Cardiorespiratory fitness and cancer mortality in Japanese men: A prospective study

Susumu Sawada, Takashi Muto, Hiroaki Tanaka, I. Min Lee, Ralph S. Paffenbarger, Munehiro Shindo, Steven N. Blair

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Purpose: Limited data are available on the relationship between cardiorespiratory fitness and cancer mortality. We evaluated the cardiorespiratory fitness and risk of cancer mortality in Japanese men Methods: A total of 9039 men (19-59 yr) who were given a submaximal exercise test and a health examination between 1982 and 1988 and were followed for mortality up to 1999. Cardiorespiratory fitness was measured using a cycle ergometer test, and maximal oxygen uptake was estimated. Results: The mean follow-up period was slightly more than 16 yr, producing a total of 148,491 person-years of observation. There were 231 deaths, with 123 deaths due to cancer. Relative risk (RR) and 95% confidence interval (95%CI) for cancer mortality were obtained using the Cox proportional hazards model. Taking into consideration age, systolic blood pressure, body mass index, smoking habit, and alcohol habit and using the lowest physical fitness group as the reference, the RR (95% CI) for increasing quartiles of fitness were 0.75(0.48-1.16), 0.43(0.25-0.74) and 0.41(0.23-0.74); P < 0.001 for trend. Conclusion: Low cardiorespiratory fitness is associated with cancer mortality in Japanese men.

Original languageEnglish
Pages (from-to)1546-1550
Number of pages5
JournalMedicine and Science in Sports and Exercise
Volume35
Issue number9
DOIs
Publication statusPublished - 2003 Sep 1
Externally publishedYes

Fingerprint

Prospective Studies
Mortality
Neoplasms
Habits
Blood Pressure
Physical Fitness
Exercise Test
Proportional Hazards Models
Body Mass Index
Smoking
Alcohols
Observation
Cardiorespiratory Fitness
Confidence Intervals
Oxygen
Health

Keywords

  • Alcohol drinking
  • Cohort study
  • Epidemiology
  • Maximal oxygen uptake
  • Smoking

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Cardiorespiratory fitness and cancer mortality in Japanese men : A prospective study. / Sawada, Susumu; Muto, Takashi; Tanaka, Hiroaki; Lee, I. Min; Paffenbarger, Ralph S.; Shindo, Munehiro; Blair, Steven N.

In: Medicine and Science in Sports and Exercise, Vol. 35, No. 9, 01.09.2003, p. 1546-1550.

Research output: Contribution to journalArticle

Sawada, Susumu ; Muto, Takashi ; Tanaka, Hiroaki ; Lee, I. Min ; Paffenbarger, Ralph S. ; Shindo, Munehiro ; Blair, Steven N. / Cardiorespiratory fitness and cancer mortality in Japanese men : A prospective study. In: Medicine and Science in Sports and Exercise. 2003 ; Vol. 35, No. 9. pp. 1546-1550.
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