa*, Mai Nagase, Yutaro Saito, Kenta Kato, Kenichiro Itami

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The selective and predictable C-H functionalization of arenes is a valuable method for the synthesis and modification of organic molecules in which regioisomer formation is often controlled by electronic factors or the presence of coordinating groups. On the other hand, the iridium-catalyzed C-H borylation of arenes can achieve unique steric-controlled regioselectivity. In this account, we describe our recent studies on the iridium-catalyzed C-H borylation of arenes: the development of novel catalytic systems that exhibit steric-controlled para-selectivity for mono-and unsymmetrically 1,2-disubstituted benzenes; and their application to the functionalization of large polycyclic aromatic hydrocarbons (molecular nanocarbons).

Original languageEnglish
Pages (from-to)994-999
Number of pages6
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume80
Issue number11
DOIs
Publication statusPublished - 2022

ASJC Scopus subject areas

  • Organic Chemistry

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