Cationic iridium-catalyzed C-H alkylation of 2-substituted pyridine N-oxides with acrylates

Takanori Shibata, Hideaki Takano

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    21 Citations (Scopus)


    The reaction of 2-arylmethyl-, 2-aryl-, and 2-alkyl substituted pyridine N-oxides with acrylates proceeded in the presence of a cationic Ir-rac-BINAP catalyst under heating conditions. Various 2,6-disubstituted pyridine N-oxides were obtained by C-H alkylation at the C6-position.

    Original languageEnglish
    Pages (from-to)383-387
    Number of pages5
    JournalOrganic Chemistry Frontiers
    Issue number4
    Publication statusPublished - 2015 Apr 1


    ASJC Scopus subject areas

    • Organic Chemistry

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