Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions

Jonathan Peake, Jeremiah J. Peiffer, Chris R. Abbiss, Kazunori Nosaka, Paul B. Laursen, Katsuhiko Suzuki

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Purpose: Heat stress might attenuate the effects of carbohydrate on immunoendocrine responses to exercise by increasing endogenous glucose production and reducing the rate of exogenous carbohydrate oxidation. The authors compared the efficacy of carbohydrate consumption on immune responses to exercise in temperate vs. hot conditions. Methods: Ten male cyclists exercised on 2 separate occasions in temperate (18.1 ± 0.4°C, 58% ± 8% relative humidity) and on another 2 occasions in hot conditions (32.2 ± 0.7 °C, 55% ± 2% relative humidity). On each occasion, the cyclists exercised in a fed state for 90 min at ∼60% VO2max and then completed a 16.1-km time trial. Every 15 min during the first 90 min of exercise, they consumed 0.24 g/kg body mass of a carbohydrate or placebo gel. Results: Neutrophil counts increased during exercise in all trials (p < .05) and were significantly lower (40%, p = .006) after the carbohydrate than after the placebo trial in 32 °C. The concentrations of serum interleukin (IL)-6, IL-8, and IL-10 and plasma granulocyte-colony-stimulating factor, myeloperoxidase, and calprotectin also increased during exercise in all trials but did not differ significantly between the carbohydrate and placebo trials. Plasma norepinephrine concentration increased during exercise in all trials and was significantly higher (50%, p = .01) after the carbohydrate vs. the placebo trial in 32°C. Conclusion: Carbohydrate ingestion attenuated neutrophil counts during exercise in hot conditions, whereas it had no effect on any other immune variables in either temperate or hot conditions.

Original languageEnglish
Pages (from-to)229-246
Number of pages18
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume18
Issue number3
Publication statusPublished - 2008 Jun

Fingerprint

Eating
Gels
Carbohydrates
ingestion
gels
exercise
carbohydrates
placebos
Placebos
Humidity
neutrophils
relative humidity
Neutrophils
Leukocyte L1 Antigen Complex
granulocyte colony-stimulating factor
myeloperoxidase
interleukin-8
Granulocyte Colony-Stimulating Factor
interleukin-10
norepinephrine

Keywords

  • Cytokines
  • Exercise
  • Leukocytes
  • Metabolism

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science

Cite this

Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions. / Peake, Jonathan; Peiffer, Jeremiah J.; Abbiss, Chris R.; Nosaka, Kazunori; Laursen, Paul B.; Suzuki, Katsuhiko.

In: International Journal of Sport Nutrition and Exercise Metabolism, Vol. 18, No. 3, 06.2008, p. 229-246.

Research output: Contribution to journalArticle

Peake, Jonathan ; Peiffer, Jeremiah J. ; Abbiss, Chris R. ; Nosaka, Kazunori ; Laursen, Paul B. ; Suzuki, Katsuhiko. / Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions. In: International Journal of Sport Nutrition and Exercise Metabolism. 2008 ; Vol. 18, No. 3. pp. 229-246.
@article{fc7cefe2fac2486a9af18d5644a6789e,
title = "Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions",
abstract = "Purpose: Heat stress might attenuate the effects of carbohydrate on immunoendocrine responses to exercise by increasing endogenous glucose production and reducing the rate of exogenous carbohydrate oxidation. The authors compared the efficacy of carbohydrate consumption on immune responses to exercise in temperate vs. hot conditions. Methods: Ten male cyclists exercised on 2 separate occasions in temperate (18.1 ± 0.4°C, 58{\%} ± 8{\%} relative humidity) and on another 2 occasions in hot conditions (32.2 ± 0.7 °C, 55{\%} ± 2{\%} relative humidity). On each occasion, the cyclists exercised in a fed state for 90 min at ∼60{\%} VO2max and then completed a 16.1-km time trial. Every 15 min during the first 90 min of exercise, they consumed 0.24 g/kg body mass of a carbohydrate or placebo gel. Results: Neutrophil counts increased during exercise in all trials (p < .05) and were significantly lower (40{\%}, p = .006) after the carbohydrate than after the placebo trial in 32 °C. The concentrations of serum interleukin (IL)-6, IL-8, and IL-10 and plasma granulocyte-colony-stimulating factor, myeloperoxidase, and calprotectin also increased during exercise in all trials but did not differ significantly between the carbohydrate and placebo trials. Plasma norepinephrine concentration increased during exercise in all trials and was significantly higher (50{\%}, p = .01) after the carbohydrate vs. the placebo trial in 32°C. Conclusion: Carbohydrate ingestion attenuated neutrophil counts during exercise in hot conditions, whereas it had no effect on any other immune variables in either temperate or hot conditions.",
keywords = "Cytokines, Exercise, Leukocytes, Metabolism",
author = "Jonathan Peake and Peiffer, {Jeremiah J.} and Abbiss, {Chris R.} and Kazunori Nosaka and Laursen, {Paul B.} and Katsuhiko Suzuki",
year = "2008",
month = "6",
language = "English",
volume = "18",
pages = "229--246",
journal = "International Journal of Sport Nutrition and Exercise Metabolism",
issn = "1526-484X",
publisher = "Human Kinetics Publishers Inc.",
number = "3",

}

TY - JOUR

T1 - Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions

AU - Peake, Jonathan

AU - Peiffer, Jeremiah J.

AU - Abbiss, Chris R.

AU - Nosaka, Kazunori

AU - Laursen, Paul B.

AU - Suzuki, Katsuhiko

PY - 2008/6

Y1 - 2008/6

N2 - Purpose: Heat stress might attenuate the effects of carbohydrate on immunoendocrine responses to exercise by increasing endogenous glucose production and reducing the rate of exogenous carbohydrate oxidation. The authors compared the efficacy of carbohydrate consumption on immune responses to exercise in temperate vs. hot conditions. Methods: Ten male cyclists exercised on 2 separate occasions in temperate (18.1 ± 0.4°C, 58% ± 8% relative humidity) and on another 2 occasions in hot conditions (32.2 ± 0.7 °C, 55% ± 2% relative humidity). On each occasion, the cyclists exercised in a fed state for 90 min at ∼60% VO2max and then completed a 16.1-km time trial. Every 15 min during the first 90 min of exercise, they consumed 0.24 g/kg body mass of a carbohydrate or placebo gel. Results: Neutrophil counts increased during exercise in all trials (p < .05) and were significantly lower (40%, p = .006) after the carbohydrate than after the placebo trial in 32 °C. The concentrations of serum interleukin (IL)-6, IL-8, and IL-10 and plasma granulocyte-colony-stimulating factor, myeloperoxidase, and calprotectin also increased during exercise in all trials but did not differ significantly between the carbohydrate and placebo trials. Plasma norepinephrine concentration increased during exercise in all trials and was significantly higher (50%, p = .01) after the carbohydrate vs. the placebo trial in 32°C. Conclusion: Carbohydrate ingestion attenuated neutrophil counts during exercise in hot conditions, whereas it had no effect on any other immune variables in either temperate or hot conditions.

AB - Purpose: Heat stress might attenuate the effects of carbohydrate on immunoendocrine responses to exercise by increasing endogenous glucose production and reducing the rate of exogenous carbohydrate oxidation. The authors compared the efficacy of carbohydrate consumption on immune responses to exercise in temperate vs. hot conditions. Methods: Ten male cyclists exercised on 2 separate occasions in temperate (18.1 ± 0.4°C, 58% ± 8% relative humidity) and on another 2 occasions in hot conditions (32.2 ± 0.7 °C, 55% ± 2% relative humidity). On each occasion, the cyclists exercised in a fed state for 90 min at ∼60% VO2max and then completed a 16.1-km time trial. Every 15 min during the first 90 min of exercise, they consumed 0.24 g/kg body mass of a carbohydrate or placebo gel. Results: Neutrophil counts increased during exercise in all trials (p < .05) and were significantly lower (40%, p = .006) after the carbohydrate than after the placebo trial in 32 °C. The concentrations of serum interleukin (IL)-6, IL-8, and IL-10 and plasma granulocyte-colony-stimulating factor, myeloperoxidase, and calprotectin also increased during exercise in all trials but did not differ significantly between the carbohydrate and placebo trials. Plasma norepinephrine concentration increased during exercise in all trials and was significantly higher (50%, p = .01) after the carbohydrate vs. the placebo trial in 32°C. Conclusion: Carbohydrate ingestion attenuated neutrophil counts during exercise in hot conditions, whereas it had no effect on any other immune variables in either temperate or hot conditions.

KW - Cytokines

KW - Exercise

KW - Leukocytes

KW - Metabolism

UR - http://www.scopus.com/inward/record.url?scp=52049123344&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52049123344&partnerID=8YFLogxK

M3 - Article

VL - 18

SP - 229

EP - 246

JO - International Journal of Sport Nutrition and Exercise Metabolism

JF - International Journal of Sport Nutrition and Exercise Metabolism

SN - 1526-484X

IS - 3

ER -