Cationic iridium-catalyzed C-H alkylation of 2-substituted pyridine N-oxides with acrylates

Takanori Shibata; Hideaki Takano

doi:10.1039/c4qo00355a

Cationic iridium-catalyzed C-H alkylation of 2-substituted pyridine N-oxides with acrylates

Takanori Shibata^*, Hideaki Takano

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C-H alkylation at the C6-position.

Original language	English
Pages (from-to)	383-387
Number of pages	5
Journal	Organic Chemistry Frontiers
Volume	2
Issue number	4
DOIs	https://doi.org/10.1039/c4qo00355a
Publication status	Published - 2015 Apr 1

ASJC Scopus subject areas

Organic Chemistry

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title = "Cationic iridium-catalyzed C-H alkylation of 2-substituted pyridine N-oxides with acrylates",

abstract = "The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C-H alkylation at the C6-position.",

author = "Takanori Shibata and Hideaki Takano",

year = "2015",

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doi = "10.1039/c4qo00355a",

language = "English",

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AU - Takano, Hideaki

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Y1 - 2015/4/1

N2 - The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C-H alkylation at the C6-position.

AB - The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C-H alkylation at the C6-position.

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U2 - 10.1039/c4qo00355a

DO - 10.1039/c4qo00355a

M3 - Article

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ER -

Cationic iridium-catalyzed C-H alkylation of 2-substituted pyridine N-oxides with acrylates

Abstract

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