Cell cultures on a super water-repellent alkylketene dimer surface

Hu Yan; Hatsuki Shiga; Etsuro Ito; Kaoru Tsujii

doi:10.1142/S0219581X06005297

Cell cultures on a super water-repellent alkylketene dimer surface

Hu Yan, Hatsuki Shiga, Etsuro Ito, Kaoru Tsujii

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The fractal alkylketene dimer (AKD) surface is an artificial super water-repellent one with a high contact angle of 174°, therefore, may provide special surface circumstances for studies of biological cells such as cell cultures. The experimental results indicated that the distribution of F-actin in the astrocytes cultured on the fractal AKD-coated dishes showed the stellate shape, while that in the astrocytes cultured on the poly-L-lysine-coated coverslips showed the formation of long alignment. The morphological change of astrocytes is induced by the fractal AKD surface, and the result suggests that astrocyte differentiation is stimulated by the fractal AKD surface.

Original language	English
Article number	00529
Pages (from-to)	871-876
Number of pages	6
Journal	International Journal of Nanoscience
Volume	5
Issue number	6
DOIs	https://doi.org/10.1142/S0219581X06005297
Publication status	Published - 2006 Dec 1
Externally published	Yes

Keywords

Astrocytes
Cell culture
Fractal structure
Glial cell
Super water-repellency

ASJC Scopus subject areas

Biotechnology
Bioengineering
Materials Science(all)
Condensed Matter Physics
Computer Science Applications
Electrical and Electronic Engineering

Access to Document

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AU - Yan, Hu

AU - Shiga, Hatsuki

AU - Ito, Etsuro

AU - Tsujii, Kaoru

PY - 2006/12/1

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AB - The fractal alkylketene dimer (AKD) surface is an artificial super water-repellent one with a high contact angle of 174°, therefore, may provide special surface circumstances for studies of biological cells such as cell cultures. The experimental results indicated that the distribution of F-actin in the astrocytes cultured on the fractal AKD-coated dishes showed the stellate shape, while that in the astrocytes cultured on the poly-L-lysine-coated coverslips showed the formation of long alignment. The morphological change of astrocytes is induced by the fractal AKD surface, and the result suggests that astrocyte differentiation is stimulated by the fractal AKD surface.

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KW - Cell culture

KW - Fractal structure

KW - Glial cell

KW - Super water-repellency

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