Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides

Shuhei Obinata, Yu ki Tahara, Kyalo Stephen Kanyiva, Takanori Shibata

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.

Original languageEnglish
Pages (from-to)1121-1131
Number of pages11
JournalHeterocycles
Volume95
Issue number2
DOIs
Publication statusPublished - 2017

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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